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Dear Colleague,
Welcome to this week's eNewsletter covering breaking R&D news, business insights, and a webcast with Vertex CEO Joshua Boger.
 

 
 
BREAKING R&D NEWS
 

Scientists Define 21 New Genes Associated with Crohn's Disease
NIH News [July 21] An international consortium of researchers has identified 21 new genes for Crohn’s disease. This discovery brings the total number of known genes associated with Crohn’s disease to more than 30 and advances understanding of causes and potential avenues to develop new treatments. More.

Making Genetic Testing Useful
MIT Technology Review [July 22] A new $31 million project that will revisit large epidemiological studies could have a broad impact on public-health recommendations and could also provide new targets for drug development. More.

Allen Institute Releases First Data for Spinal Cord Researchers, Unveils New Financing Model
Xconomy [July 17] The Allen Institute for Brain Science is releasing a cellular map on its website that shows 2,000 genes at work in the mouse spinal cord for the first time. More.

Pfizer Inks Global License to Genomatix Software
Press Release [July 15] Genomatix Software, Inc.  the US branch of Munich (Germany) based Genomatix Software GmbH, announced that it has reached an agreement with Pfizer Pharmaceuticals to provide Genomatix software and data content to Pfizer sites across the globe. More.

 
 
BUSINESS INSIGHTS 
 

Roche Acquires Private U.S. RNAi Company
Reuters [July 22] Roche Holding said it has acquired Mirus Bio Corp, a privately held U.S. company that focuses on RNAi or gene silencing as a way to fight disease, for $125 million (62.4 million pounds). More.

Making Genentech Disappear
Forbes [July 22] Roche's offer to buy the 44% of biotech bellwether Genentech that it does not already own could dramatically change the landscape of the U.S. biotechnology industry. More.

David de Graaf Leaves Pfizer for Boehringer-Ingelheim
Bio-IT World [July 16] Roughly three years after becoming Pfizer’s first director of systems biology, David de Graaf is leaving to become the VP of Biotherapeutics and Integrative Biology at Boehringer-Ingelheim. More.

Genzyme, PTC in $100M Deal for Cystic Fibrosis, Muscular Dystrophy Therapies
Boston Business Journal [July 14] Genzyme Corp. has inked a $100 million development deal with a New Jersey biopharmaceutical company to develop and sell a new treatment for genetic diseases. More.

 
 
 

LIFE SCIENCE JOBS

Lilly Singapore Center for Drug Discovery (LSCDD) - Associate Director of Informatics,
Lead and mentor a strong team for the Bioinformatics group at the Integrative Computational Sciences (ICS) department at LSCDD towards the development of novel algorithms, data analysis methods and software tools for drug discovery. Work closely with the Software Engineering group at ICS, and collaborate with the Discovery IT organization in Europe and USA. For additional information, or to apply visit:
 LSCDD

Lilly Singapore Center for Drug Discovery (LSCDD)- Senior Bioinformatics Scientist,
Contribute to the development of novel algorithms, data analysis methods and software tools for drug discovery as part of the Integrative Computational Sciences (ICS) department at LSCDD.  Work closely with informatics and software engineering peers at ICS, and collaborate with the Discovery IT organization in Europe and USA. The successful candidate will offer hands-on insight and expertise in tailored therapeutic informatics and statistical analyses at the post-genomic era. For additional information, or to apply visit:
 LSCDD   

Lilly Singapore Center for Drug Discovery (LSCDD) - Manager, Software Engineering (Integrative Computational Sciences)
Join the Integrative Computational Sciences (ICS) department at Lilly Singapore Centre for Drug Discovery (LSCDD),as Manager Software Engineering.  Lead the development of integrated applications to process and visualize data from cutting edge technologies used by scientists at Lilly Research Labs (LRL) and the Drug Discovery Research (DDR) teams. Masters in Computer Science/Engineering or related discipline, 10+ years post graduation experience , 2 years management experience needed. For a complete job description and requirements or to apply visit: LSCDD 

Lilly Singapore Center for Drug Discovery(LSCDD) -Senior Software Engineer, 
Join a strong team of software engineers in our Integrative Computational Sciences (ICS) at LSCDD. Collaborate with, and help develop integrated applications to process and visualize data from cutting-edge technologies used by scientists at Lilly Research Labs (LRL) and the Drug Discovery Research (DDR) teams. The Software Engineering team provides computational tools and tailored software solutions that enable the global effort of Tailored Therapeutics; ‘The Right Drug, at The Right Dose for The Right Patient at The Right Time'. For additional information, or to apply visit:
 LSCDD  

Linguamatics, Applications Specialist, Life Sciences Text Mining Software - Northeast U.S.*
Linguamatics, a leader in semantic search and text mining for the
pharma/biotech industry, is looking for an experienced life science
focused applications specialist to demonstrate the value of our products and help drive the growth of our North American business.  For further information visit: www.linguamatics.com

Memorial Sloan-Kettering Cancer Center - Linux Systems Administrator 
MSKCC Bioinformatics Core in Manhattan seeks Linux Systems Administrator. Install, configure and update monitor and troubleshoot HPC cluster, email and web servers.  Master's degree and 5 years experience with HPC, network security, Postfix, Apache, Tomcat, Grid Engine. Solaris, Email
 bicjobs@cbio.mskcc.org or www.mskcc.org #015429. EOE/AA 

Unilever - Mathematical Modeller (Research Scientist)
This research is leading to the requirement for integration of both biological and chemical data that may not be amenable to analysis through traditionally used techniques. The ability to work in multidisciplinary teams alongside biologists, chemists and statisticians plus enthusiasm for learning new science is critical for the role.   For a complete job description and to apply, please visit:
 https://unilever.recruitmax.com/ 

More Life Science Jobs ~ Add a Job Listing

 

FEATURED EVENTS 

ELNs: Advanced Laboratory Solutions-September 15 - 17 2008 • Crowne Plaza, Brussels, Belgium 

Discovery Knowledge & Informatics - September 15 - 17, 2008 • Crowne Plaza, Brussels, Belgium 

Multiplexed Genomics Tools: Targeting the Missing Links
Between Health and Disease
 - September 21-23, 2008 •
 Providence, RI

Next-Generation Sequencing Data Analysis -September 22-23, 2008 • Providence, RI

Barnett Educational Services, 2008 Schedule

To have your event featured here, contact Lynn Cloonan for more information.

 Email to a Friend 

CEO PERSPECTIVE

Drug Discovery, Development and Commercialization: Evolving Challenges and Opportunities 

Joshua Boger, PhD, president and CEO, Vertex Pharmaceuticals Inc., delivers his keynote address titled “Drug Discovery, Development and Commercialization: Evolving Challenges and Opportunities” at the 2008 Bio-IT World Conference & Expo, April 2008.  View the webcast.

EXCLUSIVE WEBCAST

NEW! Life Science Webcasts from Bio-IT World and Cambridge Healthtech Media Group

Life Science Webcasts

Bio-IT World Expo
Video Highlights

Personalized Genetics: Advancements and Driving Change
Linda Avey, co-founder of 23andMe, delivers her keynote at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008.
View the Webcast Now.

The Future of Personal Genomics
A distinguished panel of personal genomics experts discuss the future of personal genomics at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008.  They include Dietrich Stephan (co-founder, Navigenics); George Church (Harvard Medical School);
Jeff Drazen (editor-in-chief, New England Journal Medicine); Fred Ledley (Bentley College); John Halamka (CIO, Harvard Medical School); and Linda Avey (23andMe). Bio-IT World Editor-in-Chief Kevin Davies moderates the discussion.
View the Webcast Now

Insight Pharma Reports

Antibiotic R&D: Resolving the Paradox between Unmet Medical Need and Commercial Incentive

In-depth analysis of factors driving antibiotic R&D, the opportunities, scientific challenges, economic & regulatory realities, select compounds in clinical development. More Information

Custom Market Research Services
Our experienced research team will work with you to fully understand your needs in order to create and conduct a custom market research program that meets your objectives.
Learn More

Featured Content

Spain’s Emerging Biotech Revolution
The biotechnology sector is growing 10 percent faster in Spain than it is in the U.S. Driven by a culture, government and private sector that are open-minded and optimistic, Spain-based companies are emerging as leaders in this dynamic field. Discover how your business can capitalize on creative solutions from Spain-based enterprises. Download Now     
 


Will Healthcare IT Trends Standardize?
A new wave of activities are driving transformation within the healthcare market. One solution is found in a guide to PDF Healthcare Best Practices. This “Best Practices Guide” describes Portable Document Format (PDF) attributes and use to facilitate the capture, exchange, preservation and protection of healthcare information. This webinar will focus on trends in today’s healthcare market, the challenges in overcoming these issues, and finally how to use best practices to improve patient care, enhance productivity and eliminate paperwork. It’s hosted by Adobe and moderated by Digital Healthcare & Productivity Executive Editor, John Russell. Click here...  


Waters

Automate Method SOPs for Greater Efficiency and Fewer Errors with Waters® NuGenesis® Intelligent Procedure Manager
The Waters® NuGenesis® SDMS Intelligent Procedure Manager is a workflow software package designed to guide the laboratory analyst through a routine, comprehensive method standard operating procedure (SOP) and integrate results with a chromatography data system. The Intelligent Procedure Manager addresses the predominately manual activities required to perform an analytical method or test, reducing cycle times up to 50-75% as compared to a traditional paper trail with fewer opportunities for human error.  From late-stage development to final product quality control and lot release, Intelligent Procedure Manager can be applied to any lab environment where rigorous adherence to approved test methods and SOPs must be followed, including compliance requirements for cGMP operations.Download Now


This Bio•IT World Briefing On “Next-Generation Sequencing,”underwritten by GenomeQuest, Inc.,

presents a selection of feature stories, interviews,commentaries, conference reports, and editorials on the emergence, opportunities, and challenges posed by high-throughput sequencing. Covered in this collection: the launch of new platforms from Applied Biosystems and Helicos; new applications of nextgen sequencing; the rise of personal genomics; and informatics solutions to vexing problem of managing the vast volumes of next-gen data. Download now 

To have your white paper featured here, contact Lynn Cloonan for more information.


Cambridge
                                Healthtech InstitutePublished by Cambridge Healthtech Institute (CHI). Copyright © 2008, all rights reserved. No material may be reproduced electronically or in print without written permission from CHI, 250 First Ave., Needham, MA 02494-2814. For reprints and/or copyright permission, please contact The YGS Group, 1808 Colonial Village Lane, Lancaster, PA; 17601 717-399-1900 ext.110, or email: becky.mullaney@theYGSgroup.com