• GA4GH Phenopackets Standard Published By ISO

    Bio-IT World | The International Organization for Standardization (ISO) has published Phenopackets, a standard initially developed by the Global Alliance for Genomics and Health and championed at ISO under the Canadian Mirror Committee to ISO/TC215/SC1 Genomics informatics, and supported by the Standards Council of Canada.

    Aug 10, 2022

  • Online ‘Biclustering’ Tool Stratifies Patients To The Molecular Level

    Bio-IT World | Researchers in Germany have developed a web-based tool, powered by machine learning, which extracts disease subtypes from large pools of patient data. The goal is more precise and robust predictions about molecular signatures that can serve as a starting point for investigating disease heterogeneity.

    Aug 9, 2022

  • How Deleted and Siloed Data Are Slowing Discovery

    Bio-IT World | Though advancements in instruments and software have driven life sciences breakthroughs that drastically improve global health outcomes, researchers still struggle to maximize the value of the huge datasets that these high-throughput technologies generate. Currently, two common practices stand in the way of good data management at many life sciences institutions.

    Aug 5, 2022

  • Bio-IT World Announces European Best of Show Awards

    Bio-IT World | Bio-IT World is bringing the Best of Show competition to Europe this fall at the Bio-IT World Conference & Expo Europe in Berlin, October 18-19.

    Aug 3, 2022

  • Electrical Tissue Dissociation Outperforms Mechanical, Chemical Approaches

    Bio-IT World | A team of researchers from Brown University are in the process of developing a simple, inexpensive, portable device to electrically dissociate tissues into viable single cells. They’ve published the work in Scientific Reports, and foresee the approach being useful in both clinical diagnostics and basic scientific research.

    Aug 2, 2022

  • Target Discovery Engine for ALS, DRAGEN Update, Anti-Aging Analytic Software, More

    Bio-IT World | Merck announces a Digital Sciences Studio to support early-stage biomedical startups; a new suite of informatics tools anticipates pharmaceutical manufacturing bottlenecks; Novartis Pharmaceuticals UK announces the Novartis Biome UK Heart Health Catalyst 2022 Initiative; and more.

    Jul 28, 2022

  • Follow the Money: Lipid Nanoparticle Delivery Platform, Regulatory RNA Targeting, More

    Bio-IT World | Funding for Pylera commercial rights, in vivo biologics design platform, precision cancer therapy, and more.

    Jul 27, 2022

  • The Gift of the Outlier: George Church on Neurodiversity, Collision of Bad Ideas, and Thinking Visually

    Bio-IT World | In the latest episode of Bio-IT World’s Trends from the Trenches podcast, host Stan Gloss, founder of BioTeam, talks with George Church about how neurodiversity has shaped his education and scientific career and how a trait they share—dyslexia—leads to some out-of-the-box thinking.

    Jul 26, 2022

  • Inaugural Illumina Genomics Forum Hosts Former U.S. President Barack Obama

    Bio-IT World | Illumina announced the inaugural Illumina Genomics Forum, a global event championing the positive impact of genomic health. From September 28 through October 1, genomics, healthcare, and health policy innovators will convene to discuss how genomic tech fosters better predictive care, diagnoses, and therapeutics.

    Jul 21, 2022

  • TetraScience Announces GxP Solution, $500M Investment in Scientific Data Cloud

    Bio-IT World | Today, TetraScience announces the expansion of the Tetra Scientific Data Cloud to include manufacturing and quality control (QC) data and pledges $500 million over the next five years to further development.

    Jul 20, 2022

  • AI-Powered Microbial Mapping Paves the Way for Designer Gut Microbiomes

    Bio-IT World | A team of biologists and engineers from the Universities of Michigan and Wisconsin used a synthetic human gut microbiome to study the interactions between intestinal microbial communities. Their findings lay the groundwork for designer microbiomes with target functions.

    Jul 19, 2022

  • Automating the Genomic Medicines of the Future

    Bio-IT World | Historically, the heavily regulated biopharma industry has been slow to adopt new technologies. However, a shift toward automation is vital to ensure that next-generation solutions produce at scale.

    Jul 15, 2022

  • Oak Ridge Researchers ID Proteins that Can Block Tumor Growth Pathway

    Bio-IT World | Researchers at the Department of Energy’s Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins to the activation—and deactivation—of the c-MET pathway, which leads to the progression of tumor growth and metastatic cancer cells. Mutating any of four proteins blocks pathway progression.

    Jul 14, 2022

  • St. Jude Sickle Cell Research Team Warns Geneticists to Choose ‘the Right Mouse for the Job’

    Bio-IT World | Mitchell Weiss and fellow St. Jude team members devised autologous hematopoietic stem cell gene-editing techniques with hopes of curing sickle cell disease, but not without the “right mouse for the job.”

    Jul 12, 2022

  • For Drug Discovery Research, Laboratory Automation Needs to Be Flexible

    Bio-IT World | Scientists who want to implement automation in their laboratories should choose an infrastructure that can provide long-term flexibility for their teams. Increasing productivity with automation is essential to make that vision possible, and flexibility is critical for researchers to change workflows and take on new priorities quickly.

    Jul 8, 2022

  • Drug Repurposing Strategy Without An ‘Answer Book’

    Bio-IT World | Scientists working in the information biology lab at Hokkaido University in Japan have come up with a drug repurposing strategy combining machine learning, unsupervised clustering of gene expression, and two-stage prediction.

    Jul 7, 2022

  • Millimeter-Sized Feats Of Engineering Could Enable Smart Drug Delivery

    Bio-IT World | At Stanford University, precisely targeted drug delivery is in view using wireless micromachines that can navigate the rugged terrain of the human body, including the slippery surface of organs and vessels where blood flow may be impeded by hypertension and arterial plaques. The all-in-one amphibious robots’ locomotion is controlled by the strength and orientation of a three-dimensional magnetic field.

    Jul 5, 2022

  • Remote AI-Run Robotics Lab, Gut Microbiome as Targetable Biomarker, More

    Bio-IT World | A comprehensive ligand- and structure-based design platform delivers new and improved features for molecule design; an advanced automated GC headspace sampler and GC/mass spectrometry solution helps lab teams simplify operations; 10x Genomics releases a series of profiling products; and more.

    Jun 30, 2022

  • Follow the Money: Drug Discovery Robotics Lab, Clinical Sequencing Platform, More

    Bio-IT World | Funding for single-cell sequencing, small molecule drug discovery, neurological biomarkers, and more.

    Jun 29, 2022

  • Susan Gregurick Previews Potential Elements of NIH’s Next Strategic Plan for Data Science

    Bio-IT World | In the latest episode of Bio-IT World’s Trends from the Trenches podcast, Susan Gregurick, Associate Director for Data Science and Director of the Office of Data Science Strategy at the National Institutes of Health, gave a peek into what’s coming in the next iteration of the NIH Strategic Plan for Data Science.

    Jun 28, 2022