• Next-Gen Antiviral Agents Block Function Of Untranslated RNA

    Bio-IT World | One promising new way of stopping a viral pathogen from replicating is with drugs attacking the genetic information on the virus itself—its RNA. Efforts up to now have focused on targeting a virus’s proteins, but researchers in the UK have identified cylindrically shaped molecules that can block the function of untranslated RNA.

    May 26, 2021
  • Vizgen Launches Data Release Program, Shares Spatial Genomics Mouse Brain Map

    Bio-IT World | Vizgen has released its first freely-available dataset as part of its newly-launched Vizgen Data Release Program. The Vizgen MERFISH Mouse Brain Receptor Map is an open-source spatial genomics dataset containing the exact position of transcripts from 483 genes across three full coronal slices with three biological replicates for each slice.

    May 20, 2021
  • Mount Sinai Moving Genomics Into Clinical Care

    Bio-IT World | The Institute for Genomic Health at Mount Sinai Health System is launching pilot programs in the clinic based on discoveries from genomic research to evaluate their real-world utility. Where genomics data proves useful, the necessary infrastructure then gets built in terms of educating medical professionals and creating navigational paths for patients to bring that information to bear in clinical decision-making.

    May 19, 2021
  • Five-Year Plan: The Changing Landscape of Science, Storage

    Bio-IT World | Glenn Lockwood serves as a storage architect at the National Energy Research Scientific Computing Center based at Lawrence Berkeley National Laboratory. In this role, he’s had a front-row seat to the changing demands of science on storage.

    May 18, 2021
  • AI and the Lab of the Future

    Bio-IT World | The laboratory of the future does not look at all like what we think of today but will instead be a network of physical and virtual spaces, spanning the entire lifecycle of therapeutic products. Robot-guided molecular and cellular biology labs test predictions of new chemicals generated in the cloud. Biomarkers derived from organs on a chip and federated global clinical trials yield patient-precise clinician reports. Sensors monitor compliance and collect troves of data over time. In fact, all of these technologies are here today, but the laboratory of the future will learn to connect them into constellations of discovery.

    May 14, 2021
  • Tailocins Play Starring Role In Atomic-Level Horror Show

    Bio-IT World | Large protein nanomachines produced by bacteria to selectively annihilate other members of their microbial community could one day be weaponized for wiping out undesirable inhabitants of the human microbiome known to cause ill health and disease.

    May 13, 2021
  • St Jude Releases Early Data on Asymptomatic Cases Among Vaccinated Healthcare Workers

    Bio-IT World | In a research letter published last week in JAMA, St Jude Children’s Research Hospital researchers reported early findings tracking asymptomatic COVID-19 among vaccinated healthcare workers. The findings will inform both individual vaccination plans as well as institutional screening and testing programs.

    May 13, 2021
  • Value Of Drug Repurposing May Lie In Host-Directed Therapies

    Bio-IT World | The University of California, San Francisco’s (UCSF) Quantitative Biosciences Institute (QBI) spearheaded a six-nation collaborative around COVID-19 that now has 26 potential treatments in clinical trials.

    May 10, 2021
  • Human Biospecimen Procurement Should Be More User Friendly

    Bio-IT WorldWhile the vast majority of R&D procurement may never be as easy as point-and-click, we can look to consumer marketplaces for ideas on how to improve the overall life science buying experience.

    May 6, 2021
  • Could Death Receptor 5 Antibodies Make A Comeback?

    Bio-IT World | Big pharma has invested billions of dollars in developing antibodies targeting death receptor 5 (DR5) over the years in hopes of improving the survival of patients with cancer. While promising when tested in mice in the lab, they invariably failed to show efficacy during phase 2 clinical studies. But researchers at the University of Virginia now have a new theory that could revive them.

    May 4, 2021
  • Sequencing Project for Developmental Differences, New Data Management Tools, Hyperscale Storage, More

    Bio-IT World | NIH grant tackles COVID-19 disparities, St. Jude launches historic expansion, Illumina all in on African Pathogen Genomics Initiative, and new platforms and services to ease drug and vaccine development. Plus: new storage from VAST Data, and new solutions for tracking research papers and patents.

    May 3, 2021
  • Big Money for Gene Editing, Engineering, Structure-Based Drug Design, and Data Management

    Bio-IT World | Illumina joins the Gates Foundation in a global pathogen genomics initiative, new money for immune profiling, and Benchling nets $200M for their cloud platform.

    Apr 29, 2021
  • Understanding Proteins With Natural Language Processing

    Bio-IT World | New research from the departments of chemistry and physics at Cambridge University has just helped demonstrate the potential of natural language processing (NLP) for understanding biomolecular condensates.

    Apr 28, 2021
  • New Event Launching in June Focusing on AI for Pharmaceuticals

    Bio-IT World | Bio-IT World and AI Trends are pleased to announce DECODE: AI for Pharmaceuticals, June 7-9, 2021, the first cross-functional conference to uncover AI’s true value for the pharmaceutical sector, while also focusing on data strategies, organizational change management, and implementation best practices.

    Apr 26, 2021
  • Why Prioritizing Genomic Research Is Critical for The Future of Healthcare

    Bio-IT World | Over the past 20 years, the field of genomics has undergone significant progress and transformation. We are at an exciting juncture in this field; however, there is more to be done to ensure more equitable access to technologies and support researchers around the world.

    Apr 23, 2021
  • Bioinformatics Platform Designs Therapies Against Multi-Drug Resistant Bacteria

    Bio-IT World | A Johns Hopkins University team has published details of their Facile Accelerated Specific Therapeutic (FAST) platform in Nature Communications Biology, a platform designed to address antibiotic resistance.

    Apr 22, 2021
  • How COVID-19 Is Changing the Sequencing Landscape

    Bio-IT World | The pandemic has prompted diverse scientific groups to take on sequencing in the US—and for many, the new technology has brought additional challenges to overcome. But these NGS-newbies are learning and will change biology beyond COVID-19.

    Apr 20, 2021
  • COVID-19 Highlights the Need for Interoperability in Healthcare

    Bio-IT World | In healthcare, the primary means of collecting patient data, the electronic health record (EHR), is one of the biggest offenders of a siloed approach to data. One need look no farther than the current pandemic to see how the lack of data-sharing infrastructure has prevented healthcare providers from getting a complete picture of their patients’ medical histories and hindered research on what treatments are working against the novel coronavirus.

    Apr 16, 2021
  • Bayer’s Science@Scale Platform and the Role For NVIDIA Federated Learning

    Bio-IT World | NVIDIA has announced the next generation of federated learning: Clara 4.0 with global orchestration of edge clients, and an addition to privacy-preserving homomorphic encryption. David Ruau, VP, head of Global Data Assets and Decision Science at Bayer, outlined Bayer’s work with NVIDIA to incorporate Clara Federated Learning.

    Apr 15, 2021
  • Mutational Signatures In Cancer Improved By Supervised Machine Learning

    Bio-IT World | Researchers at the Johns Hopkins Kimmel Cancer Center have a newly developed supervised machine learning algorithm that does the best job yet of connecting tissue-specific cancers to potential disease-driving factors.

    Apr 14, 2021