London Calls for Gene Codes Forensics Database


By Melissa Kruse Bio-IT World

Last March, the United Kingdom contracted with the software company Gene Codes to use its Mass Fatality Identification System (M-FISys) for disaster recovery efforts and as a missing persons database.

But the Britons weren’t banking on needing it so soon.

London bombing 
Missing posters line the walls 
at Kings Cross for victims of
London's terrorist bombing.
Photo by  ZUMA Press
 
In the wake of the worst terrorist strike in British history in London last week, Chris Maguire, a senior scientist at Forensic Science Services (FSS) in London, placed a call to Gene Codes CEO Howard Cash at 5:30 a.m. on July 7. On July 12, Cash and one of his colleagues flew to London to set up the database.

Gene Codes, based in Ann Arbor, Mich., developed the M-FISys database after 9/11 to identify victims of the World Trade Center attacks through DNA analysis (see Soul Searching, Bio-IT World, September 2003). M-FISys was also used in the tsunami disaster of South Asia (see Tsunami Investigators Tap Gene Codes Database, Bio-IT World, April 2005).

Still, none of this is second nature to the Gene Codes team. Each disaster is accompanied by unique circumstances and complications, some of which call for last-minute upgrades.

“One of the things we’re working on right now are location markers,” said Cash, who spoke to Bio-IT World just hours before flying to London. “With the four sites in England, you don’t expect the remains of someone found at King’s Cross to also match with someone who was in the bus that exploded. We need meta data for what should and should not logically go together.”

File formats have also had to be changed since British formats differ from those in the U.S. “We had to make those changes very quickly,” Cash said.

FSS, which serves police forces in England and Wales, will be using M-FISys to match DNA samples provided by victims’ family members with remains found at the four disaster sites. So far, ten of the more than 50 bombing victims have been identified by traditional means. DNA analysis will only be needed to identify victims closest to the blasts.

“Forensic Science Services is one of the most respected forensic labs in the
world,” said Cash. “They don’t need our advice on how to collect samples or process materials. What we provide is bioinformatics and data handling.”

Unlike the tsunami and 9/11 disasters, the London bombings were confined to four relatively confined areas, which aids the recovery efforts. “This should not be a terribly long identification process,” Cash said. “The remains are not badly compromised like they were in the World Trade Center. These are not huge numbers or a wide geographical dispersion as with the tsunami.”

However, all of the recovered bodies and body parts in London must be X-rayed to determine whether debris or pieces of other bodies have been embedded into specimens by the force of the blasts. “Because it was an explosive device, more investigating has to be done on the site,” Cash said. “Bodies and pieces of bodies have to be X-rayed. That slows things down.”

Also slowing the effort are the conditions in the deep tunnels of the London Underground (subway) system. Temperatures have reached a stifling 140 degrees F, and progress has also been hampered by the need for isolation suits (to counter asbestos contamination) as well as myriad rats that have scampered onto the scene.

British authorities currently suspect that the terrorists traveled to London from West Yorkshire, and some, maybe all, of the suspects died in the blasts. If the remains of the terrorists are identified, they will promptly be escorted away from those of the victims.

“That’s been the tradition in the past,” Cash said. “I’m sure that will be the same in London. I think that’s just compassion on behalf of the families.”

Click here to login and leave a comment.  

0 Comments

Add Comment

Text Only 2000 character limit

Page 1 of 1

White Papers & Special Reports

isilon white paper

“Storage for Science – Methods for Managing Large and Rapidly Growing Data Stores in Life Science Research Environments” sponsored by Isilon
Large and rapidly growing stores of file-based and other data are a hallmark of life science research and bioinformatics. Determining how best to manage those data stores has become a significant challenge for Researchers and IT Pros alike.

This paper is intended to:

  • Provide guidance on the many storage requirements common to Life Science research;
  • Explain the evolution of modern storage architectures;
  • Summarize the major data storage architectures currently in use.

Additionally, it will present the Isilon IQ clustered storage product as a strong and flexible solution to those needs. Download now



definiens briefingon-76Next-Generation Technologies Revolutionizing Oncology and Diagnostics
underwritten by Definiens

This “Briefing On” collection of Bio-IT World features, commentaries and analysis, presents some of the latest thinking on high-throughput technologies that are being applied to the fields of research and drug discovery, with particular emphasis on oncology, diagnostics and imaging technologies. Download now at no charge compliments of the underwriting sponsor, Definiens. Download This Free Paper



metaminer image(1)

MetaMiner™ Cystic Fibrosis Report,  Sponsored by GeneGo
This paper discusses the MetaMiner™ (CF) data analysis platform for a broad range of CF researchers designed to: 1. Easily assemble important biological and chemical experimental data available today in cystic fibrosis research. 2. Visualize key mechanisms leading to the disease through pathway maps and network models 3. Provide the CF community a “one stop shop” tool for uploading and analyzing experimental data in a disease-centered interface.  Download now 



Life Science Webcasts & Podcasts

Storage for Science
Methods for Managing Large and Rapidly Growing Data Stores in Life Science Research Environments

Sponsored by Isilon

Isilon webcast1

Large and rapidly growing stores of file-based and other data are a hallmark of life science research and bioinformatics environments. Determining how best to manage those data stores has become a significant challenge for the Researchers and IT Professionals that support them.

This webcast is intended to: 

  • Provide guidance on the many storage requirements common to Life Science research; 
  • Explain the evolution of modern data storage architectures; 
  • Summarize the major data storage architectures currently in use;
  • Present the Isilon IQ clustered storage product as a strong and flexible solution to those needs.

    Download this webcast

More Podcasts

Job Openings

Isilon Systems ~ Senior Marketing Communications Manager
Isilon Systems is the worldwide leader in clustered storage systems and software for digital content and unstructured data. We seek an experienced marketing communications professional/writer expert in creating and delivering effective and persuasive business communications. The ideal candidate can think at the strategic and conceptual level and act, simultaneously, as a highly-effective and productive individual contributor. The position is based in Seattle, WA. For additional information click here:
 

Lilly Singapore Center for Drug Discovery (LSCDD) - Associate Director of Informatics
Lead and mentor a strong team for the Bioinformatics group at the Integrative Computational Sciences (ICS) department at LSCDD towards the development of novel algorithms, data analysis methods and software tools for drug discovery. Work closely with the Software Engineering group at ICS, and collaborate with the Discovery IT organization in Europe and USA. For additional information, or to apply visit: LSCDD 

For reprints and/or copyright permission, please contact RMS, 1808 Colonial Village Lane, Lancaster, PA;

(717) 399-1900 ext. 125 or via email to bio-itworld@theygsgroup.com.