LIMS/Automation Software Developer – NGDx


LIMS/Automation Software Developer – NGDx
Novartis Institutes for BioMedical Research (NIBR)
USA – Cambridge, MA

Type: Permanent
Rate: Competitive
Qualification: PhD
Number of Positions: 1
Reference: 113142BR


Description: 


We are seeking a highly motivated software developer to join the Novartis Next Generation Sequencing Diagnostics (NGDx) Team. The successful candidate must be self-directed and highly collaborative. The candidate will:

  • Assist in the process of evaluating LIMS solutions from a variety of vendors
  • Design and implement LIMS/workflow execution  support from sample accession thru NGS analysis
  • Work with lab users to define LIMS & workflow requirements
  • Participate in the technical development process for genomics platforms , including next-generation sequencing platforms
  • Work with automation team and lab users to implement lab automation


Specific Job Duties 

  • Design and implement pre-defined laboratory and informatics  workflows within the LIMS
  • Modify and update workflows based on protocol improvements
  • Work with automation team to integrate lab automation into LIMS/workflow
  • Design, develop and configure diverse laboratory instruments from vendors
  • Evaluates product enhancements and capabilities, in addition to implementing upgrades as required.
  • Ensure that projects are developed in accordance to regulatory standards and departmental SOPs.
  • Follow best practices for software version control, testing and release engineering.
  • Train biologists and other lab staff on how to use LIMS.
  • Provide status updates in regular team meetings
  • Attend technical workshops and conferences related to software development and bioinformatics
     

Essential Skills: 

  • B.S. in Computer Science or a related scientific or technical field (or equivalent experience) and a minimum of five years related experience.
  • Knowledge of and experience with commercially available LIMS solutions (LabVantage , CoreLIMS, StarLIMS, etc.) and a proven track record of integration and deployment.
  • Experience in creating new templates/workflows, modifications to existing logic/calculations, and interfacing with external instruments and applications.
  • Experience working closely with end users and providing assistance to debug problems in production environments.
  • Demonstrated experience with one or more of the following programming languages: Java, C#, Python, Perl, C#, C++, Ruby
  • Demonstrated experience with database programming and interfaces, preferably in MySQL or Oracle.
  • Used SVN, GIT or similar version control systems.

 

Desired Skills: 

  • Experience working in a regulated environment, CLIA. GLP & 21 CFR Part
  • Demonstrated experience with software lifecycle tools, continuous integration, source control, test coverage etc.
  • Demonstrated experience in providing support for production software systems.
  • Experience developing web-based GUI.
  • Experience working with scientific users

About Novartis Institutes for BioMedical Research (NIBR)

The Novartis Institutes for BioMedical Research is the global pharmaceutical research organization for Novartis. The NIBR research network is comprised of more than 6,000 scientists, physicians, and business professionals working together across 10 locations around the world to discover innovative medicines that treat diseases with high unmet medical need. Novartis employs more than 2,000 associates in Cambridge, making it the city’s largest private employer and ideally situated in one of the leading life science communities in the world.

NIBR conducts research globally with sites in Emeryville, California; Cambridge, MA; East Hanover, NJ; Basel, Switzerland; Horsham, UK; and Shanghai, China.


About the Next Generation Sequencing Group:
 

The ability to sequence each patient’s genome in great detail, quickly and inexpensively, is changing the practice of medicine. At NIBR, we are dedicated to the development of therapies that improve clinical outcomes for patients. Next generation sequencing and other cutting-edge molecular characterization technologies will be important tools for discovering breakthrough therapeutics, and for delivering the right medicines to the right patients.
NIBR is launching a new Next Generation Diagnostics (NGDx) group at our global headquarters in Cambridge, MA.  The NGDx team will leverage cutting-edge technologies such as next generation sequencing for characterizing human tissues, by individual lesions and by pathway signatures relevant to therapeutic response.  The goal is to develop a robust and comprehensive molecular profile for each patient. To this end, the group will begin by developing capabilities to characterize therapeutically relevant genetic lesions and pathway signatures in human cancer.
Opportunities exist for genomics scientists, computational biologists, bioinformatics scientists, software and systems engineers, assay development scientists, histopathologists, sample technicians, and biochemists.

 





For reprints and/or copyright permission, please contact  Jay Mulhern, (781) 972-1359, jmulhern@healthtech.com.