COVER STORY

Green Pastures for Discovery Informatics 
Tripos believes its sophisticated small-molecule synthesis and modeling software could fix pharma's chemical dependency.
By Kevin Davies

View from the Future
Enjoy this retrospective from the future that's part whimsy, part forecast, and partly plausible.
By Simon Easteal and Pythia Demosthenes

STRATEGIC INSIGHTS: Intellectual Property

IP Protection and E-Lab Notebooks 
Review of evidence that courts will accept electronic management of IP
By Patrick Tormey

Improving the IP Search
New tools handle the complexity and growing number of biotech patents.
By David Warshawsky

Business + Strategy

• Millennium Imaging
  DRUG DEVELOPMENT - Spectacular suite of imaging tools speeds research.
• VC Funding on the Rise 
  INVESTMENT - Purse strings loosen but not for all biotechs.
• Ratcheting up PGX
  CONVERSATION - PWC's Lefteroff talks about needed next steps.
• Got Good Informatics? 
  STANDARDS - Howard Asher leads effort to create GIP measures.
• Laboratory Networking
  NOTHING VENTURED - Building the networked laboratory is a huge opportunity.
  By Michael Greeley
• CRM Analytics Defined
  INSIGHTS | OUTLOOK - It's all about the content.
  By Charles Firneno
• News Blast

Science + Technology 

• Animal Pharm
  DRUG DISCOVERY - Harvard researcher Randall Peterson leads the in vivo modeling charge.
• Biomarker Challenge 
  PROTEOMICS - Focus on reliability and reproducibility sharpens.
• Skirting Light's Limit
  FULLY EQUIPPED - Nanoshells and Raman scattering break new ground.
  By Robert M. Frederickson
• News Blast
• New Products

IT + Informatics 

• First Blue Gene Paper
  HPC - IBM's supercomputer delivers new view of rhodopsin interactions.
• Rethinking Pen and Paper
  GUEST COMMENTARY - Dump paper? HP has better idea - the digital pen.
• Trial Registries Debate
  CLINICAL TRIALS - Pushing the rock uphill is difficult indeed.
• Medidata on the Move
  EDC TOOLS - Clinical technology supplier lands EDC trial for 70,000 patients.
• Tiger Unleashed
  INSIDE THE BOX - Apple's latest OS behaves well right out of the box, says our expert.
  By Bill Van Etten
• News Blast
• New Products

In Every Issue

• Single Molecule Signals
  FIRST BASE - The $1000 genome hype has been replaced by something more realistic.
  By Kevin Davies
• It's a Bug's Life
  THE RUSSELL TRANSCRIPT - Modeling microbial metabolism looks promising.
  By John Russell