• Biology’s Role As A Driver of the Future of Computation Development

    Bio-IT World | At the DECODE: AI for Pharmaceuticals forum yesterday, Puneet Batra, director of machine learning at the Broad Institute, outlined the mission of the new Eric and Wendy Schmidt Center at the Broad: to position biology to drive the next era of computing.

    Jun 9, 2021
  • Biotechs, Pharma Talk Cloud at AWS Symposium

    Bio-IT World | At the AWS Healthcare and Life Sciences symposium last week, several biotech, pharma, and genomics organizations presented their cloud-enabled workflows and highlighted how Amazon Web Services is enabling their research and efforts.

    Jun 8, 2021
  • Data Vision: How Pharma’s View of Data is Changing Healthcare

    Bio-IT World | Kicking off the DECODE: AI for Pharmaceuticals forum held virtually this week, speakers from big pharma discussed the cultural challenges required to become a data-driven business and how doing so might position us for the next horizon in personalized medicine.

    Jun 8, 2021
  • New Fund for Early-Stage Life Sciences, Microscopy for Protein Dynamics: Follow the Money

    Bio-IT World | AI for gene therapy, gastrointestinal disease, and other indications, VAST Data’s disaggregation of hardware and software, targeting transcription factors as druggable regions, a new approach to sharing computational research, and more.

    Jun 3, 2021
  • The FDA Doesn’t Show Signs of Slowing Down – How Can Pre-Revenue Life Sciences Companies Keep Up?

    Bio-IT World | With the FDA working at a record pace, how can life sciences companies keep up and effectively move through the drug development life cycle? Answer: A robust technology solution that enables granular tracking of spending and scale as the as the company rapidly grows and moves through the four main stages of drug development: start-up, IPO, clinical trials, and commercialization.

    Jun 2, 2021
  • New Pandemic Sciences Centre, Alliances on Health, New Products

    Bio-IT World | University of Oxford launches a new Pandemic Sciences Centre, Sema4 partners with AdventHealth, IQVIA reports on R&D trends, American Heart Association allies with Hitachi Vantara, Biogen and Ginkgo pursue a novel gene therapy manufacturing platform, and new products from TripleBlind, Twist Bioscience.

    Jun 1, 2021
  • Becoming Data-Driven Across International Borders: Key Translation Considerations

    Bio-IT World | Big data is often used by businesses to analyze and expand into foreign markets, but there are added complexities when it comes to processing data that crosses international borders. Gathering data in multiple languages layers complexity onto any research.

    May 28, 2021
  • New PK Model Takes Some Of The Guesswork Out Of Pediatric Dosing

    Bio-IT World | A machine learning specialist in Finland is developing an algorithm for determining drug dosing in children at various stages of maturation, which could one day aid in the design of pediatric clinical trials having a small number of participants.

    May 27, 2021
  • Next-Gen Antiviral Agents Block Function Of Untranslated RNA

    Bio-IT World | One promising new way of stopping a viral pathogen from replicating is with drugs attacking the genetic information on the virus itself—its RNA. Efforts up to now have focused on targeting a virus’s proteins, but researchers in the UK have identified cylindrically shaped molecules that can block the function of untranslated RNA.

    May 26, 2021
  • Vizgen Launches Data Release Program, Shares Spatial Genomics Mouse Brain Map

    Bio-IT World | Vizgen has released its first freely-available dataset as part of its newly-launched Vizgen Data Release Program. The Vizgen MERFISH Mouse Brain Receptor Map is an open-source spatial genomics dataset containing the exact position of transcripts from 483 genes across three full coronal slices with three biological replicates for each slice.

    May 20, 2021
  • Mount Sinai Moving Genomics Into Clinical Care

    Bio-IT World | The Institute for Genomic Health at Mount Sinai Health System is launching pilot programs in the clinic based on discoveries from genomic research to evaluate their real-world utility. Where genomics data proves useful, the necessary infrastructure then gets built in terms of educating medical professionals and creating navigational paths for patients to bring that information to bear in clinical decision-making.

    May 19, 2021
  • Five-Year Plan: The Changing Landscape of Science, Storage

    Bio-IT World | Glenn Lockwood serves as a storage architect at the National Energy Research Scientific Computing Center based at Lawrence Berkeley National Laboratory. In this role, he’s had a front-row seat to the changing demands of science on storage.

    May 18, 2021
  • AI and the Lab of the Future

    Bio-IT World | The laboratory of the future does not look at all like what we think of today but will instead be a network of physical and virtual spaces, spanning the entire lifecycle of therapeutic products. Robot-guided molecular and cellular biology labs test predictions of new chemicals generated in the cloud. Biomarkers derived from organs on a chip and federated global clinical trials yield patient-precise clinician reports. Sensors monitor compliance and collect troves of data over time. In fact, all of these technologies are here today, but the laboratory of the future will learn to connect them into constellations of discovery.

    May 14, 2021
  • Tailocins Play Starring Role In Atomic-Level Horror Show

    Bio-IT World | Large protein nanomachines produced by bacteria to selectively annihilate other members of their microbial community could one day be weaponized for wiping out undesirable inhabitants of the human microbiome known to cause ill health and disease.

    May 13, 2021
  • St Jude Releases Early Data on Asymptomatic Cases Among Vaccinated Healthcare Workers

    Bio-IT World | In a research letter published last week in JAMA, St Jude Children’s Research Hospital researchers reported early findings tracking asymptomatic COVID-19 among vaccinated healthcare workers. The findings will inform both individual vaccination plans as well as institutional screening and testing programs.

    May 13, 2021
  • Value Of Drug Repurposing May Lie In Host-Directed Therapies

    Bio-IT World | The University of California, San Francisco’s (UCSF) Quantitative Biosciences Institute (QBI) spearheaded a six-nation collaborative around COVID-19 that now has 26 potential treatments in clinical trials.

    May 10, 2021
  • Human Biospecimen Procurement Should Be More User Friendly

    Bio-IT WorldWhile the vast majority of R&D procurement may never be as easy as point-and-click, we can look to consumer marketplaces for ideas on how to improve the overall life science buying experience.

    May 6, 2021
  • Could Death Receptor 5 Antibodies Make A Comeback?

    Bio-IT World | Big pharma has invested billions of dollars in developing antibodies targeting death receptor 5 (DR5) over the years in hopes of improving the survival of patients with cancer. While promising when tested in mice in the lab, they invariably failed to show efficacy during phase 2 clinical studies. But researchers at the University of Virginia now have a new theory that could revive them.

    May 4, 2021
  • Sequencing Project for Developmental Differences, New Data Management Tools, Hyperscale Storage, More

    Bio-IT World | NIH grant tackles COVID-19 disparities, St. Jude launches historic expansion, Illumina all in on African Pathogen Genomics Initiative, and new platforms and services to ease drug and vaccine development. Plus: new storage from VAST Data, and new solutions for tracking research papers and patents.

    May 3, 2021
  • Big Money for Gene Editing, Engineering, Structure-Based Drug Design, and Data Management

    Bio-IT World | Illumina joins the Gates Foundation in a global pathogen genomics initiative, new money for immune profiling, and Benchling nets $200M for their cloud platform.

    Apr 29, 2021