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News & Reports: Mar 24

March 24, 2010 | Philips and Definiens Announce Collaboration
Royal Philips Electronics and Definiens signed an MOU to jointly develop and market clinical decision support solutions for digital pathology. The intended initial project between Philips and Definiens will focus on immunohistology-based breast cancer diagnostics, which includes the detection of biomarkers HER2, Estrogen Receptor (ER), Progesterone Receptor (PR), Ki67 and p53. Philips and Definiens also plan to investigate solutions for other cancers such as prostate and colon cancer.

“The memorandum of understanding with Definiens underpins Philips’ objective of offering a full suite of image analysis tools that can be used in combination with mainstream histological staining techniques and procedures in pathology,” says Bob van Gemen, GM of Philips Digital Pathology. More information.

Illumina Debuts Enhanced Custom Chip
Illumina unveiled HumanOmniExpress+ Custom BeadChip, an enhancement to the recently announced OmniExpress BeadChip that allows for the addition of up to 200,000 custom variants for a total of >900k variants per sample. OmniExpress+ leverages the proven iSelect custom genotyping infrastructure to provide researchers with unlimited flexibility in adding custom content for disease or pathway-specific markers, rare variants from the 1,000 Genomes Project, or panels for fine-mapping onto the industry's most optimal set of SNPs. For more information.

febit Launches Whole Genome Sequencing Servics in Europe
febit now offers whole genome sequencing services in Europe for a broad range of species. febit has acquired two Applied Biosystems SOLiD high-throughput sequencing systems from Life Technologies Corporation, necessary for whole genome resequencing. One of the two systems will be used within R&D while the other is employed within febit’s Genomic Service Department. For more information.

GeneGo Releases ToxHunter
GeneGo released the first set of tools and content stemming from its industry-FDA MetaTox partnership program. The MetaTox partnership is developing a comprehensive systems toxicology suite designed for compound safety assessment in chemical and pharmaceutical R&D. ToxHunter will be made available as an add-on to existing licenses of GeneGo’s MetaCore and/or MetaDrug systems biology and systems pharmacology platforms.

ToxHunter includes detailed ontology of compound-induced pathological observations covering 7 target organs in the initial release, as well as a comprehensive, manually-curated knowledgebase of gene, protein, metabolite, and chemical associations to pathology terms that is searchable by pathology, toxicant, or gene, protein & metabolite biomarkers. ToxHunter also enables new experimental analysis and visualization tools such as an enrichment module for identifying specific gene-pathology associations, and a suite of new toxicity-focused pathway maps and QSAR models. For more information.

Ingenuity Adds New Distributor

Ingenuity Systems selected Biodiagnostics as its new distributor of IPA in Greece, Turkey and the Balkan countries. IPA is a software application to model, analyze, and understand the complex biological and chemical systems in life science research. For more information.

Accelrys Discovery Studio 2.5.5 Released
Accelrys released Discovery Studio 2.5.5 an advanced computational chemistry and biology software application. This release, powered by Accelrys Pipeline Pilot features new algorithmic developments in the protein modeling area, access to the latest version of the popular GOLD docking program (licensed by CCDC), and enhanced usability and performance to meet the demands and challenges of modern drug discovery projects.

New scientific protocols include a 3D QSAR method and a protocol for calculating residue electrostatic energy for predicting protein stability and thermostability. Additional enhancements include two new user interface Discovery Guides and 64-bit server compatibility that significantly improves the performance of processor-heavy calculations. For more information.

M.D. Anderson Chooses Biotracker
Ocimum Biosolutions reported its Biotracker LIMS solution was selected by the University of Texas M. D. Anderson Cancer Center as the standard for the automation of their Research Core Facilities. The first core facility to be automated shall be the Genomics Core Facility. For more information.

ChromoTek Offers New Imaging Tools
ChromoTek launched new bioimaging tools RFP-Trap and GFP-Booster, used to identify and pull down interaction partners of proteins tagged with RFP (red fluorescent protein) and restores or increases the GFP (green fluorescent protein) signal in super-resolution microscopy. More information

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