• Survey Suggests Alzheimer’s Research Is Missing the Boat

    Bio-IT World | A research team is advocating for a more data-driven approach to Alzheimer’s research where sets of biological pathways get grouped with mechanisms the body itself uses to ward off the disease.

    Aug 18, 2022
  • Metabolomics Crucial To Personalizing Lung Cancer Therapy

    Bio-IT World | A popular hypothesis in oncology research over the past few years is that immunotherapy works synergistically with glutaminase inhibition. Banking on that assumption, clinical trials have launched to evaluate the combination approach in patients with non-small cell lung cancer.

    Aug 17, 2022
  • Long COVID and Chronic Fatigue Syndrome Have A Lot In Common

    Bio-IT World | Evidence is emerging that long COVID (formally “post-acute sequelae SARS-CoV-2 infection,” or PASC) bears a striking, molecular-level resemblance to the disabling and complex illness now known as myalgic encephalomyelitis/chronic fatigue syndrome.

    Aug 16, 2022
  • Classification System For Colorectal Cancer Needs An Update

    Bio-IT World | A multi-national team of clinicians and scientists has determined that the consensus molecular subtype (CMS) classification of colorectal cancer needs updating to better reflect the molecular underpinnings of the disease.

    Aug 11, 2022
  • GA4GH Phenopackets Standard Published By ISO

    Bio-IT World | The International Organization for Standardization (ISO) has published Phenopackets, a standard initially developed by the Global Alliance for Genomics and Health and championed at ISO under the Canadian Mirror Committee to ISO/TC215/SC1 Genomics informatics, and supported by the Standards Council of Canada.

    Aug 10, 2022
  • Online ‘Biclustering’ Tool Stratifies Patients To The Molecular Level

    Bio-IT World | Researchers in Germany have developed a web-based tool, powered by machine learning, which extracts disease subtypes from large pools of patient data. The goal is more precise and robust predictions about molecular signatures that can serve as a starting point for investigating disease heterogeneity.

    Aug 9, 2022
  • How Deleted and Siloed Data Are Slowing Discovery

    Bio-IT World | Though advancements in instruments and software have driven life sciences breakthroughs that drastically improve global health outcomes, researchers still struggle to maximize the value of the huge datasets that these high-throughput technologies generate. Currently, two common practices stand in the way of good data management at many life sciences institutions.

    Aug 5, 2022
  • Bio-IT World Announces European Best of Show Awards

    Bio-IT World | Bio-IT World is bringing the Best of Show competition to Europe this fall at the Bio-IT World Conference & Expo Europe in Berlin, October 18-19.

    Aug 3, 2022
  • Electrical Tissue Dissociation Outperforms Mechanical, Chemical Approaches

    Bio-IT World | A team of researchers from Brown University are in the process of developing a simple, inexpensive, portable device to electrically dissociate tissues into viable single cells. They’ve published the work in Scientific Reports, and foresee the approach being useful in both clinical diagnostics and basic scientific research.

    Aug 2, 2022
  • Target Discovery Engine for ALS, DRAGEN Update, Anti-Aging Analytic Software, More

    Bio-IT World | Merck announces a Digital Sciences Studio to support early-stage biomedical startups; a new suite of informatics tools anticipates pharmaceutical manufacturing bottlenecks; Novartis Pharmaceuticals UK announces the Novartis Biome UK Heart Health Catalyst 2022 Initiative; and more.

    Jul 28, 2022
  • Follow the Money: Lipid Nanoparticle Delivery Platform, Regulatory RNA Targeting, More

    Bio-IT World | Funding for Pylera commercial rights, in vivo biologics design platform, precision cancer therapy, and more.

    Jul 27, 2022
  • The Gift of the Outlier: George Church on Neurodiversity, Collision of Bad Ideas, and Thinking Visually

    Bio-IT World | In the latest episode of Bio-IT World’s Trends from the Trenches podcast, host Stan Gloss, founder of BioTeam, talks with George Church about how neurodiversity has shaped his education and scientific career and how a trait they share—dyslexia—leads to some out-of-the-box thinking.

    Jul 26, 2022
  • Inaugural Illumina Genomics Forum Hosts Former U.S. President Barack Obama

    Bio-IT World | Illumina announced the inaugural Illumina Genomics Forum, a global event championing the positive impact of genomic health. From September 28 through October 1, genomics, healthcare, and health policy innovators will convene to discuss how genomic tech fosters better predictive care, diagnoses, and therapeutics.

    Jul 21, 2022
  • TetraScience Announces GxP Solution, $500M Investment in Scientific Data Cloud

    Bio-IT World | Today, TetraScience announces the expansion of the Tetra Scientific Data Cloud to include manufacturing and quality control (QC) data and pledges $500 million over the next five years to further development.

    Jul 20, 2022
  • AI-Powered Microbial Mapping Paves the Way for Designer Gut Microbiomes

    Bio-IT World | A team of biologists and engineers from the Universities of Michigan and Wisconsin used a synthetic human gut microbiome to study the interactions between intestinal microbial communities. Their findings lay the groundwork for designer microbiomes with target functions.

    Jul 19, 2022
  • Automating the Genomic Medicines of the Future

    Bio-IT World | Historically, the heavily regulated biopharma industry has been slow to adopt new technologies. However, a shift toward automation is vital to ensure that next-generation solutions produce at scale.

    Jul 15, 2022
  • Oak Ridge Researchers ID Proteins that Can Block Tumor Growth Pathway

    Bio-IT World | Researchers at the Department of Energy’s Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins to the activation—and deactivation—of the c-MET pathway, which leads to the progression of tumor growth and metastatic cancer cells. Mutating any of four proteins blocks pathway progression.

    Jul 14, 2022
  • St. Jude Sickle Cell Research Team Warns Geneticists to Choose ‘the Right Mouse for the Job’

    Bio-IT World | Mitchell Weiss and fellow St. Jude team members devised autologous hematopoietic stem cell gene-editing techniques with hopes of curing sickle cell disease, but not without the “right mouse for the job.”

    Jul 12, 2022
  • For Drug Discovery Research, Laboratory Automation Needs to Be Flexible

    Bio-IT World | Scientists who want to implement automation in their laboratories should choose an infrastructure that can provide long-term flexibility for their teams. Increasing productivity with automation is essential to make that vision possible, and flexibility is critical for researchers to change workflows and take on new priorities quickly.

    Jul 8, 2022
  • Drug Repurposing Strategy Without An ‘Answer Book’

    Bio-IT World | Scientists working in the information biology lab at Hokkaido University in Japan have come up with a drug repurposing strategy combining machine learning, unsupervised clustering of gene expression, and two-stage prediction.

    Jul 7, 2022