Up Front

• Oracle OpenWorld 2006: Pharma Stuck on Semantic Web
  Pfizer, Lilly embrace RDF to improve drug development.
• Merck's $1.1 Billion Bet on RNAi 
  Merck acquires Sirna in a billion-dollar gamble on gene-silencing technology.
• Managing Data on the Go
  FULLY EQUIPPED - GeneGo's suite of software and database products facilitates data analysis.
  By Robert M. Frederickson
• Signs of Life in Life Sciences IT Spending
  INSIGHTS & OUTLOOK - IT total global growth rates continue to rise.
  By Alan S. Louie
• Personal, Virtual Machines
  INSIDE THE BOX - Virtualization becomes a reality for individual users.
  By Chris Dwan
• News Briefs

Computational Biology

• The Quest to Make Sequence Sense
  New software from Gene-IT, Cartesian Gridspeed, and Gene Codes.

Computational Development

• Jubilant Curries Favor with BioPharma
  Indian drug discovery companies attracting Big Pharma attention. 

IT/Workflow

• Building a Bridge Over Pharma with IT
  CHI conference highlights technology, collaboration.

Clinical Research

• Putting EDC on the Fast Track
  New software helps clinical trial planners do the right thing.

In Every Issue

• Compute for the Cure
  FIRST BASE - Called "the Google of drug discovery," the Connectivity Map from the Broad Institute offers a computational approach to drug identification.
  By Kevin Davies 
• On the CASP of a DREAM
  THE RUSSELL TRANSCRIPT - A new competition promises some interesting outcomes.
  By John Russell
• New Products