Short Courses* 

Monday, August 19

9:00 am - 12:00 pm

SC1: Mapping Genomes in 3D

Genomes are organized into 3-dimensional (3D) conformation in vivo through interactions with protein factors. In addition, DNA elements separated by long genomic distances are known to functionally interact. However, the details of these 3D structures and their role in gene transcription are largely unknown. This course is designed to provide an overview of sequencing strategies and analysis for probing the 3D structure of genomes.

Instructors to be Announced

SC2: Sample Prep

The emergence of next-generation sequencing technologies has revolutionized genomic research. This dramatic advancement, however, still involves complicated and labor-intensive workflows for upstream sample preparation, library construction, and template amplification. Instructors share their solutions to prepare for sequencing runs (including the specific requirements of sequencing platforms) by addressing customizability, compatibility, and cost effectiveness.

Stacey M. Broomall, MS, Laboratory Manager, ECBC Genomic Sciences Team, U.S. Army, BioSensors Branch, Edgewood Chemical Biological Center

Additional Instructors to be Announced

Tuesday, August 20

6:00 - 9:00 pm

SC3: Assembly and Alignment

The most important first step in understanding next-generation sequencing data is the initial alignment or assembly. This course is designed to provide an overview of alignment and assembly algorithms, and comparisons for various applications.

Gabe Rudy, Vice President, Product Development, Golden Helix and Author, “A Hitchhiker’s Guide to Next Generation Sequencing”

SC4: Cancer Genetics and Epigenetics

Sequencing has enabled comprehensive and integrative analysis of cancer as initiation and progression are driven by a series of genetic and epigenetic alterations. Genomic profiling and analyses are now possible from small amounts of tissue or even single cells, allowing heterogeneity to be addressed at the regional and cellular level. This course is designed to provide insights into the genomic and epigenomic sequencing strategies and analysis for cancer.

Instructors to be Announced

*Separate Registration Required