• Digital Patients Could Help More Drugs Reach Market

    Bio-IT World | Clinical trials employing digital representations of patients and running in parallel with actual clinical trials could soon help researchers understand what separates responders and nonresponders to a drug.

    Jun 22, 2021
  • H3’s Data Centric Approach to Cancer Genomics

    Bio-IT World | Lihua Yu took on the role of President of H3 three years ago; she oversees R&D and corporate development operations. She discusses her career trajectory and how the ideas and technologies fueling precision medicine have evolved since she joined H3.

    Jun 22, 2021
  • Snthesis Launches with Data Harmonization Lessons Learned From the Web

    Bio-IT World | As the life sciences industry seeks to manage—and fruitfully mine—more and more data, data harmonization is a bit of a nagging thorn. Snthesis launched this year, applying lessons learned from the Semantic Web to knowledge graphs for life sciences.

    Jun 17, 2021
  • Molecular Tweezers Found To Attack Antibiotic-Resistant Bacteria

    Bio-IT World | An international team of researchers has come up with a new application for “molecular tweezers” originally developed to untangle the amyloid nanofibers found in the brain of patients with Alzheimer’s and Parkinson’s disease. As it turns out, the tiny synthetic molecules may also be a way to prevent and treat bacterial infections like Staphylococcus aureus that have grown resistant to antibiotics

    Jun 16, 2021
  • Gamifying Vision: How Mobile Gaming Is Tracking Vision Degradation in Patients

    Bio-IT World | Tilak Healthcare aims to combine video games with medical expertise so that the same vision monitoring tools that are reliable and useful for doctors will be playful and fun for users. If Tilak can achieve that, the company tools will be “sticky” enough to have a longstanding impact on the healthcare process for patients.

    Jun 15, 2021
  • DNA Data Storage Alliance Makes Its Case in New White Paper, Website

    Bio-IT World | The DNA Data Storage Alliance, an organization formed last year by Twist Bioscience Corporation, Illumina, and Western Digital together with Microsoft Research, has launched its website and released its first white paper, an introduction to DNA data storage, endorsed by 29 member organizations.

    Jun 10, 2021
  • Achieving AI: Pharma’s Digital Transformation Pathway

    Bio-IT World | What does it mean for a pharmaceutical company to be digital and how do we get there? That’s what Reza Olfati-Saber, PhD, Global Head AI & Deep Analytics, Digital & Data Science R&D, at Sanofi tackled yesterday at the DECODE: AI for Pharmaceuticals forum.

    Jun 10, 2021
  • Biology’s Role As A Driver of the Future of Computation Development

    Bio-IT World | At the DECODE: AI for Pharmaceuticals forum yesterday, Puneet Batra, director of machine learning at the Broad Institute, outlined the mission of the new Eric and Wendy Schmidt Center at the Broad: to position biology to drive the next era of computing.

    Jun 9, 2021
  • Biotechs, Pharma Talk Cloud at AWS Symposium

    Bio-IT World | At the AWS Healthcare and Life Sciences symposium last week, several biotech, pharma, and genomics organizations presented their cloud-enabled workflows and highlighted how Amazon Web Services is enabling their research and efforts.

    Jun 8, 2021
  • Data Vision: How Pharma’s View of Data is Changing Healthcare

    Bio-IT World | Kicking off the DECODE: AI for Pharmaceuticals forum held virtually this week, speakers from big pharma discussed the cultural challenges required to become a data-driven business and how doing so might position us for the next horizon in personalized medicine.

    Jun 8, 2021
  • New Fund for Early-Stage Life Sciences, Microscopy for Protein Dynamics: Follow the Money

    Bio-IT World | AI for gene therapy, gastrointestinal disease, and other indications, VAST Data’s disaggregation of hardware and software, targeting transcription factors as druggable regions, a new approach to sharing computational research, and more.

    Jun 3, 2021
  • The FDA Doesn’t Show Signs of Slowing Down – How Can Pre-Revenue Life Sciences Companies Keep Up?

    Bio-IT World | With the FDA working at a record pace, how can life sciences companies keep up and effectively move through the drug development life cycle? Answer: A robust technology solution that enables granular tracking of spending and scale as the as the company rapidly grows and moves through the four main stages of drug development: start-up, IPO, clinical trials, and commercialization.

    Jun 2, 2021
  • New Pandemic Sciences Centre, Alliances on Health, New Products

    Bio-IT World | University of Oxford launches a new Pandemic Sciences Centre, Sema4 partners with AdventHealth, IQVIA reports on R&D trends, American Heart Association allies with Hitachi Vantara, Biogen and Ginkgo pursue a novel gene therapy manufacturing platform, and new products from TripleBlind, Twist Bioscience.

    Jun 1, 2021
  • Becoming Data-Driven Across International Borders: Key Translation Considerations

    Bio-IT World | Big data is often used by businesses to analyze and expand into foreign markets, but there are added complexities when it comes to processing data that crosses international borders. Gathering data in multiple languages layers complexity onto any research.

    May 28, 2021
  • New PK Model Takes Some Of The Guesswork Out Of Pediatric Dosing

    Bio-IT World | A machine learning specialist in Finland is developing an algorithm for determining drug dosing in children at various stages of maturation, which could one day aid in the design of pediatric clinical trials having a small number of participants.

    May 27, 2021
  • Next-Gen Antiviral Agents Block Function Of Untranslated RNA

    Bio-IT World | One promising new way of stopping a viral pathogen from replicating is with drugs attacking the genetic information on the virus itself—its RNA. Efforts up to now have focused on targeting a virus’s proteins, but researchers in the UK have identified cylindrically shaped molecules that can block the function of untranslated RNA.

    May 26, 2021
  • Vizgen Launches Data Release Program, Shares Spatial Genomics Mouse Brain Map

    Bio-IT World | Vizgen has released its first freely-available dataset as part of its newly-launched Vizgen Data Release Program. The Vizgen MERFISH Mouse Brain Receptor Map is an open-source spatial genomics dataset containing the exact position of transcripts from 483 genes across three full coronal slices with three biological replicates for each slice.

    May 20, 2021
  • Mount Sinai Moving Genomics Into Clinical Care

    Bio-IT World | The Institute for Genomic Health at Mount Sinai Health System is launching pilot programs in the clinic based on discoveries from genomic research to evaluate their real-world utility. Where genomics data proves useful, the necessary infrastructure then gets built in terms of educating medical professionals and creating navigational paths for patients to bring that information to bear in clinical decision-making.

    May 19, 2021
  • Five-Year Plan: The Changing Landscape of Science, Storage

    Bio-IT World | Glenn Lockwood serves as a storage architect at the National Energy Research Scientific Computing Center based at Lawrence Berkeley National Laboratory. In this role, he’s had a front-row seat to the changing demands of science on storage.

    May 18, 2021
  • AI and the Lab of the Future

    Bio-IT World | The laboratory of the future does not look at all like what we think of today but will instead be a network of physical and virtual spaces, spanning the entire lifecycle of therapeutic products. Robot-guided molecular and cellular biology labs test predictions of new chemicals generated in the cloud. Biomarkers derived from organs on a chip and federated global clinical trials yield patient-precise clinician reports. Sensors monitor compliance and collect troves of data over time. In fact, all of these technologies are here today, but the laboratory of the future will learn to connect them into constellations of discovery.

    May 14, 2021