• 5 Ways To Keep Your Life Sciences Startup From Becoming Theranos

    Bio-IT World Contributed Commentary | Transparency is critical for all industries these days, but especially for the life sciences sector. When it comes to innovative services and products from emerging life sciences companies, transparency can be pivotal to preventing fraud and wasted investments.

    Jul 18, 2019
  • How The Parker Institute Addresses Tumor-Specific T Cells

    Bio-IT World | As a Senior Data Scientist at the Parker Institute for Cancer Immunotherapy, Daniel Wells sees how discoveries in immunotherapy are rapidly changing how researchers develop treatment strategies for patients by integrating multiple molecular and clinical data types.

    Jul 17, 2019
  • Building A Marriage Between Medicine And Tech

    Bio-IT World | John-William Sidhom says the ideal scenario would be to have a system where scientific research asks the relevant questions, tech provides answers to those questions, and the physician implements those solutions for the most clinical impact.

    Jul 12, 2019
  • St. Jude Announces Availability Of Clinical Genome Sequencing Data In Real Time Via Cloud

    Bio-IT World | St. Jude Children's Research Hospital has announced the real-time availability of clinical genome sequencing data on the St. Jude Cloud.

    Jul 11, 2019
  • Genomenon Provides Quick Answers On Fusion Genes

    Bio-IT World | For decades, clinicians and researchers have been fascinated by fusion genes—genomic abnormalities that form when part of the DNA from one chromosome moves to another chromosome. This helps explain the growing popularity of the Genomenon's Mastermind suite of software tools, which is more inclusive of all documented fusions.

    Jul 10, 2019
  • How Paratope Refinement Can Mitigate Antibody Polyspecificity

    Bio-IT World | There is often a lack of understanding in drug discovery about how polyspecificity drives antibody toxicity. This shows polyspecificity is an underappreciated phenomenon in therapeutic antibody development, but that these unwanted properties can be fully improved by paratope refinement.

    Jul 3, 2019
  • MELLODDY Using Federated Learning To Improve Drug Development

    Bio-IT World | A 17-partner consortium in Europe is seeking to confirm the utility of a machine learning platform for better predicting promising compounds for drug development. The three-year initiative, which launched in June, represents the first large-scale deployment of blockchain technology to extract insights from multiple preclinical datasets without having to first pool the data.

    Jul 2, 2019
  • LabTwin, AbCellera, X4, And More: News From June 2019

    Bio-IT World | June featured exciting new, products, and partnerships from around the bio-IT community from innovating companies, organizations, and universities, including LabTwin, AbCellera, X4, and more.

    Jul 1, 2019
  • The RGC UK Biobank Consortium Data Delivery And Cohort Browser

    Bio-IT World | The Regeneron Genetics Center has undertaken the exome sequencing and analysis of 500,000 samples from the UK Biobank, using the DNAnexus Platform to host the dataset and run Regeneron’s software pipeline. To increase the value to the RGC UKB consortium, Regeneron and DNAnexus partnered to construct a combined database of the UKB genomic and phenotypic data to explore through an innovative user interface.

    Jun 28, 2019
  • AbbVie, Discngine Collaborate On Structure-Based Drug Discovery Explorer

    Bio-IT World | Although wildly used, rational structure-based drug design techniques are far from being applied to their fullest potential. AbbVie and Discngine addressed the pitfalls by co-developing a web-based structural knowledge management solution called 3decision.

    Jun 26, 2019
  • Sentieon's 'Faster/Cheaper' Genomics Tools

    Bio-IT World | Sentieon's DNAseq and TNseq software, are making waves in the life sciences, creating a "drop in replacement" that is a faster and cheaper alternative to the industry standard for secondary analysis in next-generation sequencing (NGS) data processing while producing the industry standard results.

    Jun 25, 2019
  • Tracking The Clinical And Preclinical Progress In Targeting Membrane Proteins

    Bio-IT World | G protein-coupled receptors (GPCRs), ion channels, and transporters represent some of the most important drug target classes across a wide range of diseases. According to Catherine Hutchings, progress in targeting these membrane proteins requires a recognition of not only what works, but also what doesn't.

    Jun 24, 2019
  • Officials Say They Lack Authority To Halt CRISPR Babies Plan In Russia

    STAT | Two influential leaders in science for the first time publicly condemned a Russian biologist who said he plans to produce gene-edited babies but conceded that it was beyond their organizations’ authority to halt him from doing so.

    Jun 24, 2019
  • High-Confidence Characterization Of Small Molecule 'Unknowns': How Software Is Enabling Intelligent, High-Resolution Accurate Mass LC-MS/MS Data Acquisition

    Bio-IT World Contributed Commentary | Liquid chromatography-tandem mass spectrometry has proven to be a powerful tool for small molecule analysis. However, the identification of so-called "unknown-unknowns" is extremely challenging.

    Jun 17, 2019
  • Deep Genomics Identifies Rare Disease Targets Using AI System

    Bio-IT World News Brief | Deep Genomics' AI system has identified 1,600 rare disease targets that can be drugged using its splice-switching oligonucleotide technology.

    Jun 14, 2019
  • Biobanking: A Thing Of The Past?

    Bio-IT World | Andrew Brooks, COO at RUCDR Infinite Biologics and Professor of Genetics at Rutgers University, discusses the changes he's seen in biobanking over the last decade, including the rapid changes direct to consumer applications are bringing to research biobanks, and whether or not traditional biobanks are a thing of the past.

    Jun 13, 2019
  • Golden Helix Releases Cancer Add-On To VSClinical

    Bio-IT World News Brief | Golden Helix has announced a cancer addition to their clinical analytics product, VSClinical. This new capability will guide clinicians through the clinical assessment of somatic variants, adding workflows modeled off the guidelines issued by the Association of Molecular Pathologists.

    Jun 10, 2019
  • Organoids And Their Impact On Pre-Clinical Drug Discovery

    Bio-IT World | Pharmaceutical companies are looking for ways to save time and money in the drug discovery process. If there was a way to determine a therapy's impact in the pre-clinical process, researchers would have a better understanding of where to focus their efforts. This is where organoids come in.

    Jun 7, 2019
  • The Future Of Blockchain: The Use Cases Set To Reshape Life Sciences

    Bio-IT World Contributed Commentary | Ever since blockchain burst onto the scene a decade ago, people have continually found new—and sometimes odd—applications for the technology. Yet when it comes to the life sciences, a lack of practical applications has resulted in blockchain being considered a "hammer in search of a nail."

    Jun 5, 2019
  • 2 Chinese Babies With Edited Genes May Face Higher Risk Of Premature Death

    NPR.org | There are new concerns about the world's first genetically modified babies. It appears that the genetic variation a Chinese scientist was trying to recreate when he edited twin girls' DNA may be more harmful than helpful to health overall, according to a study published Monday.

    Jun 3, 2019