February 8, 2012
| Bio-IT World > Full Text Firewall


Full Text Firewall



Oct. 16, 2006 | One of the biggest stumbling blocks to the success of text mining remains the firewall that surrounds full-text archives. "It is the restricted access to the full text of papers and to citation information, rather than the technology, that is currently the greatest limitation, despite some encouraging open-access initiatives," EMBL bioinformaticist Peer Bork and colleagues wrote in Nature Reviews Genetics earlier this year.

Access to the full text often requires exorbitant subscriptions to publishing powerhouses such as Elsevier, Wiley, and others. The open-access movement, which fueled the launch of the Public Library of Science in 2002, has persuaded some publishers to partially open their archives - but most new papers remain off limits to non-subscribers.

Some of QUOSA's customers have done benchmarking, including one whom MacKenzie says compared full-text versus abstract text mining for protein-protein and protein-drug reactions, and retrieved 25-100 times more useful factoids out of full-text sources. Would more publishers going the open-access route reduce the need for QUOSA? "Open access is just another silo through which you get journal access," says MacKenzie. "The better access there is to full articles, the more people can take advantage of what we do."

Nature Publishing Group (NPG) recently announced an interesting experiment - an effort to enhance machine access to full text literature by proposing a standard content annotation called the Open Text Mining Interface (OTMI), which was first presented by NPG web publishing director Timo Hannay at Bio-IT World's 2006 annual conference.

The XML format of OTMI reorders each paper's sentences alphabetically, rendering the product unreadable to humans while allowing full-text searching of intact sentences. It's what Hannay calls "a potential compromise between business needs and open access." Hannay says he hopes all publishers will adopt OTMI or a similar standard to open up the entire literature for text mining.

One fan is Tim O'Reilly, who says, "It immediately struck me as 'slap your forehead brilliantly obvious...' I love the cleverness of this approach, which lets machines make use of the content in ways that human readers can't. I like it. You might consider it a "copyright hack.' "

Hannay says there's been considerable early interest from other publishers and text-mining researchers. This fall, NPG will roll out OTMI files for much of the Nature archives and encourage people to play with it. NPG is also launching a collaborative website to open up development of the specification and share tools. "Ideally, we want OTMI to become a de facto community standard (and perhaps in time a more formal standard). NPG has no desire to 'own' it," says Hannay. -- K.D.

Return to main article.

 

 

Click here to login and leave a comment.  

0 Comments

Add Comment

Text Only 2000 character limit

Page 1 of 1



White Papers & Special Reports

sgi whp 2
Managing the Modern Genomics Data Flood
Sponsored by SGI

Managing and storing the perfect storm of multi-disciplined data pouring from next generation sequencers and other omics instruments is a central challenge in life sciences. Discover in this paper how the SGI ArcFiniti storage solution, optimized for unstructured genomics and life sciences data can: 

  • Reduce costs, proactively protect data integrity, and deliver the high performance I/O required for genomics data processing and analysis.  
  • Effectively manage capacities from 156TB to 1.4PB as a disk based, integrated hardware and software platform 


sgi - whp 1
Turning Genomics Data into Practical Insight
Sponsored by SGI

With worldwide sequencing capacity approaching 13 quadrillion DNA bases annually turning genomics data into knowledge is a true computational challenge. Read this paper and learn how the SGI UV coherent shared memory platform can:  

  • Speed results time while cost competitively tackling the most difficult computational problems across all omics disciplines. 
  • Push performance by scaling to extraordinary levels, up to 256 sockets (2,560 cores, 4,096 threads) per single system (one OS image). 

Provide support for up to 16TB of coherent shared memory in a single system image enabling extreme efficiency across a wide range of compute demands. 



accerlys-logo_2012_wh
New Complimentary Market Survey…
Collaborations and Communications Within Drug Discovery Research
Sponsored by Accelrys
This survey was conducted by the Cambridge Healthtech Media Group in January, 2012. It was sponsored by Accelrys related to their HEOS initiative to gather valid information around externalizing collaborative research while improving communications in the cloud. With 310 qualified industry respondents the survey findings reveal useful usage and trends patterns.  An insightful follow-on discussion and webinar related to this survey, and the HEOS by Scynexis SaaS portal is also available on the Bio-IT World website for complementary viewing.
 


Job Openings

tessella logo 
Scientific Software Engineer
Boston MA
$70,000 to $95,000
 

Tessella delivers software engineering and consulting services to leading pharmaceutical and biotech companies. We are recruiting Software Engineersto work with skilled bioinformaticians and scientists to identify business needs and recommend and develop technical solutions. Applicants require BS, MS or PhD in bioinformatics, biology or chemistry and 2+ years of software development in either: Java, C#, C++, C or VB.NET. 

Apply at http://jobs.tessella.com   

 

oxford nanopore logo 


 Early Access Collaborations Managers
Oxford Nanopore Technologies is developing a novel technology, GridIONTM for the direct, electronic analysis of DNA/RNA and other analytes.  As the system approaches the market, we are building a team of technically knowledgeable, highly motivated candidates with excellent customer service and facilitation skills to join our company as Collaboration Managers.  This is a unique opportunity to work with world-leading genomics customers throughout the early adoption phase of a new generation of DNA sequencing technology.. This is a facilitative, enabling role with responsibility for managing technology development collaborations with key customers at leading genomics institutions.  It will include long term management of the collaboration plan and milestones and associated meetings and documentation. Click here to find out more and apply   

Oxford Nanopore's GridION technology, VP, Sales and Marketing Oxford Nanopore Technologies is a fast-moving technology company that is developing a novel electronic molecular analysis technology. The technology is adaptable for the analysis of DNA/RNA, proteins, chemicals and other molecules.  It is therefore suitable for use in a variety of markets including scientific research and clinical applications.  As the technology approaches the market, Oxford Nanopore is seeking a visionary VP of sales and marketing to join the senior team.  The candidate will embrace the opportunities afforded by entering the market with a truly disruptive technology that has the potential to expand the number of users and the variety of applications in each target market.  This is a rare opportunity to influence the commercial strategy at an early phase of its commercial lifetime, in a well funded company.  Oxford Nanopore welcomes applications from candidates with a track record of high-level strategic commercial  leadership, who wish to apply a fresh approach to existing markets.  Experience in Life Sciences/DNA sequencing is central to this role, however we will consider your application if you have experience of disruptive technologies in other related industries.  We are particularly interested in candidates with strong expertise in the use of digital technologies for sales and marketing of scientific/technical products.  Click to  Apply  


 

For reprints and/or copyright permission, please contact  Tim McLucas, (781) 972-1342, tmclucas@healthtech.com .