The route from gene to drug via high-throughput protein structure determination could ultimately yield thousands of structures a year.
 1 DNA from humans and other organisms is the starting material for analysis.
2 Bioinformatics techniques are used to identify genes likely to be involved in disease pathways.
3 Molecular biology techniques are used to clone genes, express, and purify protein.
4 Crystals of purified protein are grown at high throughput.
5 Protein crystals are analyzed using X-ray beams at a synchrotron radiation source.
6 The 3-D structure of a protein is solved using computational techniques.
7 The protein structure enables better drug discovery by revealing the way a potential drug interacts with the protein.
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ART BY STRUCTURAL GENOMIX INC.
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