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2011 Bio-IT World Best of Show


June 8, 2011 | Bio-IT World's panel of judges chose 13 finalists in four categories for the 2011 Bio-IT World Best of Show awards. After meeting with the finalists and seeing product demonstrations at the Bio-IT World Expo, the judges named four winning products. What follows are the finalists and winner in each category.

Clinical Trials

WINNER: NextDocs extends SharePoint’s robust feature set to address the rigorous regulatory requirements that govern global biopharmaceutical organizations. All companies in the pharmaceutical industry must maintain a trial master file (TMF) for each clinical trial they sponsor. Even though regulatory guidance (such as ICH E6) exists, there is no comprehensive common model for managing those documents. NextDocs’ is fully configured for use in managing clinical trial documents, and which could be validated and deployed by doing nothing more than adding specific information about your products, studies, etc. to pre-existing lists, importing your templates, and adding your users to appropriate roles. NextDocs Clinical includes a complete inventory built on DIA EDM Reference Model specifications, role-based security, and audit trails to enable a complete electronic trial master file (eTMF).
More information: www.nextdocs.com

ClearTrial’s ClearTrial 4 clinical trial operations software makes the planning, forecasting, and tracking of clinical projects and financial performance faster and more accurate. The software allows biopharmaceutical and medical device companies to compress study planning cycle-times, reduce execution timelines, and reduce costs while maintaining study feasibility.
More information: www.cleartrial.com

PharmaPros’ Dataflow Manager is an automated study management solution designed to enable in-stream access to study data across the multiple systems and vendors being used to manage today’s complex clinical trials. Dataflow Manager automatically updates the status of a trial against every data source in the study, (Labs, CRFs, EDC, IVRS, CTMS, ePRO, Images) providing an integrated view of the study data.
More information:
www.pharmapros.com/ 

IT Hardware & Infrastructure

WINNER: The Microway BioStack-LS is a modular, extensible cluster for life science researchers. With 84 cores and 14 GPUs it provides dense compute power that’s easy to use. With over 15 teraflops of InfiniBand-connected computing power spread over 6272 GPU and 84 x 86 CPU cores, the BioStack-LS provides vastly superior performance to traditional compute clusters. To ensure ease of use it is equipped with Bright Computing advanced cluster management tools for node monitoring, rapid deployment of new nodes, and full GPU integration and management.
More information: www.microway.com/tesla/clusters.html

Symmetric Computing Trio’s Departmental SuperComputer got its name by being priced within many department budgets. The Trio is a 768-GB shared memory, 96-core supercomputer with a 1 teraflop rating (SPECfp-2006 of 1602) for only $84,100. During benchmark tests, the Trio ran BLAST, HMMER3 and NAMD at performance levels comparable to multiple million dollar supercomputers.
More information:
www.SymmetricComputing.com 

SGI Altix UV is a scalable, symmetric multiprocessing (SMP) computer system that addresses the highest compute and data requirements in the industry. Built using Intel Xeon processor 7500 series CPUs, Altix UV scales to unprecedented heights, with a single instance of standard Linux or Windows, and is able to address up to 2048 cores (4096 threads).
More information: www.sgi.com

Panasas’ PAS 12 claims to be the highest performing, highest capacity parallel storage system available. It brings appliance-like plug-and-play simplicity to storage deployments and provides industry-leading performance and unrivaled performance per gigabyte for complex research-critical applications. Each 4U chassis houses up to 40 terabytes (TB) of storage at 1.5 gigabytes per second (GB/s) performance throughput.
More information:
www.panasas.com/products/pas-12.php 

Informatics Tools and Data

WINNER: OpenEye’s FastROCS (Rapid Overlay of Chemical Structures) application represents a speed improvement in 3-D shape searching by two orders of magnitude to improve the timing of modeling tasks and change the role modeling can have in drug discovery. FastROCS dramatically improves the “time-to-answer” of 3-D shape similarity searches. One collaborator has reported a 175-fold improvement in the “time-to-answer” of a typical query (28 seconds compared to 82 minutes). FastROCS does this by leveraging the emerging capabilities of the GPU (Graphics Processor Unit) to accelerate computational tasks. A single GPU running FastROCS is equivalent to 250 CPU cores running ROCS.
More information: www.eyesopen.com

DNASTAR recently released SeqMan NGen 3 and its companion SeqMan Pro software, a novel product suite supports assembly of any size genome on a desktop computer. Available on Windows, Macintosh and Linux operating systems, SeqMan NGen 3 can assemble a whole human genome at normal depths of coverage on a desktop computer in less than a day. Bacterial genomes can be assembled in less than a minute. For the first time, life scientists have available at their fingertips all the capacity and algorithmic complexity required to assemble any size genome against a template.
More information:
www.dnastar.com/t-products-seqman-ngen.aspx

Omixon’s Gapped SOLiD Alignment plug-in for CLC bio workbench/server enables the most accurate genomic variant analysis fully integrated with the capabilities of CLC bio Workbench and Server. The plug-in is fully integrated into CLC bio Workbench to enable users to work in a familiar environment and boasts the lowest amount of unmapped or incorrectly mapped reads. The plug-in finds more variants than the competitors from the same run.
More information: www.omixon.com

Web-Based Tools and Services

WINNER: Denodo Platform 4.7’s advanced query optimization and data orchestration engine enables performance similar to what one would get from a dedicated data warehouse without the associated costs. High performance is achieved by orchestrating real-time query federation, intelligent caching and pre-processing information into small temporary data stores. This minimizes costly physical replication. Denodo provides an extensive connector library to create normalized schemas across internal/external, structured, semi-structured and unstructured data sources. The Denodo platform rules engine then matches, transforms, cleanses and combines the data from these multiple sources into a normalized business view that a user or application can use.
More information: www.denodo.com

Japan Bioinformatics’ Simbiot is a comprehensive bioinformatic infrastructure that supports data management, analysis and collaboration in a secure and scalable environment. Simbiot manages raw data and analysis results and creates in silico experiments combining new data, legacy data and public data. Simbiot offers Cloud-based deployment which can dynamically obtain needed disk and computational resources. Users can upload data directly to Simbiot, obtain them from public domain or via an easy LIMS integration.
More information: www.simbiotnetwork.com

IO Informatics’ Sentient Knowledge Explorer uses semantic technologies to integrate data from virtually any source into coherent, unified knowledge bases. This feature-rich product permits rapid, iterative import, management, editing and application of thesauri, ontologies, RDF creation methods, provenance, integration testing and visualization as well as integrated data browsing, search and sharing—all using a simple, visual, point-and-click interface.
More information:
www.io-informatics.com 

 

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