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More ‘Omics for SARS-CoV-2, Insights into the Spike Protein, Crowdsourcing Questions: COVID-19 Updates
TODAY | Bio-IT World | A Canadian team shares a new mechanism of action for remdesivir, data science groups have computed consensomes (gene expression in the virus) and interactomes (potential molecular mechanisms of pathogenesis) and cryoEM images the spike protein. Plus, NIH funding for new vaccines and the Reliable Response Data Discovery consortium takes COVID-19 patient data questions. more

Ecological Modeling Of Gut Microbiome Points To Probiotic Cures
| Bio-IT World Fecal microbiota transplantation (FMT), the idea of using fecal material from a healthy person to treat others who are sick, has been proposed for challenging conditions ranging from inflammatory bowel disease to autism and obesity. But to date, robust evidence from randomized clinical trials exists only for the use of FMT to treat recurrent C. difficile infection. more

The Role of Data Management in Advancing Biology
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Bio-IT World Kjiersten Fagnan had a plan: she would be an engineer, work for a company, and write software all day. But biology is intriguing and now Fagnan is the Chief Informatics Officer at the Joint Genome Institute. She recently spoke with Stan Gloss, founding partner at the BioTeam, about the community challenges around creating and sharing more useful data, and how “human engineering” can help advance biology.

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Sticky Webs, A Tiny Molecular Weapon, Obesity Paradox N/A: COVID-19 Updates
| Bio-IT World New drug targets, reconstructing viral spread and lineage, monitoring mutations, reasons to focus on T-cell responses, DNA webs as culprits of tissue damage, a very tiny neutralizing agent, explaining paradoxical risk in people with obesity and diabetes, and the value of heparan. Plus, a new vaccine candidate heading to human trials, coronaviruses are being profiled, and a deep dive on how SARS-CoV-2 weakens the immune system. more

Targeted Protein Degradation: Why Just Inhibit What Can Be Destroyed?
| Bio-IT World Disease treatment through targeted protein degradation takes a range of approaches: from small molecules similar to thalidomide that act as “molecular glue” degraders to more advanced “beyond rule of 5” proteolysis-targeting chimeras (PROTACs) with bifunctional moieties that encourage protein interaction with its E3 ubiquitin ligase. more

Continuous Software Validation Critical for Balancing Digital Transformation and Compliance
| Bio-IT World  The adoption of cloud technology in the life science industry has become increasingly pervasive as firms move forward with digital transformation initiatives aimed at creating operational efficiencies and delivering the next wave of biomedical innovations. As a result, cloud vendors are playing a more important role than ever before, especially for life sciences companies that produce FDA-regulated products. more

VAST Data Launches LightSpeed Storage Architecture
| Bio-IT World VAST Data has launched its next generation storage architecture, LightSpeed, which combines the light-touch of VAST’s simple NAS appliance experience with leadership-class performance for GPU-based and AI Processor-based computing, taking the guesswork and configuration out of scaling up AI infrastructure. more

Follow the Money: Alzheimer’s Meds, Single Cell Multi-Omics Technology
| Bio-IT World NIH contracts to explore radiation countermeasures, Alzheimer’s medication, and convalescent plasma, Mission Bio gets $70M for single cell multi-omics technology, and more. more

No Cytokine Storm, ‘Bursty’ Disease Spread: Biomarkers For Elevated Risk: COVID-19 Updates
| Bio-IT World  | Japanese researchers argue there is no cytokine storm, computer-designed protective proteins, ELISA test for antibodies, COVID-19’s impact on Black and Hispanic communities, a “burstier” model of disease spread, and new biomarkers for elevated risk. Plus, the International Vaccine Institute preps with Gates money, 3M funds vaccine researcher, and more. more



Jumpcode Genomics Exits Stealth Mode, Unveils Technology that Addresses the ‘Needle in the Haystack’ Problem of Molecular Biology
| CARLSBAD, CA, UNITED STATES - Sep 17, 2020 - Jumpcode Genomics – a genome technology company founded by industry veterans in 2016 focused on improving the understanding of human disease – today exited stealth mode and announced the commercial launch of its CRISPRclean™ technology more

Romain Madelaine, Ph.D., Joins MDI Biological Laboratory Faculty
| BAR HARBOR, ME, UNITED STATES - Sep 17, 2020 - The MDI Biological Laboratory has announced that Romain Madelaine, Ph.D., has been appointed to the faculty as an assistant professor more

Huntington Study Group Announces a Partnership with Prilenia Therapeutics to Conduct a Global Phase 3 Clinical Study of Pridopidine in Huntington’s Disease
| ROCHESTER, NY, UNITED STATES - Sep 17, 2020 - The Huntington Study Group (“HSG”), a world leader in clinical research for Huntington’s Disease (HD), announces a partnership with Prilenia Therapeutics, a clinical stage biotech company led by Michael R more

ZEISS enhances efficiency in multi-scale and multi-modal workflows
| JENA, GERMANY - Sep 2, 2020 - Materials and Life Science researchers can now experience faster accessibility of deeper regions of interest when investigating samples in 3D more

2bPrecise Wins Industry Innovation Award
| RALEIGH, NC, UNITED STATES - Sep 16, 2020 - Fierce Healthcare released its annual Fierce Innovation Report this week, naming 2bPrecise the industry’s top clinical information management solution more

Imvax Appoints Wendy DiCicco as New Board Member
| PHILADELPHIA, PA - Sep 16, 2020 - Imvax, Inc., an emerging oncology leader that is revolutionizing immunotherapy for patients with malignant glioblastomas (GBM) and other solid tumors with significant unmet medical needs, today announced the appointment of Wendy DiCicco to its board of directors more

Accumen Launches MyBloodHealth®, a Virtual Anemia Management Software Solution for the Perioperative Patient
| PHOENIX, AZ - Sep 15, 2020 - Accumen Inc. is helping healthcare get better, faster. Today the company launched its first software-as-a-service (SaaS) solution, MyBloodHealth®, a hospital-based telehealth anemia management program with both perioperative and comprehensive blood management options more

CANARIE Selects and Funds CanDIG Project to make Research Clinical Data FAIRer
| TORONTO, ON, CANADA - Sep 15, 2020 -  With advances in imaging technologies, new wearable health devices, mobile devices allowing patients to provide survey responses everywhere, and increasingly integrated electronic health records, health data consented for advancing biomedical research has never been more plentiful – or complex more

Adventist Health Enhances Online Access for Both New and Existing Patients with Kyruus and Cerner Collaboration
| BOSTON, MA, UNITED STATES - Sep 15, 2020 - Kyruus, the leader in provider search and scheduling solutions for health systems, and Cerner Corporation, a global healthcare technology company, today announced that Adventist Health, a faith-based, nonprofit integrated health system serving the West Coast and Hawaii, has enhanced its digital consumer access experience with integrated technology solutions from the two companies more



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