• ISO Releases Standard Genome Editing Vocabulary

    Bio-IT World | The International Organization for Standardization has released the genome editing standard vocabulary, comprising 42 terms and definitions covering genome editing concepts, tools, and outcomes. Samantha Maragh, leader of the Genome Editing Program at the National Institute of Standards and Technology, says the goal now is adoption.

    Sep 6, 2022
  • High-Throughput Method Finds Migrating Gut Bugs That Activate Immune Cells

    Bio-IT World | Investigators at Cedars-Sinai and the National Institute of Allergy and Infectious Diseases have used high throughput sequencing and human serum to characterize the reactivities of immunoglobulin G to microorganisms in the gastrointestinal tract that crossed the intestinal mucosal barrier. The novel technique for identifying translocating gut bacteria sheds light on the interactions between the host and its gut microbiota.

    Sep 1, 2022
  • Bristol Myers Squibb’s AI Pathology Models, New Discovery Cohort for Parkinson’s Disease, More

    Bio-IT World | A new gene-editing technology center opens in Pittsburgh; phage-derived gene delivery vehicles create central nervous system genetic medicines; a new CAR-T cell therapy aims to help people with HIV; and more.

    Aug 31, 2022
  • FDA Seeks to Temper Animal Testing with Advisement from Science Board

    Bio-IT World | Lawmakers and animal welfare groups are calling for the FDA to abolish animal testing requirements for products under its jurisdiction.

    Aug 30, 2022
  • Follow the Money: Designer Precision Cancer Medicines, Biotech Workforce Development Program, More

    Bio-IT World | AI-enabled drug discovery and sustainable development, a novel antitumor glioma platform, virtual reality operating theaters, and more.

    Aug 30, 2022
  • Patient-Derived Tumor Organoids Demonstrate Microbial Influence on Immune Function

    Bio-IT World | Researchers from the Wake Forest Institute for Regenerative Medicine and Wake Forest Organoid Research Center developed an immunoreactive tumor organoid to study microbial metabolites and their effect on immune function.

    Aug 25, 2022
  • Fluorescence-Quenched Substrates Measure Parkinson’s Disease-Related Enzymes

    Bio-IT World | Though Parkinson’s is the second most common neurodegenerative disease, scientists know little about its etiology. Hoping to discover more, a research team at Simon Fraser University in Burnaby, British Columbia, developed a new fluorescence-based blood testing method to examine PD development and progression in neurons.

    Aug 24, 2022
  • Self-Boosting Vaccines Are Near At Hand

    Bio-IT World | Researchers at the Massachusetts Institute of Technology have been working on “self-boosting” vaccines for a decade now. Thanks to the COVID-19 pandemic, curiosity about the underlying platform has piqued in First World nations where vaccination boosters now have personal everyday relevance.

    Aug 24, 2022
  • A Roadmap to Real-World Data in Drug Discovery

    Bio-IT World | Victoria Gamerman’s love of analytics and math came from her grandmother—the first mathematician she knew. Now, as the Global Head of Data Governance and Insights at Boehringer Ingelheim, she’s using that love for data to explore real-world data for drug discovery.

    Aug 23, 2022
  • Survey Suggests Alzheimer’s Research Is Missing the Boat

    Bio-IT World | A research team is advocating for a more data-driven approach to Alzheimer’s research where sets of biological pathways get grouped with mechanisms the body itself uses to ward off the disease.

    Aug 18, 2022
  • Metabolomics Crucial To Personalizing Lung Cancer Therapy

    Bio-IT World | A popular hypothesis in oncology research over the past few years is that immunotherapy works synergistically with glutaminase inhibition. Banking on that assumption, clinical trials have launched to evaluate the combination approach in patients with non-small cell lung cancer.

    Aug 17, 2022
  • Long COVID and Chronic Fatigue Syndrome Have A Lot In Common

    Bio-IT World | Evidence is emerging that long COVID (formally “post-acute sequelae SARS-CoV-2 infection,” or PASC) bears a striking, molecular-level resemblance to the disabling and complex illness now known as myalgic encephalomyelitis/chronic fatigue syndrome.

    Aug 16, 2022
  • Classification System For Colorectal Cancer Needs An Update

    Bio-IT World | A multi-national team of clinicians and scientists has determined that the consensus molecular subtype (CMS) classification of colorectal cancer needs updating to better reflect the molecular underpinnings of the disease.

    Aug 11, 2022
  • GA4GH Phenopackets Standard Published By ISO

    Bio-IT World | The International Organization for Standardization (ISO) has published Phenopackets, a standard initially developed by the Global Alliance for Genomics and Health and championed at ISO under the Canadian Mirror Committee to ISO/TC215/SC1 Genomics informatics, and supported by the Standards Council of Canada.

    Aug 10, 2022
  • Online ‘Biclustering’ Tool Stratifies Patients To The Molecular Level

    Bio-IT World | Researchers in Germany have developed a web-based tool, powered by machine learning, which extracts disease subtypes from large pools of patient data. The goal is more precise and robust predictions about molecular signatures that can serve as a starting point for investigating disease heterogeneity.

    Aug 9, 2022
  • How Deleted and Siloed Data Are Slowing Discovery

    Bio-IT World | Though advancements in instruments and software have driven life sciences breakthroughs that drastically improve global health outcomes, researchers still struggle to maximize the value of the huge datasets that these high-throughput technologies generate. Currently, two common practices stand in the way of good data management at many life sciences institutions.

    Aug 5, 2022
  • Bio-IT World Announces European Best of Show Awards

    Bio-IT World | Bio-IT World is bringing the Best of Show competition to Europe this fall at the Bio-IT World Conference & Expo Europe in Berlin, October 18-19.

    Aug 3, 2022
  • Electrical Tissue Dissociation Outperforms Mechanical, Chemical Approaches

    Bio-IT World | A team of researchers from Brown University are in the process of developing a simple, inexpensive, portable device to electrically dissociate tissues into viable single cells. They’ve published the work in Scientific Reports, and foresee the approach being useful in both clinical diagnostics and basic scientific research.

    Aug 2, 2022
  • Target Discovery Engine for ALS, DRAGEN Update, Anti-Aging Analytic Software, More

    Bio-IT World | Merck announces a Digital Sciences Studio to support early-stage biomedical startups; a new suite of informatics tools anticipates pharmaceutical manufacturing bottlenecks; Novartis Pharmaceuticals UK announces the Novartis Biome UK Heart Health Catalyst 2022 Initiative; and more.

    Jul 28, 2022
  • Follow the Money: Lipid Nanoparticle Delivery Platform, Regulatory RNA Targeting, More

    Bio-IT World | Funding for Pylera commercial rights, in vivo biologics design platform, precision cancer therapy, and more.

    Jul 27, 2022