As toxicogenomics becomes more widely adopted and applied at higher throughput, it will have an impact on the continuum of drug discovery and development.
· Perform routine toxicogenomic screening using in vitro and/or in vivo assays
Lead Prioritization
Lead Optimization
Pre-Clinical Safety
PI
P2 Clinical
PIII
· Perform routine toxicogenomic mechanism of toxicity using in vitro and/or in vivo assays
· Discover biomarkers
· Identify blood markers
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