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Grappling with Genomic Sequencing of Newborns

| MIT Technology Review | The BabySeq project in Boston has begun collecting data to quantify the risks and benefits of DNA sequencing at birth.

June News and Product Briefs

| Bio-IT World | News and product briefs from around the industry, including landmarks on the second anniversary of the Global Alliance for Genomics and Health, and the commercial launch of 10X Genomics' GemCode platform.

Clone-Free, Single-Molecule Genome Assembly Illuminates Structural Variation

| Bio-IT World | A large collaboration led by scientists at the Icahn Institute has combined PacBio sequencing and BioNano optical maps to produce the most contiguous human genome ever assembled without cloning steps, bringing a new degree of resolution to studies of complex structural variants.

Celgene To Pay $1B For A Big Piece of Juno and T Cell Therapies

| Xconomy | It seemed only a matter of time. One of biotech's most aggressive deal makers, Celgene has struck a wide-ranging, billion-dollar partnership with Juno Therapeutics.

#TCGC15: Databases, Genomics, and Making Clinical Sequencing Work

| Bio-IT World News Brief | The fourth annual Clinical Genome Conference wrapped up last week in San Francisco. It was a packed three days of short courses, presentations, and discussion that spilled over the time slots and into the evening. Thankfully, much of it ended up on Twitter.

Report from the Festival of Genomics

| Bio-IT World | A new event held this week in Boston, the Festival of Genomics, aimed to engage the public with this burgeoning science, while emphasizing to scientists the importance of data sharing and of integrating DNA data with meaningful health information in order to deliver on the promises of genomic medicine.

Mount Sinai Announces Precision Wellness Center

| Bio-IT World | The Icahn School of Medicine at Mount Sinai today announced the Harris Center for Precision Wellness. The center is part of the Icahn Institute for Genomics and Multiscale Biology and will be directed by Joel Dudley of the Icahn Institute and Gregory Stock, formerly of UCLA.

Google Genomics, Broad Partner, Offer GATK on Google Cloud Platform

| Bio-IT World News Brief | This morning Google Genomics announced a partnership with the Broad Institute of MIT and Harvard to, “combine the power, security, and scale of Google Cloud Platform with Broad Institute’s expertise in scientific analysis.” The first offering will be the GATK on Google Cloud Platform. 

Duplications in Figures, Data in Oncology Journals

| In the Pipeline | Here's a disturbing read for you: the author of this paper (Morten Oksvold, of Oslo University) sat down and did what none of us ever do. He chose three different journals in the oncology field, picked one hundred and twenty papers, at random, from their recent issues, and carefully looked every one of them over for duplications in the figures and data. On PubPeer, you can see what he found. Nearly a quarter of the papers had problems.

A Colorful Business

| Diagnostics World | Color Genomics is just one of several companies toying with a new model for selling low-priced DNA tests online, by enlisting physicians as intermediaries. If Color's business model becomes popular, it will have big implications for the way genomic testing reaches the broader public — and who sets the standards for this maturing technology.

Why Hasn't Big Data Come to Rescue Clinical Data?

| Clinical Informatics News | The cost-to-value equation for standardizing clinical data is broken. Pharmaceutical companies spend millions of dollars annually, and substantially delay products’ time to market, sending clinical data to contractors for preparation and integration before analysis. Why is the standardization process for clinical data still manual?

Googles data centers grow so fast it has to build its own networks

| Computerworld | Google has been building its own software-defined data-center networks for 10 years because traditional gear can't handle the scale of its warehouse-sized computers.

Juno's T-Cell Immunotherapy Cure for Cancer

| MIT Technology Review | Supercharge your immune cells to defeat cancer? Juno Therapeutics believes its treatments can do exactly that.

With Johnson and Johnson, Harvard Spinoff Emulate Unveils New Organs-on-Chips

| Bio-IT World | Emulate, a for-profit spinoff of Harvard's Wyss Institute, is announcing that a partnership with Johnson & Johnson has produced a new Thrombosis-on-Chip model for testing drug candidates and studying the biology of blood clotting, in a preview of the company's model for creating and disseminating next-generation organs-on-chips.

Tute Genomics Announces Investment Round from Intermountain, Tencent

| Bio-IT World News Brief | Tute Genomics today announced the closing of its Series A1 round of venture capital funding. The company raised over $3.9 million from a strategic group of investors, including Intermountain Healthcare, Healthbox, and China-based Tencent.

Matthew Trunnell Joins Fred Hutchinson Cancer Research Center

| Xconomy | Trunnell leaves the Broad to serve as the chief information officer as the biomedical institution moves into an era of deep genomic sequencing.

FDA taps PatientsLikeMe to test the waters of social media adverse event reporting

| mobihealthnews | PatientsLikeMe has announced a research partnership with the FDA: The agency will assess the platform's feasibility as a way to generate adverse event reports, which the FDA uses to regulate drugs after their release into the market.

Whole Genome Assembly with Nanopore Data

| Bio-IT World News Brief Nature Methods has published a paper by researchers at the University of Birmingham and University of Toronto, demonstrating a complete de novo assembly of an E. coli genome using only data from an Oxford Nanopore MinION Sequencer.

Outpouring of Commentary on CRISPR Germline Editing

| Bio-IT World News Brief | A supplementary document to a recent Nature Biotechnology article on the use of CRISPR-Cas9 genome editing in the human germline offers complete Q&A's with over 20 experts in the field, taking on pressing questions about how and whether this technology can be regulated.

ClinGen and Lessons for the Precision Medicine Initiative

| Bio-IT World | Heidi Rehm has been involved in ClinGen since its inception and recently published a report on the project in the New England Journal of Medicine. Rehm’s experience with ClinGen will make hers an important voice as the infrastructure needs for a Precision Medicine Initiative are better defined.
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