November 23, 2009
| Bio-IT World

Industry Trends
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Pharma/Biotech
In-licensing Trends,
2005 -- 2008

By Mark P. Mathieu
Biotechnology in-licensing activity with large pharmaceutical manufacturers witnessed a dramatic acceleration beginning in 2006.   Estimates revealed total up-front considerations paid to biotech companies accelerated 42% to $1.6bn in 2006, up from $1.1bn in 2005; increased 32% to $2.6bn in 2008.  Read More


Top Headlines


Cycle Computing's Tour de Cloud
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Bio-IT World | Despite the enormous appeal of cloud computing, making practical use of resources such as Amazon’s EC2 is not straightforward. One key issue is scheduling. Jason Stowe, the founder and CEO of Cycle Computing, says that his firm’s service, the CycleCloud, attempts to solve a very straightforward problem: “Amazon allows you to provision 1000 servers. Now what?... How do you make it so the submission you just did 5 minutes ago starts running sooner than the submission yesterday, because its higher priority?”

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Warm Wellcome for Cloud Computing
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Bio-IT World | With a sequencing output approaching 500 Gigabases/week and electricity consumption a whopping 3 MegaWatts, the Wellcome Trust Sanger Institute (WTSI) is a prime contender for cloud computing. Guy Coates, group leader of informatics systems at WTSI, heads a quasi internal consulting team that sits between the hardcore systems teams and the research scientists. Kevin Davies caught up with Coates at Bio-IT World Europe to discuss the institute’s early experiences with cloud computing.

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Stephan Ignites a Medical Revolution in Northern Virginia
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Washington Post | Even as Washington policymakers struggle to reform the country's health-care system, about 20 miles away in Fairfax County, Ignite Institute and Navigenics founder Dietrich Stephan is hatching a plot to revolutionize it.

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Knome Expands Sequence Service to Research Community
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Bio-IT World | Knome, the first company to offer complete personal genome sequencing to the consumer market, is expanding its offerings to biomedical researchers and clinical investigators with KnomeDISCOVERY, the first “platform agnostic human genome sequencing and analysis service for researchers."

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The ‘C’ Word
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Bio-IT World | By his own admission, BioTeam co-founder and technology director Chris Dagdigian is a cynical sort, dedicated to the productive use of IT resources, focused on results and cost—and pathologically averse to marketing spin. That makes his positive reception to cloud computing all the more compelling. Just don’t call it “cloud computing.”

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Microsoft’s HPC Hopes at Supercomputing 2009
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Bio-IT World | Microsoft is making news at the Supercomputing 2009 (SC 09) conference in Portland, Oregon, by announcing the availability of beta versions of Windows HPC Server 2008 R2 and distributed Microsoft Office Excel 2010 for the cluster.

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White Papers & Special Reports

Adobe Beyond EDC whitepaper
Beyond EDC…Optimizing ROI by Streamlining Clinical Research Processes
Sponsored by Adobe

Although EDC brings tremendous efficiencies to clinical data collection, numerous repetitive clinical development activities exist beyond its scope which are in need of more efficient processes.  As these activities move from paper-based to electronic, the transition can be eased through the use of intelligent PDF forms.  Using XML capabilities, intelligent forms can follow workflows while leveraging established point solutions such as EDC, CTMS and IV/IWRS to optimize return on investment.
This White Paper describes:

  • How intelligent PDF forms can accelerate repetitive clinical development processes, leading to faster development timelines
  • How return on investment is maximized by being able to repeat time and cost savings across nearly all development phases and therapeutic areas
SURETY-IP_WPx108
“Protect Your Scientific Intellectual Property: Proof of Lab Informatics Data Authenticity is Your Best Legal Defense
Sponsored by Surety, LLC

“As a bio-technology or life sciences organization, your formulas, treatments and research and discoveries are the “lifeblood” of your business. But if you aren't protecting the integrity of your scientific data in your lab informatics systems, you risk losing IP ownership, revenue and consequently your business if you can't prove time-of-creation and data authenticity. Learn how you can implement simple, cost-effective and automated controls to protect your scientific intellectual property. Consider:

  • IP protection requirements in bio-pharma and other science-oriented industries can extend out 20, 30, 40 or more years
  • Most electronic lab management solutions include generic authenticity controls, so how "legally defensible" is yours?
  • Only standards-compliant, independent controls can future-proof your approach to long-term IP integrity protection and authenticity.
  • Learn more - get the free whitepaper now
BlueArc_WP_DataMigration.jpg
The Key to Life Sciences Data Management: Transparent Migration
Sponsored by BlueArc

Life sciences organizations face new data management challenges as the volume of research data grows and more data is kept online for longer times. Read this paper to learn about:

  • The benefits of transparent data migration (TDM)
  • How TDM technologies can simplify data management.
  • How using TDM can help increase storage utilization, improve computational workflow performance, and optimize the use of storage resources.


Expert Comment

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Performing in the Downturn and Beyond

By Jean-Marc Neimetz
Capgemini Consulting

November 10, 2009 | The life sciences industry is in a catch-22 situation accentuated by the current economic crisis, according to the eighth edition of Capgemini Consulting’s Vision & Reality report, Life Sciences: Performing in the Downturn and Beyond. Comprised of in-depth interviews with industry executives representing pharmaceutical, biotech, medical device, and agrichemical companies in Europe and North America, the report presents a perspective on cost initiatives affecting all life science industry players.

Innovation costs are escalating. Outcome-based trials and regulatory requirements are more complex, raising costs for new product approval and release. Meanwhile, price pressures, the combination of generics and shortened market exclusivity limit pharmaceuticals’ ability to fund innovation. Read more.

Bio-IT World invites contributed Expert Commentaries. Contact Kevin Davies with proposals.

Life Science Webcasts & Podcasts

tripos_logoIntroducing SYBYL-X: Changing CADD and Improving Workflows
Sponsored by Tripos 

SYBYL has historically been the single most used computer-aided drug design platform; however, as CADD has evolved from pure research into a more practical discipline, SYBYL has evolved into SYBYL-X. It now has the ability to make routine tasks fast and easy while enhancing key discovery workflows from obtaining data to delivering findings.  In this podcast, learn about:

  • How CADD has been changing
  • The breadth of science that is opened up in SYBYL-X 
  • Key elements of strategy for making CADD more efficient and productive

Download now 



Pantheon: Software for Optimized Chemical and Biological Data Merging
Sponsored by Tripos 

This podcast introduces Pantheon, new software enabling discovery scientists to rapidly merge chemical and biological data together and communicate results with their project teams.  Listeners will get answers to these questions:

  • How can I save time currently spent manually manipulating Excel spreadsheets and other sources of chemical and biological data?
  • How can I get the full view of my data with 2D and 3D views of my chemical structures?
  • How can I analyze a series of lead structures against multiple success criteria and select those with the best chances of success?

Download now 




Related Web Sites

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 eCliniqua

Innovative management in clinical trials

 Barnett Educational Services

Leaders in quality training resources

 Insight Pharma Reports

Reports evaluating issues in pharmaceutical technology, business, and therapeutic markets


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