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Horizons

January 13, 2003 | The Mirus Genomic Index, prepared exclusively for Bio·IT World, is calculated as the sum of the market capitalizations of all included companies and is consequently a value-weighted index. It serves as an indicator of the financial health of the industry. The index was developed at RCW Mirus (www.merger.com), an investment banking firm, by David Hoffer and colleagues at the firm's Boston headquarters.

Discovery Companies
Company Market  Revenues  Net Income 
Cap1 TTM2 TTM2
Celera Genomics (CRA) 811.7 117.3  (215.8)
CuraGen Corp. (CRGN) 261.4 20.0  (77.7)
deCODE Genetics Inc. (DCGN) 138.1 42.5  (124.3)
Deltagen Inc. (DGEN) 32.8 15.4  (101.0)
DNAPrint Genomics (DNAP.OB) 12.2 0.1  (3.5)
Exelixis Inc. (EXEL) 465.3 44.6  (83.5)
Genome Therapeutics Corp. (GENE) 42.0 26.1  (33.1)
Human Genome Sciences (HGSI) 1367.4 3.4  (215.1)
Hyseq Inc. (HYSQ) 21.7 30.0  (39.9)
Incyte Genomics Inc. (INCY) 374.8 135.3  (214.5)
Interleukin Genetics Inc. (ILGN) 14.3 0.1  (5.4)
Lexicon Genetics Inc. (LEXG) 212.0 35.4  (56.8)
Millennium Pharmaceuticals (MLNM) 2935.4 310.9  (577.5)
Myriad Genetics Inc. (MYGN) 514.1 56.2  (18.1)
Oxford GlycoSciences (ADR) (OGSI) 125.0 16.1  (58.2)
Rigel Pharmaceuticals Inc. (RIGL) 69.6 16.9  (35.0)
Sequenom Inc. (SQNM) 89.4 34.0  (171.9)
Vertex Pharmaceuticals (VRTX) 1403.6 168.8  (79.9)
Q4 2002 Index = 8,891

Tools Companies
Company Market  Revenues  Net Income 
Cap1 TTM3 TTM3
Aclara Biosciences (ACLA) 86.4 2.8 (37.1)
Affymetrix Inc. (AFFX) 1616.5 276.6 (13.0)
Applied Biosystems Group (ABI) 4604.8 1633.1 154.0 
Ciphergen Biosystems (CIPH) 94.2 33.0 (29.5)
Compugen Ltd. (CGEN) 36.5 11.5 (13.1)
Epoch Biosciences Inc. (EBIO) 41.6 9.8 (4.2)
Harvard Bioscience Inc. (HBIO) 102.0 50.4 1.3 
Illumina Inc. (ILMN) 162.5 7.0 (40.9)
Invitrogen Corp. (IVGN) 1447.8 640.1 1.9 
LION Bioscience AG (ADR) (LEON) 48.7 34.1 (146.6)
Luminex Corp. (LMNX) 146.1 15.3 (21.7)
Qiagen N.V. (QGENF) 951.5 291.3 32.3 
Third Wave Technologies (TWTI) 86.5 30.7 (57.2)
Transgenomic Inc. (TBIO) 68.1 39.0 (14.8)
Varian Inc. (VARI) 1074.5 779.9 51.6 
Q4 2002 Index = 10,568

1) Market cap is number of shares outstanding x share price as of Nov. 29, 2002 (in $ millions).

2) TTM is trailing 12 months ending September 30, 2002, for all companies except Oxford GlycoSciences, for which TTM ends June 30, 2002 (all financials in $ millions).

3) TTM is trailing twelve months ending September 30, 2002, for all companies (all financials in $ millions).

RCW Mirus Inc. does not assume any liability for errors or omissions.

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