(June 26, 2018)

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Webinar Description:

A changing clinical trial landscape
The clinical trial landscape for precision medicine has shifted significantly in recent years towards multiple biomarkers being used to select patients for multiple therapies (umbrella studies) or include patients from multiple cancer types (basket studies).

When multiple biomarkers are required in these types of studies, this usually involves complex logistics with multiple vendors and excessive sample requirements which can increase time to manage and cost to run.

Diagnostic solutions for multi-arm clinical trial design
Almac Diagnostics has created novel panel solutions for complex clinical trials – enabling clients to evaluate multiple biomarkers from one sample, whilst saving precious tissue, time and cost. Almac offer a full portfolio of DNA and RNA assays which can be run using dual extraction from one FFPE sample. When combined, the assays provide a comprehensive review of tumour biology, the results of which are presented in an easily interpreted patient molecular data report which can be tailored to client requirements.

Learn about Almac’s:

  • Novel strategy for patient stratification in basket & umbrella trials
  • A solution to enable multiple biomarkers to be evaluated from one sample
  • DNA & RNA panel solutions for translational research & clinical trial use
  • Customised patient reporting enabling simple interpretation of molecular data


Steven WalkerDr Steven Walker
Head of Internal Product Management
Almac Diagnostics

Dr Steven Walker heads the internal product management activities at Almac Diagnostics. Specifically, this includes the development of internal discovery of biomarker assays towards commercialization as a diagnostic test delivered directly from Almac CLIA and CAP accredited laboratories, or as a companion diagnostic test for in partnership with Pharma / Biopharma.

Steven studied at the University of Dundee, leading to a PhD before postgraduate work at the Beatson Cancer Research UK Institute in Glasgow. He joined Almac Diagnostics in 2005, initially as a Senior Scientist, then as Team Leader and then Research Manager before taking the role in Product Development. As part of his time with the research team, he was involved in the discovery and development of several of the internally discovered biomarker assays.