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Celera Pushes Boundaries with Automated Workflows 
Pathway Genomics Joins the Direct-to-Consumer Genomics Parade 
Editor’s Note: A Year of Tumult 
Short News & Analysis

Celera Pushes Boundaries with Automated Workflows
By John Russell

The use of leading edge informatics tools is part of Celera’s DNA. In the race to sequence the human genome, high performance computing and sophisticated home-grown informatics were as important as high speed sequencing machines to Celera’s success. Celera is hardly that company today, having redefined its mission to become a leader in diagnostics and “personalized disease management.” What hasn’t changed is its use of leading edge informatics.

While widespread adoption of automated workflow tools has been sluggish in life sciences – unlike many other industries - Celera has jumped onboard, building on its several-years-old relationship with workflow platform vender InforSense. Making sense of vast quantities of data has always central to Celera’s mission; today that generally means performing GWA studies and associated functional genomics work to identify and help validate biomarkers. More.


Pathway Genomics Joins the Direct-to-Consumer Genomics Parade
By Kevin Davies

Twenty months after the debut of consumer genomics pioneers 23andMe and deCODEme, San Diego-based Pathway Genomics has launched its own comprehensive direct-to-consumer genotyping service. Company founder and CEO James Plante says Pathway offers several key advantages over its competitors, including the depth, speed and security of the genotyping analysis on offer. More.


Top Story Last Issue
Editor’s Note: A Year of Tumult

By John Russell

If you think of the ‘business year’ as an annual race extending from Labor Day to roughly July 4 -  followed by a brief summer pause to reset for the next race – this year the economy trampled all other contenders. Budgets shrank. Clients retrenched. Untouchables weren’t. Whatever your plan of attack was on September 1, by January 1 it wasn’t. More.


Short News & Analysis

(Click for Full Briefs)

Genedata Refreshes Web Site
A new look is intended to streamline navigation through the site. Separately, the company announced a contract with Chugai..

Linguamatics Extends AstraZeneca License
AstraZeneca, a customer of Linguamatics since 2003, has extended its license to the I2E..

Merrimack Initiates Enrollment in MM-111 Phase 1/2 Study
MM-111 is the first bispecific antibody binding two different receptors on the same cell to enter clinical development..

Invitrogen Launches Resource for Cellular Technologies
Invitrogen says its Cell Resource Center Web portal brings together educational resources and the latest technologies..

DREAM4 Posts Final Challenge
The last challenge (Challenge 3) can be found at..

BioSeek in EPA’s ToxCast Program
EPA will use BioSeek technology to profile the biological effects of compounds in a second phase ToxCast program..

Optimata to Collaborate with Teva
The agreement is intended to efficiently rescue and redirect the clinical development of discontinued drug candidates..

(Click for Full Briefs)



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Next-Generation Sequencing: Solving the Genome

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Insight Pharma Reports
Bioinformatics and Computational Biology: Bottlenecks and Options
Author:  K. John Morrow, Jr., Ph.D.

Bioinformatics and Computational Biology: Bottlenecks and OptionsThe interdisciplinary fields of Bioinformatics and Computational Biology are locked in a high stakes race with analytical instrument developers and innovators. The pace and scope of change in many fields of biomedical research rivals what we once associated only with semiconductor devices.  Bioinformatics and Computational Biology: Bottlenecks and Options presents an analysis of the state of the field in terms of the current systems biology models and their applications, where the field is headed and the possible implications for applied biological science.  Read more.



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Biomarkers: An Indispensible Addition to the Drug Development Toolkit

Examining the Potential of Biomarkers.  This white paper provides insight from experts in industry and academia, and explores the role of biomarkers as evaluative tools in improving clinical research and the challenges this presents. Download the paper.  (Sponsored by Thomson Reuters)

Scientific Data Lifecycle Management: Preparing for Storage in an Uncertain Future
Help your organization maintain control over vast and overwhelming streams of data and prepare for the future of sequencing through this informative paper. Download the paper    (sponsored by BlueArc)

Managed Innovation, Assured Compliance
Developing, executing and managing the transformation, analysis and submission of clinical research data with SAS® Drug Development.
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What’s Wrong with Biomarkers?
No one doubts biomarkers’ long-term value, but many obstacles remain. Read this in-depth analysis in which distinguished experts examine biomarker challenges, failures, barriers, and need for standards. 
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Protecting Intellectual Property 
In this white paper we explore the issues facing patent creation and defence in the electronic age and discuss the tools and functionality required to protect innovation.  Access the Paper (sponsored by IDBS)

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NEW! Life Science Webcasts from Bio-IT World and Cambridge Healthtech Media Group
Life Science Webcasts
Chris Dagdigian Talks Trends
At the Bio-IT World Conference & Expo, Chris Dagdigian talked about the old news, breaking news, and future of bio-IT. Get his perspective on what's overhyped and what's worth the buzz. View the webcast.

The Future of Personal Genomics
An expert panel candidly discussed the future of personal genomics and what that means for both companies and consumers at the Bio-IT World Expo. Clifford Reid (Complete Genomics), Philip Reilly (3rd Rock Ventures), Dietrich Stephan (Navigenics), Robert Green (Boston University), John Halamka (Harvard Medical School), and Jorge Conde (Knome), give their unique perspectives on how this emerging industry could change medicine. View the webcast. 

Boguski's Resounding Health
Mark Boguski is launching a new direct-to-consumer Internet search firm called Resounding Health and he tells Bio-IT World Editor, Kevin Davies, all about it. His goal is to create value-adding process networks to provide the most cost-effective management of chronic diseases in the near future. View the webcast.

Open Source Models for Personalized Medicine
Through the company he founded, CollabRx, Jay Tenenbaum aims to leverage the extraordinary untapped expertise and resources across the industry to empower individual patient health care through personalized research. View the webcast.


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Cambridge Healthtech InstitutePublished by Cambridge Healthtech Media Group, division of CHI, Copyright © 2009; All rights reserved. Predictive Biomedicine may not be reproduced, electronically or in print, by any means, mechanical or electronic, in whole or in part, without written permission of Cambridge Healthtech Media Group, 250 First Ave., Suite 300, Needham, MA, 02494. 
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