• New Discovery Data Architecture Needed to Support New Modalities

    Oct 22 | Bio-IT World | Increasingly, the discovery and development of new medicines is embracing bioactive modalities beyond traditional small molecules, both as therapeutic agents and delivery mechanisms. I propose that the industry create standards that describe not only how experimental and substance data should be treated but also cover the services that provide access to that data. More
  • UC Berkeley, UCSF Launch Computational Precision Health Program

    Oct 21 | Bio-IT World | Funded by an anonymous $50 million gift, the University of California, Berkeley and UC San Francisco yesterday announced a joint program in computational precision health. More
  • Janssen’s Data Ecosystem and the Role of Data Managers

    Oct 20 | Bio-IT World | At the Bio-IT World Conference & Expo last month, Aleksandar Stojmirovic and Weiwei Schultz, both of Janssen’s Data Science group, explained the data management mission and vision of Janssen R&D. More
  • Novel Peptide Drugs Offer Extended Pain Relief

    Oct 19 | Bio-IT World | University at Buffalo (UB) researchers plan to commercialize a platform for site-of-injury pain relief that targets nerve endings, the starting point of pain signaling, using lipidated peptides (peptides modified with lipid molecules) that prevent overexcitement of pain neurons. More
  • Herophilus Aims To ‘Industrialize’ Use Of Organoids For Drug Discovery

    Oct 14 | Bio-IT World | A San Francisco-based startup is using robotic automation to “industrialize” the organoid and scale up use of the next-generation human in vitro models in drug discovery experiments for brain diseases. The plan is to use these intact systems, inclusive of microglia as well as neurons, to go after genetically complicated diseases and apply machine learning techniques to find connections between the multi-phenotypic data that gets generated. More
  • Bio-IT World Issues 2022 Innovative Practices Awards Call for Entries

    Oct 13 | Bio-IT World | Bio-IT World is accepting entries for the 2022 Innovative Practices Awards competition. The deadline for entry is March 1, 2022, and the $300 application fee will be waived for entrants who meet the early deadline of January 14, 2022. More
  • Export Of Damaged Mitochondria To The Heart May Explain ‘Obesity Paradox’

    Oct 12 | Bio-IT World | Exosomal trafficking from fat to heart cells may help explain the “obesity paradox,” the baffling observation that packing extra pounds can have a beneficial, if short-term, protective effect for patients with heart disease. The cargo being delivered are oxidatively damaged mitochondrial particles that appear to prompt the heart to produce a flood of protective antioxidant molecules, better preparing it to cope with insults that later come along—such as a heart attack. More
  • Follow the Money: CRISPR, Next-Gen Neuroscience, Protein Platforms

    Oct 11 | Bio-IT World | CRISPR unicorn, pan-coronavirus vaccine research, chemical and biological weapons protection for warfighters, new methods for live cell research, seed round for a new drug discovery platform, and more. More
  • Amazon Genomics CLI is Open Source, UK Biobank’s Research Analysis Platform Live, More

    Oct 07 | Bio-IT World | New leadership at JAX, Illumina expands into Latin America, PacBio partners with The European Reference Genome Atlas, UK Biobank’s Research Analysis Platform is now live, and BC Platforms seeks to build the largest integrated clinical and genomics data biobank in Africa. Plus: new products from MemVerge, Quantum, Pure Storage, Sensyne Health, and more. More
  • Pistoia Alliance Gauges Life Sciences’ Quantum Computing Outlook

    Oct 06 | Bio-IT World | The Pistoia Alliance surveyed life sciences professionals this summer to gauge their understanding of quantum computing. They found that almost half classify their understanding of quantum computing (QC) technology at beginner level only. These results, the Alliance argues, show that despite significant noise around the potential of QC, few life science organizations or individuals are yet able to apply the technology. More
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