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We invite your comments and feedback for this edition of Weekly Update. 

Allison Proffitt 
Managing Editor 
 
 
 
LATEST eNEWSLETTERS 
eCliniqua 
January 23, 2012 
 
 
 
 
 
 
 

Featured Articles

 
Two Guys and a Credit Card: Metrum’s Amazon Cloud Makeover 
Bio-IT World (Feb 14 2012) IT Infrastructure , Technologies 

A case study in transferring a life sciences IT infrastructure fully into the cloud

Flatley Flatly Rejects Roche Unsolicited Bid for Illumina 
Bio-IT World (Feb 8 2012) Discovery Informatics 
BusinessWire | Illumina CEO Jay Flatley has informed Roche that its unsolicited tender offer of $44.50 per share is "grossly inadequate in multiple respects, dramatically undervalues Illumina and is contrary to the best interests of Illumina's stockholders."
 
  
 
The Drug Shortage Crisis in America 
Forbes.com (Feb 13 2012) Discovery Informatics , Medical Informatics 
Two Congressmen introduced bipartisan legislation to address prescription drug shortages last week.?? The Drug Shortage Prevention Act would create a 'Critical Drug List' that would identify drugs that are susceptible to shortage, and require the FDA to develop a system to notify the public if a medicine is added to the list. The bill would ...
The New Anti-Science Assault on US Schools 
Bio-IT World (Feb 13 2012) 
The Guardian | Not withstanding the famous 2005 Pennsylvania court ruling on intelligent design, anti-evolution campaigners in the United States are now combining with climate change deniers to continue to undermine public education.
BGI Researchers Report More Evidence of RNA Editing 
Bio-IT World (Feb 13 2012) Discovery Informatics , Drug & Disease Targets 
Bio-IT World | In a study published online in Nature Biotechnology, BGI researchers have reported evidence of extensive RNA editing in human cells. The paper is a follow up study to last May's Science paper that initially reported sequence differences between mRNA and DNA.
$11 Billion Drugs 
Bio-IT World (Feb 13 2012) Discovery Informatics , Drug & Disease Targets 
Forbes | Forbes' posted a new estimate of how much it costs pharmaceutical companies to bring a new drug to market. The result: between $4 and $11 billion per drug, far more than any previous estimate.
 
 
 
Illumina's Numbers Without Roche 
Bio-IT World (Feb 13 2012) 
Motley Fool | Illumina has rejected Roche's most recent offer, and earlier in the week released fourth-quarter numbers that were a bit less than last year's, but still expected.
The State of Cloud Standards 
Health Data Management (Feb 10 2012) Bio-IT , IT Infrastructure 
As cloud computing adoption rates soar, standards groups see promise with establishing aligned interfaces, rules written into RFPs and SLAs, and harmonized government legislation.
Personalized Medicine Partnership Launches in Florida 
Bio-IT World (Feb 10 2012) Bio-IT , Discovery Informatics , IT Infrastructure 
Orlando Sentinel | Sanford-Burnham Medical Research Institute, Florida Hospital and Moffitt Cancer Center have teamed to create Personalized Medicine Partnership of Florida.
Supporting the $1000 Genome 
Bio-IT World (Feb 10 2012) Bio-IT , Clinical Trial Informatics , Discovery Informatics 
Forbes | With the $1,000 genomic sequencing barrier looming, the question remains whether we'll be able to make sense of the data to come pouring off sequencers like Life Technologies' new Ion Proton Sequencer.
Scientific Collaboration in New York 
Bio-IT World (Feb 9 2012) Bio-IT , Clinical Trial Informatics , Discovery Informatics 
Xconomy | The New York Genome Center will open this month, and the New York eHealth Collaborative held its first conference last year. It's been a season of collaboration for scientific organizations in the New York area.
San Diego Gets Bulk of California NIH Grants 
Bio-IT World (Feb 9 2012) 
San Diego Source | A new PricewaterhouseCoopers report shows that three of the top 10 California recipients of National Institutes of Health grants were in the San Diego area.
GSK $64 million Melbourne expansion 
Invest Victoria, Melbourne, Australia (Feb 9 2012) Business & Market Insights , Discovery Informatics 

GlaxoSmithKline has announced that it will invest about $64 million to expand its manufacturing and new drug development activities in Melbourne, Australia. The investment by one of the world’s leading pharmaceutical companies will create 58 new highly-skilled jobs by 2017.

Laying the Foundation for Next-Gen Cancer Diagnostics 
Bio-IT World (Feb 8 2012) Clinical Trial Informatics , Discovery Informatics , Drug & Disease Targets , Next-Gen Data 

Bio-IT World | This summer, Foundation Medicine will launch what could be described as the next generation of cancer diagnostics. The Cambridge, Mass.-based company, founded by a premier group of cancer researchers and funded by Third Rock Ventures, Kleiner Perkins Caufield & Byers and Google Ventures, will launch a comprehensive next-gen sequencing (NGS) profile screening some about 200 genes known to be clinically relevant and actionable in cancer using routine, formalin-fixed paraffin embedded patient cancer specimens.

Warp Drive Bio Charts Course for Natural Product Drugs 
Bio-IT World (Feb 8 2012) Clinical Trial Informatics , Discovery Informatics , Drug & Disease Targets 
Bio-IT World | While many major pharma companies have been cutting back their research into natural products, Warp Drive Bio, a new start-up out of Third Rock Ventures in Boston, is dedicated to mining the genome of micro-organisms for potent natural product compounds. And in a striking $125-million deal, Warp Drive has teamed with Sanofi to provide ample funding to get operations off the ground and potentially into orbit.
Red Hat Appliance Smooths Storage on Amazon Cloud 
Wired News (Feb 7 2012) Bio-IT , IT Infrastructure 
Open source vendor Red Hat today rolled out its Virtual Storage Appliance for Amazon Web Services, which it said "enables organizations to extend their datacenter storage to the cloud."
 
Modular Data Centers: Is Anyone Buying? 
Wired News (Feb 7 2012) Bio-IT , IT Infrastructure 
Is a data center built into a standard 20-foot shipping container on your shopping list, cloud service providers? That's the question some are asking as these portable data centers, pioneered by Sun with its Project Blackbox (later dubbed Sun Modular Datacenter, or Sun MD), enter their sixth year of commercial availability.
Apache Hadoop: What You Need to Know About This Important Big Data Tool 
Forbes.com (Feb 7 2012) Bio-IT , IT Infrastructure 
Apache Hadoop has been the driving force behind the growth of the big data industry. But what does it do, and why do you need all its strangely-named friends, such as Oozie, Zookeeper and Flume?
 
 
follow join 
 
New Complimentary Market Survey 
Collaborations and Communications Within Drug Discovery Research 
 
Sponsored by Accelrys 
This survey was conducted by the Cambridge Healthtech Media Group in January, 2012. Related to their HEOS initiative to gather valid information around externalizing collaborative research while improving communications in the cloud. With 310 qualified industry respondents the survey findings reveal useful usage and trends patterns. An insightful follow-on discussion and webinar related to this survey, and the HEOS by Scynexis SaaS portal is also available on the Bio-IT World website for complementary viewing. 


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