• Neighborhood Analysis Highlights Role Of Macrophages In ER+ Breast Cancers

    Mar 22 | Bio-IT World | When it comes to breast cancer, the most commonly occurring estrogen receptor-positive (ER+) variety is a poor candidate for treatment with conventional immunotherapies designed to help the patient’s own immune system fight back. Unlike triple-negative breast cancer, ER+ tumors don’t have many infiltrating T cells so potentiating their function alone doesn’t make much of a difference. More
  • Japanese Medical Team Discovers Gut Microbiota to Diagnose and Treat Dementia with Lewy Bodies

    Mar 21 | Bio-IT World | A research team from the Nagoya University Graduate School of Medicine, Japan, discovered three gut bacteria types that may lead to predicting and treating dementia with Lewy bodies. More
  • Current Microbiome Analyses Turning Up High Number Of False-Positives

    Mar 16 | Bio-IT World | Insufficient taxonomic information in public sequence records is a longstanding problem that was again brought to light in a recent study of simulated microbial communities. Researchers in Spain, using standard techniques to explore virtual microbiome communities, found that results obtained from DNA analyses bear little resemblance to the real-world bacterial populations being imitated and many of the detected species are not actually present. More
  • Marker Discovered Signaling Squamous Cell Skin Cancer About To Spread

    Mar 15 | Bio-IT World | Researchers have found that dyskerin, a protein that provides stability to non-coding small nucleolar RNAs, signals when cutaneous squamous cell carcinomas are preparing to metastasize by migrating to the lymph nodes. Because these cancer cells temporarily stop consuming glucose and instead feed on low-density lipoprotein cholesterol molecules, the new marker may be a promising candidate for treatments involving lipid metabolism inhibitors. More
  • Spatial Biology Poised for Explosion by 2027

    Mar 14 | Bio-IT World | Spatial biology is poised for an explosion in the next few years, said Colin Enderlein, a principle at DeciBio Consulting. Speaking in San Diego at the Molecular and Precision Med Tri-Con, Enderlein shared the results of DeciBio’s recent market report on the space. More
  • Craig Venter on Genomics’ Past and Precision Medicine’s Future

    Mar 09 | Bio-IT World | Kevin Davies and Craig Venter sat down together to celebrate thirty years of the Molecular and Precision Med Tri-Con this week in San Diego on Monday night. Davies—the founding editor of Bio-IT World—gave a guided tour of human genomic research and sequencing since 1991 with Venter offering first person color commentary along the way. More
  • New Telomere Measuring Method Addressing Limitations Of Current Options

    Mar 08 | Bio-IT World | A research collaboration led by led by Duke-NUS Medical School and National Heart Centre Singapore has set the stage for telomere measurement to one day be added to the list of clinical-grade methods for assessing biological aging. The focus is on rapid and precise measurement of individual telomeres using a technique that employs “telobaits” that latch onto the ends of telomeres in large pools of DNA fragments. More
  • Pharma-Diagnostics Lockstep: How Two Industries Can Work Together for Precision Medicine

    Mar 07 | Bio-IT World | Sarah Hersey, VP of Precision Medicine at Bristol Myers Squibb, gave a balanced view of the challenges and opportunities facing precision medicine in her keynote address at the Molecular & Precision Medicine Tri-Conference in San Diego this week. After her presentation she was joined by others in the space to talk about the future for diagnostics and precision medicine. More
  • Therapeutic Targets For MS Found In The Gut

    Mar 02 | Bio-IT World | Neuroscientists at the University of Virginia have succeeded in alleviating the harmful inflammation of multiple sclerosis in a mouse model of the disease by modulating the gut microbiome to disable a key immune regulator known as aryl hydrocarbon receptor. More
  • Forged in Steel, Exscientia Brings New Processes to Drug Development

    Feb 28 | Bio-IT World | Andrew Hopkins, CEO and Executive Director of Exscientia, speaks with host Stan Gloss of BioTeam about Exscientia’s machine learning-based and model-driven approach to drug design, the connection between knowledge and efficiency in drug optimization projects, and its fourth platform-designed drug launch into the clinic. More
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Trends from the Trenches

Bio-IT World’s Trends from the Trenches podcast delivers your insider’s look at the science, technology, and executive trends driving the life sciences through conversations with industry leaders. BioTeam co-founder Stan Gloss brings years of industry experience in science, data, and technology to conversations exploring what is driving data and discovery, and what’s coming next.
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