• ‘Reproductive Resilience Hypothesis’ Highlights the Ovary as a Discovery Source in Longevity Research

    Bio-IT World | In research published today, scientists at the Buck Institute for Research on Aging have used inductive reasoning to come up with a “Reproductive Resilience Hypothesis” suggesting that the ovary serves as the central biological hub helping to coordinate overall health. The proposal has implications for women before and after menopause, as well as men, who stand to benefit from what might be learned about the mechanisms controlling beneficial ovarian communication.

    Aug 6, 2026

  • Trends from the Trenches: Why Semantics Matter in Life Sciences

    Bio-IT World | The AI boom has pushed life sciences data strategy into an uncomfortable spotlight: the answers look polished, but hallucinations, weak reproducibility, and fuzzy audit trails make them risky in regulated work. That pressure is why knowledge graphs, ontologies, and FAIR data principles are showing up in more conversations about AI readiness. In the latest episode of Trends from the Trenches, Tom Plasterer, CEO and co-founder, and Eric Little, chief data officer, of Knowledge3 break down what it takes to turn semantics into something practical.

    Aug 4, 2026

  • Vibrating Capsule Reveals Gut-Brain Biomarkers for Anorexia Relapse

    Bio-IT World | An ingestible vibrating capsule combined with computational modeling of gut-brain signaling may help identify patients with anorexia nervosa (AN) at risk of relapse while opening the door to new therapeutic strategies.

    Aug 4, 2026

  • Beyond Sequence: Building the Next Generation of Structural Genomics Platforms

    Bio-IT World | For more than three decades, genomics has been driven by a simple but extraordinarily successful premise: biological information is encoded in nucleotide sequence. Advances in sequencing technologies, genome assembly, annotation, variant analysis, and computational biology have transformed our understanding of genes and genomes.

    Jul 31, 2026

  • Follow the Money: Fresenius Expands Multiple Growth Areas, Off-the-Shelf CAR-T Therapies, Antibody for Full Season Influenza

    Bio-IT World | Beeline Medicines advances a differentiated portfolio to target underlying causes of immune-mediated diseases; Hemispheric’s platform is Descartes, the world’s first frontier NeuroAI model; and more.

    Jul 29, 2026

  • Baylor College Serves as Sequencing Center, Immunai, Boehringer Ingelheim Multi-Project Collaboration, Spatial Biology

    Bio-IT World | PumasAI helps establish the Dr. Ramalingam Sankaran Computational Lab for Quantitative Sciences at PSG Institute of Medical Sciences and Research; Novogene Europe launches its Untargeted Metabolomics Service through its Cambridge Omics Centre; and more.

    Jul 28, 2026

  • Baylor College Serves as Sequencing Center, Immunai, Boehringer Ingelheim Multi-Project Collaboration, Spatial Biology

    Bio-IT World | PumasAI helps establish the Dr. Ramalingam Sankaran Computational Lab for Quantitative Sciences at PSG Institute of Medical Sciences and Research; Novogene Europe launches its Untargeted Metabolomics Service through its Cambridge Omics Centre; and more.

    Jul 28, 2026

  • The Most Expensive AI Mistake in Biotech Isn’t a Hallucination, It’s a Process Failure

    Bio-IT World | The most expensive AI failures in biotech and pharma are unlikely to come from a model inventing a sentence. They are more likely to come from organizations treating AI as a standalone tool instead of a controlled business process. That distinction matters because regulated life sciences have spent decades building systems around process integrity.

    Jul 24, 2026

  • In Vivo CRISPR Therapy is One Step Closer to the Clinic

    Bio-IT World | A one-time, in vivo CRISPR gene-editing therapy from Intellia Therapeutics could become the first approved treatment of its kind for patients with hereditary angioedema. The experimental therapy, lonvoguran ziclumeran (lonvo-z), reduced hereditary angioedema (HAE) attacks by 87% in a phase 3 trial and could be submitted for regulatory review in the United States and Europe within the next year.

    Jul 23, 2026

  • Different Teams, Same Problem

    Bio-IT World | Receiving a Bio-IT World Best of Show Award for OmicsHQ was a tremendous honor. More importantly, it provided an opportunity to engage with the researchers, data scientists, and technology leaders who ultimately determine whether products like ours succeed or fail.

    Jul 22, 2026

  • Winning Best of Show Again: A Reflection on MLADU, Research Data, and the Bio-IT World Community

    Bio-IT World | When Dantech Corporation created MLADU, we were not trying to build a product that would win awards. We were trying to solve a problem that we kept seeing in the real world: research organizations, consortia, biopharma teams, clinical partners, and technology teams needed to move important data securely, reliably, and with accountability, but the process was often far more slow and difficult than it should be.

    Jul 21, 2026

  • With AWS Help, UK Group Moves Toward Global AMR Intelligence Platform

    Bio-IT World | Amazon Web Services has come alongside the UK’s The Fleming Initiative, offering up to several million pounds worth of cloud and AI technology, as well as technical support, for the Initiative’s global antimicrobial resistance (AMR) intelligence platform.

    Jul 16, 2026

  • CFDE Promotes Collaboration to Build Creative and Practical Solutions to Data Challenges during the Bio-IT Hackathon

    Bio-IT World | The 2026 Bio-IT FAIR Data Hackathon kicked-off the 25th Bio-IT World Conference & Expo by welcoming 32 data scientists, software developers, students, and life science professionals to address real-world data challenges using Open Source and FAIR (Findable, Accessible, Interoperable, Reusable) data principles.

    Jul 15, 2026

  • CFDE Promotes Collaboration to Build Creative and Practical Solutions to Data Challenges during the Bio-IT Hackathon

    Bio-IT World | The 2026 Bio-IT FAIR Data Hackathon kicked-off the 25th Bio-IT World Conference & Expo by welcoming 32 data scientists, software developers, students, and life science professionals to address real-world data challenges using Open Source and FAIR (Findable, Accessible, Interoperable, Reusable) data principles.

    Jul 15, 2026

  • How Sugar on Brain Cells May Be Driving Alzheimer’s and How a Common Joint Supplement May Be Making It Worse

    Bio-IT World |  While most of the research on Alzheimer’s Disease (AD) in the last few decades has focused on amyloid-beta plaques and the tau tangles—the misfolded debris cluttering and hindering normal brain function—a group at the University of Florida has identified a new angle of pursuit by performing an unbiased survey of all the different fats, sugars, and small molecule metabolites in the brains of Alzheimer’s patients.

    Jul 14, 2026

  • Signal Management Isn’t Broken; It Simply Belongs to a Previous Era

    Bio-IT World | Drug safety discussions rarely take into account how pharmacovigilance might change if the adverse event case-processing bottleneck was eliminated altogether. Yet this reality is within reach now thanks to advanced technology. As an industry we have digitized the paperwork and accelerated individual steps, but the overall workflow remains largely sequential, manual at its core, and oriented around periodic snapshots rather than continuous monitoring.

    Jul 10, 2026

  • Network Effects: John Quackenbush on How Networks Illuminate Biology Beyond Gene Expression

    Bio-IT World | A group of researchers is sounding the alarm: the publicly funded data infrastructure underpinning virtually all of modern biomedical research is fragile, underfunded, and increasingly at risk. It is up to us to safeguard it. At a session at last month’s Bio-IT World Conference & Expo, Douaa Mugahid, PhD, Data Officer at the Hi-IMPAcTB Consortium at the Harvard School of Public Health moderated a panel of academics, investors, and consultants to take on the future of public data and software infrastructure.

    Jul 9, 2026

  • Insilico Medicine Launches Phase III Trial for AI-Developed Drug

    Bio-IT World | Insilico Medicine is launching a phase III clinical program for rentosertib, its potentially first-in-class oral small-molecule inhibitor of TNIK (TRAF2- and NCK-interacting kinase) for the treatment of idiopathic pulmonary fibrosis (IPF), a progressive, age-related fibrotic lung disease with high unmet medical need. It is the next step in making AI-discovered drugs a reality for patients.

    Jul 8, 2026

  • Digital Brain Twin Tailor-Made for Autism Spectrum Disorder

    Bio-IT World | A new type of digital twin model of the brain, designed specifically for children with autism spectrum disorder, has been developed by researchers in Italy in hopes of enabling targeted treatment with transcranial magnetic stimulation at the exact location in the brain where neural circuits are misfiring. The computational feat raises the possibility of reversing the neurodevelopmental condition and exemplifies an “AI for good” application to help counterbalance fears about nefarious uses of artificial intelligence.

    Jul 7, 2026

  • Follow the Money: Inflammatory Bowel Disease Oral Drug, Breast, Colorectal Cancer ADCs, Other Next-Gen, Novel Treatments

    Bio-IT World | NewLimit plans to launch its first human clinical trial next year, testing a liver cell-reprogramming therapy; SonoThera advances its lead programs in Duchenne muscular dystrophy (DMD) and autosomal dominant polycystic kidney disease (ADPKD) into the clinic; Portal’s platform uses mechanoporation to deliver materials such as RNA, gene editors, probes, and antibodies; and more.

    Jul 1, 2026