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Pharsight and Tripos Evolve, Prep PKS Online Launch: Aug 6

Predictive Biomedicine -- Informatics tools and strategies driving decisions 

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Pharsight and Tripos Evolve, Prep PKS Online Launch

ASTER Study Jumpstarts Adverse Event Reporting

Celera Pushes Boundaries with Automated Workflows

Short News & Analysis


Pharsight and Tripos Evolve, Prep PKS Online Launch
By John Russell

Later this summer, modeling s/w and services pioneer Pharsight will launch PKS online, a hosted version of its enterprise database and collaboration platform. It is one of the early steps in a planned journey to build a "translational science company" around the nucleus of Pharsight and Tripos which were acquired by Vector Capital and placed under a new umbrella brand, Certara.

The move to increase software as a service (SaaS) offerings is part of Certara's long-range strategy, says Dan Weiner, a Pharsight veteran who now serves as CTO for both companies, and it follows successful efforts by tool makers such as Phase Forward and SAS to do the same. PKS online is aimed largely at smaller pharmas and biotechs with tight budgets and fewer internal IT resources, but the company says cash-squeezed larger companies may also find the offering attractive. More.


ASTER Study Jumpstarts Adverse Event Reporting
By Ann Neuer

Michael Ibara, head of pharmacovigilance information management at Pfizer, has a real passion for improving patient safety. At the recent DIA meeting, he chaired a session on a highly original pilot study focused on a simple way for busy clinicians to report adverse drug events (ADEs) to MedWatch, the FDA's safety information reporting program. The study, named ASTER--ADE Spontaneous Triggered Event Reporting--is wrapping up its three-month pilot, which was conducted earlier this year at two Partners HealthCare hospitals in Boston--Brigham and Women's and Massachusetts General Hospital (MGH). More.


Top Story Last Issue
Celera Pushes Boundaries with Automated Workflows
By John Russell

The use of leading edge informatics tools is part of Celera's DNA. In the race to sequence the human genome, high performance computing and sophisticated home-grown informatics were as important as high speed sequencing machines to Celera's success. Celera is hardly that company today, having redefined its mission to become a leader in diagnostics and "personalized disease management." What hasn't changed is its use of leading edge informatics. More.


Short News & Analysis

(Click for Full Briefs)

GeneGo Gets NIH Grant to Develop PGx Software
The SBIR grant is for a database and systems biology tool-set specifically designed to..

Hutch leader Hartwell Will Retire next June
Nobel Laureate Lee Hartwell will retire next year as director of the Fred Hutchinson Cancer Research Center..

Celera Restructures; Will Cut Workforce 13%
Celera announced an immediate restructuring program, which includes the elimination of approximately 80..

IO Informatics Unveils Applied Semantic Knowledgebase
ASK allows you to move beyond traditional data capture and integration to realize..

Genedata Launches Expressionist Migration Program
The new bundle includes the Genedata Expressionist system and a targeted set of professional services..
Definiens Completes ISO 9001
Definiens completed the certification process for DIN EN ISO 9001:2008 and EN ISO 13485:2007..

DNA Software Gets 3 Fast Track SBIR Grants
The NIH grant are to develop original in silico technologies to predict 3D structures of RNA-based molecules..

Genego Donates Cytokine Pathway Maps to ISICR
41 maps were donated to the International Society for Interferon and Cytokine Research ( The donated maps describe the role of interferons..
Microsoft Issues Presentation Call for BioIT Alliance Meeting
The first annual 2009 BioIT Alliance Meeting and Conference will be held October 8 and 9, in Cambridge, MA..

Biovista Reports Positive Results for BVA-601 for Epilepsy
BVA-601 has shown positive results in the Kainic acid murine model of temporal lobe epilepsy..

Agilent Technologies to Acquire Varian for $1.5 Billion
The acquisition broadens Agilent's applications and solutions offerings in Life Sciences..

Mid Summer Reading, Listening, and (Web) Site-seeing
Harvard Medical School professor Walter discusses Web 2.0 tools for systems biology..

Predictive Modeling for Healthcare Summit
The Third National Predictive Modeling Summit will in Washington DC..

(Click for Full Briefs



Accelrys Inc.
Product Manager, Enterprise Technologies
San Diego, CA
Job Code: PMET
The Product Manager of Enterprise Technologies will be responsible for the strategy and roadmap of our world-class Pipeline Pilot informatics platform. Undergraduate degree in science, informatics, or engineering required. Minimum of 6 years of experience required with enterprise informatics software as a Product Manager. More information found at 

Accelrys, Inc.
Product Manager, Biological Sciences
San Diego, CA
Job Code: PMBS
This critical position will manage the complete lifecycle of the Biological Registration suite of databases and applications. Experience in biological databases, biological data management, sequencing, text mining and analytics, or electronic lab notebooks required.  Minimum of 6 years of experience within scientific software or related industries. More information found at

To have your job openings featured here, contact Lynn Cloonan for more information.



How to Improve on New Drug Treatment Education

HPC Virtual Event 

Data Storage Problems? Get fast answers here

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Biomarkers accelerating drug development

Scientific Data Lifecycle Management-Free paper!

Electronic Notebook: Streamline experimental IP; capture and re-use data; enhance collaboration.

Learn how you can Accelerate Data Management Application Development 10x 

Shorten Your Work Day Through Secure Web Conferencing-Free Webinar 

Novoseek, the biomedical search engine based in text mining technology.

Next-Generation Sequencing: Solving the Genome 

To have your product or service featured here, contact Lynn Cloonan  for more information.


Insight Pharma Reports

Bioinformatics and Computational Biology: Bottlenecks and Options
Author:  K. John Morrow, Jr., Ph.D.

Bioinformatics and Computational Biology: Bottlenecks and OptionsThe interdisciplinary fields of Bioinformatics and Computational Biology are locked in a high stakes race with analytical instrument developers and innovators. The pace and scope of change in many fields of biomedical research rivals what we once associated only with semiconductor devices.  Bioinformatics and Computational Biology: Bottlenecks and Options presents an analysis of the state of the field in terms of the current systems biology models and their applications, where the field is headed and the possible implications for applied biological science.  Read more.



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Biomarkers: An Indispensible Addition to the Drug Development Toolkit
Examining the Potential of Biomarkers.  This white paper provides insight from experts in industry and academia, and explores the role of biomarkers as evaluative tools in improving clinical research and the challenges this presents.
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Scientific Data Lifecycle Management: Preparing for Storage in an Uncertain Future
Help your organization maintain control over vast and overwhelming streams of data and prepare for the future of sequencing through this informative paper. Download the paper    (sponsored by BlueArc)

Managed Innovation, Assured Compliance
Developing, executing and managing the transformation, analysis and submission of clinical research data with SAS® Drug Development.
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What’s Wrong with Biomarkers?
No one doubts biomarkers’ long-term value, but many obstacles remain. Read this in-depth analysis in which distinguished experts examine biomarker challenges, failures, barriers, and need for standards. 
Download the Briefing   (sponsored by Definiens)

Protecting Intellectual Property 
In this white paper we explore the issues facing patent creation and defence in the electronic age and discuss the tools and functionality required to protect innovation.  Access the Paper (sponsored by IDBS)

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At the Bio-IT World Conference & Expo, Chris Dagdigian talked about the old news, breaking news, and future of bio-IT. Get his perspective on what's overhyped and what's worth the buzz. View the webcast. 

The Future of Personal Genomics
An expert panel candidly discussed the future of personal genomics and what that means for both companies and consumers at the Bio-IT World Expo. Clifford Reid (Complete Genomics), Philip Reilly (3rd Rock Ventures), Dietrich Stephan (Navigenics), Robert Green (Boston University), John Halamka (Harvard Medical School), and Jorge Conde (Knome), give their unique perspectives on how this emerging industry could change medicine. View the webcast.

Boguski's Resounding Health
Mark Boguski is launching a new direct-to-consumer Internet search firm called Resounding Health and he tells Bio-IT World Editor, Kevin Davies, all about it. His goal is to create value-adding process networks to provide the most cost-effective management of chronic diseases in the near future. View the webcast.

Open Source Models for Personalized Medicine
Through the company he founded, CollabRx, Jay Tenenbaum aims to leverage the extraordinary untapped expertise and resources across the industry to empower individual patient health care through personalized research. View the webcast.


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Cambridge Healthtech InstitutePublished by Cambridge Healthtech Media Group, division of CHI, Copyright © 2009; All rights reserved. Predictive Biomedicine may not be reproduced, electronically or in print, by any means, mechanical or electronic, in whole or in part, without written permission of Cambridge Healthtech Media Group, 250 First Ave., Suite 300, Needham, MA, 02494. 
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