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COVER STORY
Antiquated reporting of adverse events in clinical trials is costing pharma billions — and forcing it to seek new pharmacovigilance solutions.
By Mark D. Uehling
STRATEGIC INSIGHTS
INTELLECTUAL PROPERTY · Considered one of the most important patent decisions in history, the Supreme Court’s Festo ruling has great significance for biotech inventions.
By Murray Spruill and Kathryn Coulter
INTELLECTUAL PROPERTY · Patents, so critical to encouraging investment in developing new technologies, threaten to become a legal and economic minefield that could prevent effective commercial exploitation of genomics.
By David P. Lentini and Stephen A. Bent
SOURCEBOOK: Microarrays
Insightful Corp.’s Michael O’Connell discusses the importance of statistical rigor when analyzing data from microarrays. Plus: a directory of microarray-related vendors.
By John Russell
| Business+Strategy |
IT+Informatics |
HIGH-PERFORMANCE COMPUTING · Paracel's gone, but users who need speed-boosting gear have a variety of alternatives
DRUG DEVELOPMENT · Three companies reveal innovative uses of technology and data as key to their success
MARKET COMPASS · Only a slight dip for discovery companies, but tools providers took a hit in Q3
Insights | Outlook · Biobanks should be especially vigilant with regards to hacking attacks.
By Michael Swenson
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SCIENTIFIC COMPUTING · 64-bit processors, more memory provide boost for handling 3-D volumes, huge data sets
COMPANY TO WATCH · De Novo Pharmaceuticals identifies novel compounds — right before your eyes.
CONVERSATION · Research director David Mount on his new book, sequence analysis, and teaching bioinformatics
Inside the Box · Providing a middle ground between the command line and the Web
By Chris Dwan
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| Science+Technology |
In Every Issue |
SEQUENCING · Conference control passes from TIGR to Venter Institute, but sequencing technology continues marching on
CONVERSATION · Mary-Claire King discusses breast cancer research, complex traits, and human rights.
LAB SYSTEMS · Vendors try to make labware sing, adding ERP, multiplatform, and project-management features
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First Base | Using DNA technology to help the victims of human rights abuse.
By Kevin Davies
The Russell Transcript | New data offer a glimpse into the year ahead.
By John Russell
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