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We invite your comments and feedback for this edition of Weekly Update. 

Allison Proffitt 
Managing Editor 
 
 
 
 
 
 
 
LATEST eNEWSLETTERS 
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December 19, 2011 
 
 
 
 
 
 
 

Featured Articles

 
A QuantuMDx Leap for Handheld DNA Sequencing 
Bio-IT World (Jan 17 2012) Next-Gen Data , Technologies 
Speaking for the first time in his life as a commercial consultant rather than a public servant, Sir John Burn, a highly respected clinical geneticist in the United Kingdom, provided the first glimpse at a nanowire technology for rapid DNA genotyping that could eventually mature into the world’s first handheld DNA sequencer. 
Picture This: Molecular Maya Puts Life in Life Science Animations 
Bio-IT World (Jan 12 2012) Bio-IT , Discovery Informatics 
Bio-IT World | In 2010, a reporter sat in a Life Technologies hotel suite admiring a promotional video illustrating one of the company’s latest research projects—a single-molecule sequencing system featuring enzymes tethered to fluorescing quantum dots. The video was impressive not merely for pushing the boundaries of sequencing technology, but equally for showcasing some powerful production qualities in 3D animation and rendering that, until recently, would have seemed the provenance of a Pixar movie. 
 
  
 
Scientists Offer The Edge Their Most Beautiful Explanations 
Bio-IT World (Jan 16 2012) Bio-IT , Medical Informatics , Technologies 
A stunning assembly of almost 200 scientists and artists -- including the likes of Richard Dawkins, George Church, Nathan Myhrvold, Brian Eno and Alan Alda -- answer The Edge.org's Question of the Year: 'What is your favorite deep, elegant, or beautiful explanation?' 
New biotech to develop ‘super drugs’ 
Home - BostonHerald.com (Jan 16 2012) Discovery Informatics , Drug & Disease Targets 
Three leading researchers in the fields of chemistry and nano-medicine have teamed up to start a Watertown company that aims to develop a new class of “super drugs” to fight diseases such as cancer. Dr. Omid Farokhzad of Harvard Medical School and doctors Robert Langer and Stephen Lippard of MIT founded Blend Therapeutics in August to meet what they saw as an urgent need. 
Health Care's X-Prize 
Bio-IT World (Jan 13 2012) 
The Guardian | The X-Prize has launched a new competition with a $10m prize to be the first to [re?] invent Dr. Spock's tricorder. The Tricorder Qualcomm X-Prize, co-funded by Qualcomm and the X-Prize Foundation, is named for the instant-diagnosis gadget from Star Trek. The competition's goal is a consumer-friendly product that will diagnose 15 common conditions. 
Mary Jane's First iPad App 
Bio-IT World (Jan 13 2012) Bio-IT , Business & Market Insights , Discovery Informatics 
Bio-IT World | Kevin McKernan's new venture, Medicinal Genomics, is focusing on the cannabis genome, and the company has just released a new iPad app called "Jane-Ome" that allows users to explore the scientific basis for medical marijuana use. 
 
 
 
IBM creates data storage at the atomic level 
Technology News (Jan 12 2012) Discovery Informatics , IT Infrastructure 
A new discovery by Big Blue researchers suggests that it's possible to store a bit of information in as little as 12 magnetic atoms. Today's disk drives require a million atoms to store a bit. 
DNA Sequencing is Now Improving Faster Than Moore's Law! 
Forbes.com (Jan 12 2012) Bio-IT 
A ?worldwide genomics revolution? is upon us. The genomics industry marked a new milestone yesterday. As Forbes' reported in three separate posts and nearly 100 related Tweets, the two leading manufacturers of DNA sequencing instruments announced almost simultaneously at an investors' conference that they would introduce new machines this year capable of sequencing an entire ... 
Do We Need Doctors Or Algorithms? 
Bio-IT World (Jan 12 2012) Business & Market Insights 
Tech Crunch | Vinod Khosla, the legendary Silicon Valley investor and founder of Khosla Ventures, discusses the wide-ranging impact of technology -- from mobile technology to increasingly sophisticated algorithms -- on medicine and healthcare, helping to empower patients. 
Researchers Find Familial Prostate Cancer Gene Mutation 
Bio-IT World (Jan 12 2012) Discovery Informatics , Medical Informatics 
MedPage Today | Scientists writing in the New England Journal of Medicine have identified the first hereditary mutation for prostate cancer risk in a gene called HOXB13, a discovery that could provide new mechanistic insights into this common cancer. 
Biotech Firms Battle Over Same Day Genomes 
Forbes.com (Jan 11 2012) Business & Market Insights , Next-Gen Data 
Illumina's new DNA sequencing announcement came only hours after Illumina’s main competitor, Life Technologies, announced that it would be launching a machine that would eventually be able to sequence a human genome in in just hours for a per-genome cost of as little as $1,000. 
Sanofi Inks Two New Genomics Partnerships in Boston 
Bio-IT World (Jan 11 2012) Bio-IT , Clinical Trial Informatics , Discovery Informatics 
Mass High Tech | It's been a busy month for French pharma company Sanofi, as they ink deals with two Boston-based genomics firms, cancer diagnostic company Foundation Medicine and natural products start-up Warp Drive Bio, in which Sanofi will invest up to $125 million. 
The Unstable Equilibrium of the Bioinformatics Org Chart 
Bio-IT World (Jan 11 2012) Clinical Trial Informatics , Discovery Informatics 
Bio-IT World | In most organizations, the human resources of bioinformatics are a regular source of tension. Unless you’re particularly lucky, you can be plagued by politics, illogical decision making, disappointment, and low productivity. While you can have these problems in a properly-balanced organization, there are certain org charts in which they are endemic. 
Rackspace: Bull and Bear Cases Revisited 
Forbes.com (Jan 10 2012) IT Infrastructure 
Following my Rackspace:?? Bull and Bear Cases article, I had the opportunity to speak with Bryan McGrath, Director of Finance, at Rackspace to discuss the bear case, capital efficiencies, customer base and competition.?? Herein are the takeaways from that discussion. If there is one thing Rackspace management wants to avoid, it's "stranded capital."?? adheres to ... 
The Situation at the FDA: We Are All to Blame 
xconomy.com (Jan 10 2012) Government and Regulations , Therapeutics Indications 
[Editor's Note: We asked selected Xconomists a series of questions designed to zero in on the big issues of the year, including "What would you be willing to throw a punch over?"] It takes a lot to get me riled-up—I’m overly rational, if anything. Outside of the bad behavior we were supposed to outgrow in [...] 
Ion Torrent Introduces New Sequencer, Touts Imminent Arrival of the $1,000 Genome 
Bio-IT World (Jan 10 2012) Bio-IT , Clinical Trial Informatics , Next-Gen Data 
Reuters | Life Technologies, the parent company of Ion Torrent Systems, says it is taking orders for the new benchtop Ion Proton Sequencer, which it predicts will have the capacity in the next 12 months to deliver a $1,000 human genome in a day. 
 
GenomeQuest awards genetic sequencing software grants 
Mass High Tech Business News (Jan 10 2012) Bio-IT , Discovery Informatics , Medical Informatics , Next-Gen Data , Therapeutics Indications 
GenomeQuest is supporting the use of next generation sequencing-based tests by giving about $120,000 in software and service grants to six U.S. laboratories. 
 
 
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