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MicrobioSeq Introduces Microbial Iso-Seq to Characterize the Diverse Landscape of Transcript Isoforms

May 20, 2021

MicrobioSeq represents the microbial genomics division of CD Genomics headquartered in New York, USA. CD Genomics is a genomics service company with good reputation in providing reliable de novo sequencing, genotyping, microarray, and bioinformatics services. With years of experience in the pharmaceutical and life science sector, CD Genomics has recently announced microbial iso-seq to offer complete solutions for full-length transcript sequencing.

 

Microbial Isotype Sequencing (Iso-Seq) is an ideal method for analyzing microbial transcriptomes and gene fusion events and characterizing gene isotypes and alternative splicing events. CD Genomics's microbial iso-seq service can provide full-length reads without assembly, using PacBio single molecule and real-time (SMRT) technology to extend the entire transcription subtype from polyA-tail to the 5'end.

 

“Our fungal iso-seq or bacterial iso-seq can provide a complete solution for full-length transcript sequencing. It is a powerful technology that combines Illumina and PacBio SMRT sequencing platforms to identify high and low expressors in a single bacterial or microbial population. PacBio SMRT sequencing can sequence continuous full-length transcripts and capture the start, splice site, and polyadenylation of each transcript from a single read. Illumina's short reads will be further mapped to the PacBio SMRT full-length transcript for more accurate quantitative analysis and error correction.” said the Chief Scientist of CD Genomics.

 

What are the advantages of Microbial Iso-Seq service provided by CD Genomics?

 

  1. Efficient, standard workflow, fast turnaround time and comprehensive bioinformatics analysis in a cost-effective manner.
  2. Provide comprehensive data analysis by using widely accepted mainstream software and mature internal pipelines to discover novel transcripts, functional annotations and differential expressions.
  3. Powerful sequencing capabilities and effective methods: advanced PacBio and Illumina sequencing platforms.
  4. Keep up with the frontiers of bioinformatics analysis, evolutionary genomics and molecular epidemiology.

 

Microbial iso-seq is becoming more and more important in basic research. It accurately describes the diversity of transcriptional isoforms and further provides key information about the functional biology of the genome to develop the potential applications of these abundant microorganisms in disease, medicine, agriculture, and the environment. For example, predict resistance to specific antibiotics, quantify changes in gene expression, understand the immune interaction between the host and pathogens, and track disease progression.

 

About MicrobioSeq Divison of CD Genomics

MicrobioSeq is the microbial genomics division of CD Genomics, which is a genomics service company with a good reputation for providing reliable microbial sampling products, microbial testing services, microbial genomics services, and integrated bioinformatics services.