Bio-IT World | John-William Sidhom says the ideal scenario would be to have a system where scientific research asks the relevant questions, tech provides answers to those questions, and the physician implements those solutions for the most clinical impact.

Bio-IT World | St. Jude Children's Research Hospital has announced the real-time availability of clinical genome sequencing data on the St. Jude Cloud.

Bio-IT World | For decades, clinicians and researchers have been fascinated by fusion genes—genomic abnormalities that form when part of the DNA from one chromosome moves to another chromosome. This helps explain the growing popularity of the Genomenon's Mastermind suite of software tools, which is more inclusive of all documented fusions.

Bio-IT World | There is often a lack of understanding in drug discovery about how polyspecificity drives antibody toxicity. This shows polyspecificity is an underappreciated phenomenon in therapeutic antibody development, but that these unwanted properties can be fully improved by paratope refinement.

Bio-IT World | A 17-partner consortium in Europe is seeking to confirm the utility of a machine learning platform for better predicting promising compounds for drug development. The three-year initiative, which launched in June, represents the first large-scale deployment of blockchain technology to extract insights from multiple preclinical datasets without having to first pool the data.

Bio-IT World | June featured exciting new, products, and partnerships from around the bio-IT community from innovating companies, organizations, and universities, including LabTwin, AbCellera, X4, and more.

Bio-IT World | The Regeneron Genetics Center has undertaken the exome sequencing and analysis of 500,000 samples from the UK Biobank, using the DNAnexus Platform to host the dataset and run Regeneron’s software pipeline. To increase the value to the RGC UKB consortium, Regeneron and DNAnexus partnered to construct a combined database of the UKB genomic and phenotypic data to explore through an innovative user interface.

Bio-IT World | Although wildly used, rational structure-based drug design techniques are far from being applied to their fullest potential. AbbVie and Discngine addressed the pitfalls by co-developing a web-based structural knowledge management solution called 3decision.