CONTENTS: DECEMBER 2003

By BIO-IT World
December 15, 2003

Features

Model Patient
The pharmaceutical industry remains cautious about computer simulation of clinical trials.
By Mark D. Uehling

Scenes from a Cell
Breakthroughs are making cell-based screening faster, easier, more powerful.
By Malorye A. Branca



Special Issue 
· Strategic Insights :
Intellectual Property & The Law
· When Patents Persist
BY Douglas J. Kline and Duncan A. Greenhalgh
· The Hidden Costs of 'Free Software'
BY Steve Henry and Liza Vertinsk
· Patenting Bioinformatics Tools
BY Dianne M. Rees and John E. Ottaviani
News·Analysis 
Why Drugs Fail
FDA Guidance: More Questions Than Answers
High-Speed Computing: Clusters, FLOPS, Creativity
C-Sixty Pitches Buckyballs for Drugs
A Diagnostics Dream Team
Big Pharmas Sign Deals with GeneCards
Quick, to the GeneCave!
MIT Researchers Win a GRAM(Y)
Pathway Pandemonium
Unbreakable vs. Disposable



Horizons

David Botstein: Learning the Language of Systems Biology
Geneticist par excellence on the importance of integrated science.
Interview by Zachary Zimmerman

Diamond in the Desert
Impressive research budgets, pharma talent, and a prodigal son build a biotech oasis in Phoenix.
By Mark D. Uehling


Columns 

First Base | Kevin Davies
FDA guidance on the road to genomic medicine.


Nothing Ventured... | Michael A. Greeley
Minuscule devices promise big opportunities.


Fully Equipped | By Robert M. Frederickson
Putting a new spin on the proteomics lab.


The Dodge Retort | By John Dodge
An ego-less model for research and innovation.


Departments

New Products
Velocity11 delivers microplate systems · Biocept introduces 3-D microarrays · Accelrys ports apps to Linux
 
White Papers & Special Reports

thomson reuters image
Biomarkers: An Indispensible Addition to the Drug Development Toolkit
Examining the Potential of Biomarkers
Sponsored by Thomson Reuters

Biomarkers are becoming an essential part of clinical development. In this white paper, Thomson Reuters provides insight from experts in industry and academia, and explores the role of biomarkers as evaluative tools in improving clinical research and the challenges this presents.

Discover the potential of biomarkers to:

  • Improve decision making
  • Accelerate drug development
  • Reduce development costs


BlueArc_Scientific Data
Scientific Data Lifecycle Management: Preparing for Storage in an Uncertain Future
Sponsored by BlueArc

Managing vast and overwhelming streams of gene sequencing data today requires ultra-high performance systems and processes. With continued rapid advancement and improvements in gene sequencing, expect tomorrow’s instruments to output quantities of genomic information that will dwarf current levels. Help your organization maintain data control and prepare for the future of sequencing through this informative paper that discusses:

  • The information technology challenges of gene sequencing
  • “Intelligent” methods for data management and customization
  • System survival tips... Deciding what data to keep or delete
  • New tools to keep scientists ahead of impending data torrents


SAS Managed image
Managed Innovation, Assured Compliance
Developing, executing and managing the transformation, analysis and submission of clinical research data with SAS® Drug Development
Sponsored by SAS
Get better products to market faster. Download this white paper to discover the top ten challenges facing life science executives and how to overcome them. See how SAS Drug Development transforms clinical data into true innovation.


Life Science Webcasts & Podcasts

Presented by Trade Commission of Spain

Spain Biotech: An Engine for Economic Change 

TCS podcastDiscover how Spain is focusing on biotechnology to be an engine for economic change through gradual internationalization, development and technology transfer.

Regional governments are actively investing in public and private biology research and promoting the creation of knowledge-based companies. Spain’s human capital combined with aggressive investment in biotech research and infrastructure has led to the creation of bio-clusters.

Today, there are nearly 700 Spanish companies engaged in biotechnology, with almost 50 percent growth in funding devoted to research. In fact, spending on internal R & D in biotechnology has grown 46 percent and is close to 300 million Euros.

Access the podcast 

 



More Podcasts

Job Openings

saic_logo

MANAGER, SCIENTIFIC COMPUTING & PROGRAMMING
(Bioinformatics Manager)
SAIC-Frederick, Inc has an exciting opportunity for a Manager, Scientific Computing & Programming - Core Genoytyping Facility in Gaithersburg, Maryland.  In this role, you will lead the Bioinformatics & Analysis Group.
Master’s or equivalent required.  PhD preferred. Six years experience in development of scientific programs in high-performance computing environment including five years supporting scientific research in computational chemistry, biology, or genetics, & two years supervisory experience.  View complete job posting & apply: www.saic-frederick.com. Position #146945.

For reprints and/or copyright permission, please contact The YGS Group, 1808 Colonial Village Lane, Lancaster, PA;

(717) 399-1900 ext. 125, or via email to Ashley.Zander@theYGSgroup.com.