Cover Story
The Platform Diet 
Nicolas Saccomano, Pfizer's head of technology for R+D talks about dropping attrition rates, finding new talent, curbing the company's appetite for new tools - and empowering scientists with higher-quality data.

Tackling cGMP; A Better Way to Innovate
PHARMA-IT - Special Section examines manufacturing compliance and new product development issues.

Practical Clinical Technologies
The push to adopt e-SOP's gathers momentum in wake of drug seizures.

• Social Medicine, Canadian Style
  COMPANY TO WATCH - Aspreva Pharmaceuticals finds new hope in old drugs - to big pharma's delight.
• Perlegen SNP Bonanza 
  GENOMICS - 1.6 million SNP's donated to public databases for new map.
• New HHMI Investigators 
  BIOMEDICAL RESEARCH - Hughes expects star scientists to soar..
• RNAi Consortium 
  DRUG DISCOVERY - Organizations start work on RNAi toolkit.
• Systems Biology
  NOTHING VENTURED - Tips for companies seeking success in systems biology.
  By Michael Greeley
• Systems Pathology 
  INSIGHTS | OUTLOOK - New approach has potential to revolutionize pathology assessment.
  By Irena Melnikova
• News Blast

Science + Technology

• Finally, PGX Guidance
  BIOMARKERS - FDA clarifies its plan for using pharmacogenomics data.
• Pinpointing Blindness 
  GENOTYPING - Sequonom technology discovers AMD gene.
• Full Virus Sequence
  Cluster analysis is key to Solexa's sequence of Phi-X174.
• Pittcon Smorgasbord
  LAB EQUIPMENT - There was plenty to feast on at this year's equipment extravaganza. Nanoshells and Raman scattering break new ground.
• Protein Analysis Advances
  FULLY EQUIPPED - Pathblast provides clues to interaction networks. Nanoshells and Raman scattering break new ground.
• News Blast
• New Products

IT + Informatics

• Tsunami Taps Gene Codes
  INFORMATICS - Michigan company is picked to help identify victims.
• Microsoft's Digital Pharma Initiative
  SOFTWARE TOOLS - Support by ISV community is critical to success.
• DecisionSite Upgraded 
  INFORMATICS - Interactive curve fitting to screen out bad data.
• New Tools, New Biology
  INSIDE THE BOX - New interfaces are required for next generation of students.
• News Blast
• New Products

In Every Issue

• Cellf Examination 
  FIRST BASE - Bio-IT World Editor-in-Chief discusses results of his personal genotyping.
  By Kevin Davies
• Stargazing with Finneran 
  THE RUSSELL TRANSCRIPT - Mass Bio's new chief must establish his own agenda.
  By John Russell