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The new Howard Hughes Medical Institute computing cluster at Janelia Farm puts a premium on expandability and speed. By Randy Barrett July 26, 2010 | Computational biologists have a need for speed. The computing cluster at the Howard Hughes Medical
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Community Service Prize Winner Royal Society of Chemistry nominated by Collaborative Drug Discovery Project ChemSpider By Allison Proffitt July 26, 2010 | ChemSpider started as a “hobby project out of a basement” in 2007, says Antony Williams, ChemSpider’s VP of
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IT & Informatics Winner The Scripps Research Institute nominated by SciQuest Project Procurement Transformation By Allison Proffitt July 26, 2010 | The Scripps Research Institute (TSRI) boasts 534 faculty, 735 post doctoral researchers, 218 graduate students and 1,445 lab and
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Commentary | Pharmaceutical and health care professionals are often faced with mishandled information, fines, and the resulting patient outrage. Fortunately, there are three ways professionals can avoid facing the same situation: Setting the security bar higher, securing data prior to shipment, and obtaining frequent third-party verification.
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Bio-IT World | iPierian, a San Francisco-based biopharmaceutical company using patient-derived induced pluripotent stem cells (iPSCs) for drug discovery, has closed $22 million Series B financing led by Google Ventures.
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Bio-IT World Weekly Update: May 25
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Wellcome Trust | Professor Mike Stratton has been appointed the new Director of the Wellcome Trust Sanger Institute. Stratton has been Deputy Director of the Institute since 2007.
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By Allison Proffitt May 18, 2010 | Ningbo is located 138 miles south of Shanghai—a pleasant drive. We crossed the Hangzhou Bay Bridge, the longest trans oceanic bridge in the world, to get there, but the fog in January was
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By Nancy J. Kelley May 18, 2010 | Ten years ago, the mapping of the human genome ushered in a new era of research and medicine. Since then, much has been accomplished in unraveling the causes and complex human disease.
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Bio-IT World | Accelrys and Symyx Technologies have announced that the two informatics companies will merge in an all-stock deal expected to close by June 2010. The name of the new company has not yet been announced.
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Bio-IT World | The Bioinformatics Organization has named Alex Bateman, a senior investigator at the Wellcome Trust Sanger Institute in Cambridge, UK, as the winner of the 2010 Benjamin Franklin Award.
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Bio-IT World | As Emanuel Petricoin III tells it, “the planets aligned”: a long-standing partnership yields access to a unique sample set, an in-house technology goes from bench to bedside, and suddenly one of the best-selling leukemia drugs looks like a good fit for metastatic colorectal cancer. Petricoin and his colleagues have a model of what personalized medicine could look like.
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High Quality Sample PrepCaliper Life Sciences has introduced the LabChip XT, an automated nucleic acid fractionation instrument. This is Caliper’s first instrument designed specifically to aid next gen sequencing. The LabChip XT, developed in collaboration with leading genome centers, addresses an
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March 16, 2010 | As Emanuel Petricoin III tells it, “the planets aligned”: a long-standing partnership yields access to a unique sample set, an in-house technology goes from bench to bedside, and suddenly one of the best-selling leukemia drugs looks like a good fit for metastatic colorectal cancer. Petricoin and his colleagues have a model of what personalized medicine could look like.
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March 16, 2010 | There isn’t an issue of Bio•IT World that doesn’t address the subject of personalized medicine in some respect. Many of our stories tackle issues of making medicine more predictive, more preventive, and more participatory—the concept encapsulated in “P4 medicine” by Lee Hood and colleagues (see “ISB Is a Sure Cure for Summer Doldrums,” Bio•IT World, July 2007). In recent years, the first examples of personalized diagnostics and therapies have emerged, with Herceptin leading the way. Biomarkers, gene expression profiles and next-generation sequencing approaches are dramatically changing the stratification and management of cancer. And the arrival of consumer genomics two years ago has empowered patients as never before.
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March 16, 2010 | In a surprising twist in the next-generation sequencing horse race, Susan Hardin, co-founder of VisiGen Biotechnologies, has filed suit against Life Technologies, which acquired her company in 2008, for fraud and breach of contract. The suit seeks total damages in excess of $300 million.
Hardin, a former associate professor at the University of Houston, founded VisiGen in 2000 as one of the first biotech companies aiming to replace Sanger sequencing and crack the $1000 genome in less than a day using single-molecule DNA sequencing methods (see below). In August 2008, Invitrogen acquired VisiGen for $21 million. Invitrogen subsequently merged with Applied Biosystems to form Life Technologies. Hardin stayed on as a director of R&D for Life Technologies, a position she resigned last year.
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March 16, 2010 | In the fall of 2005, Michael Gilman left his position as executive VP research at Biogen Idec after more than six years. “I had no particular idea of what I wanted to do, I just wanted to do something different,” he said.
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Bio-IT World | Certain signs of trait selection among human populations are easy to recognize—skin pigmentation, height, shape, and the ability to digest lactose are some examples. In a superb paper published in Science, Pardis Sabeti and colleagues at Harvard University and the Broad Institute describe a powerful computational strategy for systematically searching across the human genome to pinpoint signatures of positive selection.
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Bio-IT World | Working in 2010, it is easy to forget the bumpy road first travelled by microarray technology to win respect. In 2001 - when Expression Analysis (EA) was formed - the hopes for microarray technology were high but so was skepticism. Steve McPhail, EA’s CEO, remembers the rugged road well.
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Bio-IT World | The Bioinformatics Organization (bioinformatics.org) has announced the names of the five nominees for the 2010 Benjamin Franklin Award. The winner will be presented with the award and deliver a lecture at the Bio-IT World Conference & Expo, on Wednesday, April 21.
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The Role of Analytics in Transforming Healthcare Sharing many of the data challenges and opportunities faced by Healthcare, the Life Sciences industry remains focused on delivering new, innovative therapies and solutions to patients in a cost effective, timely and safe way. With spiraling R&D costs, new methods such as adaptive trials, and never ending need for deep pharmacovigilance, the Life Sciences companies that effectively use analytics to explore, monitor and optimize their business will rapidly become the new leaders. Oracle’s strategy—built upon Enterprise Health Analytics and Health Data Warehouse Foundation—provides a powerful, practical, and extensible approach to delivering the IT analytics infrastructure required to confront the worldwide healthcare challenge.
BPM-Based Case Management Approach to Optimizing Clinical Trial Efficiency Business Process Management (BPM) software offers liberation in the planning and management of clinical trials today. SmartBPM provides the components for automating critical clinical trial processes ranging from protocol development and patient enrollment to site management and investigator payments. Advantages are: - Potentially stunning return on investment at multiple levels.
- A 500%, or better, increase in application development time by directly executing business requirements
- Improved customer retention
- A 50% possible reduction in training time
Discovered is opportunity to enhance relationships with investigators, subjects, and regulators while bringing momentum to a technology-impaired study startup phase. Learn more about SmartBPM in this complimentary white paper.
Next-gen Cloud-based eClinical New technologies are available to leverage Cloud Computing in managing clinical trial data. This paper discusses a next generation eClinical
platform that: - Speeds trial set up
- Accommodates changes with zero downtime
- Integrates effectively with other clinical trial technology systems
It is offered with either software-as-a-service (SaaS), or turnkey infrastructure options in which the user organization operates their own cloud using their IT teams, within their data centers. Read this paper to learn and decide how best to leverage cloud computing’s many strengths for your organization’s particular needs.
Software Engineer – Computational Biology Center
Memorial Sloan-Kettering Cancer Center seeks an Engineer to design and develop complex data analysis systems in support of cancer genomics research projects at the Computational Biology Center. Qualified candidate will have a BA, 5+ years of software development experience and expert knowledge of Java, SQL, and HTML.
Apply: www.mskcciscareers.org. Equal opportunity and affirmative action employer.
Bio-IT World proudly presents the Bio-IT World Web Symposia Series covering a broad array of topics within the life sciences and drug development enterprise.
Leveraging BPM to Increase Efficiencies in Clinical Trial Case Management
August 3, 2010 | 1:00 – 2:30 p.m. EST
Sponsored by: Pegasystems
Program Details | Register Here
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