The “Net Innovation Trend” and What It Means for Big Pharmas, Biotechs, and Generics
By Mark P. Mathieu
Innovation is the key value driver in healthcare. Over the past 8 years, the pharmaceuticals sector has lost a stunning $593 billion (-65%) in market cap while the two sectors with innovation – biotech and med tech – have each added $71 billion (+46%) and $19 billion (+6%) in market cap, respectively. Read More
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Isilon Rolls Out Unified Scale-Out Storage Platform
Sep 01
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Bio-IT World | Data storage company Isilon is introducing what it claims is the industry’s first and only unified scale-out storage platform for the enterprise, by integrating the iSCSI protocol into its OneFS operating system.
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Sanofi Calls Genzyme to the Table
Aug 30
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Forbes | Yesterday Sanofi-Aventis sent a formal "bear hug" letter to Genzyme shareholders hoping to start real negotiations. The letter didn't raise the offer of $69/share, but instead called Genzyme to the negotiation table or Sanofi would "consider all alternatives".
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Genetic Red Flag for ALS
Aug 27
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HHMI | Researchers at Howard Hughes Medical Institute (HHMI) have found a genetic risk factor for amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease).
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Introducing the Next Next Gen
Aug 26
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Australian Life Scientist | The third generation of sequence technology does away with cloning and PCR, and instead relies of fluorescense, single molecule sequencing, or silicon chips. Fueled by semi-conductor technology and electrical current, it will likely be Ion Torrent or Oxford Nanopore that reaches the goal of the $1000 genome first.
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Share the Data: Making Large-Scale Proteomics Data Widely Available
Aug 25
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Bio-IT World | Expert Commentary | Advancements in science and health care are made possible through widespread access to cutting-edge research data, as was clearly demonstrated during the Human Genome Project, where researchers collaborated to create an extensive data resource for the entire community. The proteomics community is beginning to implement analogous policies and infrastructure.
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Hugh Rienhoff Cops a Candidate Gene in His Daughter’s DNA
Aug 24
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Bio-IT World EXCLUSIVE | Hugh Rienhoff’s relentless search for the genetic basis for his daughter’s mysterious congenital syndrome has finally unearthed a legitimate but still unproven candidate for the disorder -- a homozygous frameshift mutation in the gene for copine-1.
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 | Remote Data Capture:Acquisition and Analysis See why Electronic Data Capture (EDC) is gaining traction in the pharmaceutical
clinical trials arena. Today approximately half of all clinical trials are conducted
electronically, and the figure is rapidly rising. Report includes contributions from
Oracle Health Sciences, Pfizer, PPD, and C3i. |  | The Role of Analytics in Transforming Healthcare Sharing many of the data challenges and opportunities faced by Healthcare, the Life Sciences industry remains focused on delivering new, innovative therapies and solutions to patients in a cost effective, timely and safe way. With spiraling R&D costs, new methods such as adaptive trials, and never ending need for deep pharmacovigilance, the Life Sciences companies that effectively use analytics to explore, monitor and optimize their business will rapidly become the new leaders. Oracle’s strategy—built upon Enterprise Health Analytics and Health Data Warehouse Foundation—provides a powerful, practical, and extensible approach to delivering the IT analytics infrastructure required to confront the worldwide healthcare challenge. |  | BPM-Based Case Management Approach to Optimizing Clinical Trial Efficiency Business Process Management (BPM) software offers liberation in the planning and management of clinical trials today. SmartBPM provides the components for automating critical clinical trial processes ranging from protocol development and patient enrollment to site management and investigator payments. Advantages are: - Potentially stunning return on investment at multiple levels.
- A 500%, or better, increase in application development time by directly executing business requirements
- Improved customer retention
- A 50% possible reduction in training time
Discovered is opportunity to enhance relationships with investigators, subjects, and regulators while bringing momentum to a technology-impaired study startup phase. Learn more about SmartBPM in this complimentary white paper. |
Bio-IT World & CHI
Impact of the 1000 Genomes Project on the Next Wave of Pharmacogenomic Discovery
 Interview with M. Eileen Dolan, Ph.D., Professor, Medicine, University of Chicago and Speaker at Next-Generation Sequencing Data Management, September 27-29, 2010, Providence, RI
The 1000 Genomes Project aims to provide detailed genetic variation data on >1000 genomes from worldwide populations using the next-generation sequencing technologies. Some of the samples utilized for the 1000 Genomes Project are the International Hap-Map samples that are composed of lymphoblastoid cell lines (LCLs) derived from individuals of different world populations. The detailed map of human genetic variation promised by the 1000 Genomes project will allow a more in-depth analysis of the contribution of genetic variation to drug response. Future studies utilizing this new resource can greatly enhance our understanding of the genetic basis of drug response and other complex traits.
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Aug 27, 2010
| Bio-IT World |
FULL STORIES
- ChemAxon licenses platform, toolkits to Broad Institute
- InnoCentive issues $20,000 Challenge targeting glucosepane
- Luminex donates MAGPIX instrument to Papua New Guinea Institute of Medical Research
- Ambry Genetics picks up an Illumina HiSeq 2000
Bio-IT Weekly Update
eCliniqua
Software Engineer – Computational Biology Center
Memorial Sloan-Kettering Cancer Center seeks an Engineer to design and develop complex data analysis systems in support of cancer genomics research projects at the Computational Biology Center. Qualified candidate will have a BA, 5+ years of software development experience and expert knowledge of Java, SQL, and HTML.
Apply: www.mskcciscareers.org. Equal opportunity and affirmative action employer.
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