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BOC RNA Expands Its Oligo Synthesis Services for Biomedical Research

November 21, 2021

BOC RNA, a New York-based pharmaceutical raw material supplier specializing in RNA products and their applications in disease treatment, recently announced the expansion of its oligo synthesis services to meet the needs of more customers in the biomedical industry.


Oligonucleotides, or oligos, are most commonly used as antisense oligonucleotides, small interfering RNAs, primers for DNA sequencing and amplification, probes for molecular detection of complementary DNA or RNA, and artificial gene synthesis. Oligonucleotide synthesis is the chemical synthesis of relatively short nucleic acid fragments with a defined chemical structure (sequence). BOC RNA offers diversified oligonucleotides and derivative synthesis services, including natural DNA, siRNA, mRNA, DNA/RNA oligos, as well as non-natural and more stable oligonucleotides (GMP grade and non-cGMP grade).


Custom DNA Synthesis

Enzymes synthesize DNA and RNA only in the 5' to 3'direction, while chemical oligonucleotide synthesis overcomes this shortcoming. Opposite to biosynthesis, chemical synthesis proceeds in the 3' to 5' direction, bringing high efficiency to the synthesis process. BOC RNA, by adopting chemical sythesis, rises to be the superior DNA synthesis service provider. Besides, BOC RNA can customize unmodified DNA in a variety of scales, from small-scale tailored DNA for research use to large-scale production of GMP DNA oligomers.


Custom RNA Synthesis

RNA has always been an important tool for gene function analysis and the development of new therapeutic strategies, which is widely used in biomedical research applications. BOC RNA provides unmodified RNA, modified RNA, chimeric oligonucleotides with mixed DNA and RNA bases, 2'-OMe-RNA, 2'-F-RNA, and others with various labeling, modifications, and scales.


Custom mRNA Synthesis

BOC RNA offers GMP-grade mRNA to fulfill the demands of researchers, enabling them to synthesize and introduce mRNA modifications to generate transcripts suitable for downstream applications.


Antisense Oligos Synthesis

BOC RNA expands its services to antisense oligonucleotide synthesis based on customers' diverse applications in the fields of biology, diagnostics, and drug discovery. Antisense oligonucleotides are 15-25 base oligonucleotides that are designed to be antisense to the target RNA. RNase H cleavage of RNA can be mediated by antisense oligonucleotides hybridizing with target RNA, blocking the function of non-coding RNA (such as miRNA, siRNA, piRNA, snoRNA, snRNA, exRNA, scaRNA, and lncRNA) or halting mRNA translation.


Advantages of BOC RNA

  • Flexible synthesis specifications
  • Comprehensive modifications & labeling
  • Advanced high-throughput production equipment
  • Experienced team
  • Competitive price
  • Fast delivery
  • A trusted and well-known contract manufacturing partner


More information about BOC RNA's RNA-related products and services can be found at the website:



BOC RNA, a sub-brand of BOC Sciences, mainly engages in the research of RNA technology and its uses in disease treatment. It offers comprehensive RNA-related products and services, including siRNA design, synthesis, analysis, coupling, delivery, and mRNA vaccines, covering all development processes of RNA drugs. BOC RNA has been committed to providing high-quality oligo-nucleic acid synthesis and formulation services for global partners over the years.