• Glioblastoma Cancer Cells ‘Starve’ Without Astrocyte Immunometabolic Support

    Bio-IT World | Tel Aviv University researchers discovered that glioblastoma cells—a highly resistant, aggressive, and deadly form of cancer—“starve” to death without immunometabolic support from astrocytes.

    Sep 20, 2022
  • Metabolomics Crucial To Personalizing Lung Cancer Therapy

    Bio-IT World | A popular hypothesis in oncology research over the past few years is that immunotherapy works synergistically with glutaminase inhibition. Banking on that assumption, clinical trials have launched to evaluate the combination approach in patients with non-small cell lung cancer.

    Aug 17, 2022
  • Long COVID and Chronic Fatigue Syndrome Have A Lot In Common

    Bio-IT World | Evidence is emerging that long COVID (formally “post-acute sequelae SARS-CoV-2 infection,” or PASC) bears a striking, molecular-level resemblance to the disabling and complex illness now known as myalgic encephalomyelitis/chronic fatigue syndrome.

    Aug 16, 2022
  • Mount Sinai Aims To Enroll One Million People In Genetic Sequencing Project

    Bio-IT World | The greater New York metropolitan area is the epicenter of an ambitious human genome sequencing research project newly launched by Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai. If the vision is realized, Mount Sinai will enroll a million patients into a study over the next five years that will sequence and analyze the DNA in their blood to tease out the role of genetics and environment on health.

    Sep 15, 2022
  • Public More Protective Of Their Health Information Than Their Biospecimens

    Bio-IT World | In the ongoing debate about whether biospecimens should be covered by human subjects research regulations, bioethicists at the University of Michigan recently added a critical datapoint in disproving one of the arguments—namely, that the public feels more protective of their biospecimens than their health information.

    Sep 14, 2022
  • Digestive Hormones Found to Significantly Influence Infectious Wound Healing

    Bio-IT World | The University of Calgary research team discovered that neutrophils and monocytes—two types of white blood cells—play distinct roles in wound healing, with digestive hormones contributing to immune function.

    Sep 13, 2022
  • Geneticists Discover Maternal Proteins with Epigenetic Influence Over Fetal Development

    Bio-IT World | Walter and Eliza Hall Institute geneticists recently discovered that epigenetic information passes from murine mother to child and has lasting effects on development and growth.

    Sep 8, 2022
  • Collaboration Uncovers New Clues About What Triggers A Stroke

    Bio-IT World | Researchers at Tulane University and Ochsner Health have characterized carotid plaque taken from patients within days of a stroke, confirming that ruptures are associated with the thinning of the fibrous cap stabilizing the fatty deposits as well as suggesting that B cells play a bigger role than has previously been appreciated.

    Sep 7, 2022
  • ISO Releases Standard Genome Editing Vocabulary

    Bio-IT World | The International Organization for Standardization has released the genome editing standard vocabulary, comprising 42 terms and definitions covering genome editing concepts, tools, and outcomes. Samantha Maragh, leader of the Genome Editing Program at the National Institute of Standards and Technology, says the goal now is adoption.

    Sep 6, 2022
  • ISO Releases Standard Genome Editing Vocabulary

    Bio-IT World | The International Organization for Standardization has released the genome editing standard vocabulary, comprising 42 terms and definitions covering genome editing concepts, tools, and outcomes. Samantha Maragh, leader of the Genome Editing Program at the National Institute of Standards and Technology, says the goal now is adoption.

    Sep 6, 2022
  • High-Throughput Method Finds Migrating Gut Bugs That Activate Immune Cells

    Bio-IT World | Investigators at Cedars-Sinai and the National Institute of Allergy and Infectious Diseases have used high throughput sequencing and human serum to characterize the reactivities of immunoglobulin G to microorganisms in the gastrointestinal tract that crossed the intestinal mucosal barrier. The novel technique for identifying translocating gut bacteria sheds light on the interactions between the host and its gut microbiota.

    Sep 1, 2022
  • Bristol Myers Squibb’s AI Pathology Models, New Discovery Cohort for Parkinson’s Disease, More

    Bio-IT World | A new gene-editing technology center opens in Pittsburgh; phage-derived gene delivery vehicles create central nervous system genetic medicines; a new CAR-T cell therapy aims to help people with HIV; and more.

    Aug 31, 2022
  • FDA Seeks to Temper Animal Testing with Advisement from Science Board

    Bio-IT World | Lawmakers and animal welfare groups are calling for the FDA to abolish animal testing requirements for products under its jurisdiction.

    Aug 30, 2022
  • Follow the Money: Designer Precision Cancer Medicines, Biotech Workforce Development Program, More

    Bio-IT World | AI-enabled drug discovery and sustainable development, a novel antitumor glioma platform, virtual reality operating theaters, and more.

    Aug 30, 2022
  • Patient-Derived Tumor Organoids Demonstrate Microbial Influence on Immune Function

    Bio-IT World | Researchers from the Wake Forest Institute for Regenerative Medicine and Wake Forest Organoid Research Center developed an immunoreactive tumor organoid to study microbial metabolites and their effect on immune function.

    Aug 25, 2022
  • Fluorescence-Quenched Substrates Measure Parkinson’s Disease-Related Enzymes

    Bio-IT World | Though Parkinson’s is the second most common neurodegenerative disease, scientists know little about its etiology. Hoping to discover more, a research team at Simon Fraser University in Burnaby, British Columbia, developed a new fluorescence-based blood testing method to examine PD development and progression in neurons.

    Aug 24, 2022
  • Self-Boosting Vaccines Are Near At Hand

    Bio-IT World | Researchers at the Massachusetts Institute of Technology have been working on “self-boosting” vaccines for a decade now. Thanks to the COVID-19 pandemic, curiosity about the underlying platform has piqued in First World nations where vaccination boosters now have personal everyday relevance.

    Aug 24, 2022
  • A Roadmap to Real-World Data in Drug Discovery

    Bio-IT World | Victoria Gamerman’s love of analytics and math came from her grandmother—the first mathematician she knew. Now, as the Global Head of Data Governance and Insights at Boehringer Ingelheim, she’s using that love for data to explore real-world data for drug discovery.

    Aug 23, 2022
  • Survey Suggests Alzheimer’s Research Is Missing the Boat

    Bio-IT World | A research team is advocating for a more data-driven approach to Alzheimer’s research where sets of biological pathways get grouped with mechanisms the body itself uses to ward off the disease.

    Aug 18, 2022
  • Classification System For Colorectal Cancer Needs An Update

    Bio-IT World | A multi-national team of clinicians and scientists has determined that the consensus molecular subtype (CMS) classification of colorectal cancer needs updating to better reflect the molecular underpinnings of the disease.

    Aug 11, 2022