• New Cas9 Molecule Points the Way to Viral Delivery of CRISPR Systems

    Apr 1, 2015, 14:45 PM by Michael Croft
    Bio-IT World | A paper published in today's issue of Nature demonstrates that exploring the natural diversity of CRISPR systems could lead the way to new therapeutic tools, as scientists at the Broad Institute successfully edit the genomes of mice using an AAV vector and a new Cas9 molecule derived from Staphylococcus aureus.
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  • CENTOGENE revolutionizes the clinical interpretation of rare disease genetic variants

    Apr 1, 2015, 00:00 AM by Michael Croft
    ROSTOCK, GERMANY - Apr 1, 2015 - CENTOGENE AG (“CENTOGENE”) announces the launch of the world’s largest genetic mutation database for rare diseases, CentoMD®
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  • LifeMap Solutions Teams Up with Mount Sinai on Digital Health

    Mar 31, 2015, 09:00 AM by Michael Croft
    Bio-IT World | This morning, LifeMap Solutions announced the launch of COPD Navigator, a mobile health app for people living with chronic obstructive pulmonary disease, in a pilot program conducted with Mount Sinai's Icahn Institute for Genomics and Multiscale Biology.
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  • How GitHub Apparently Ended Up In The Crosshairs Of Chinese Hackers

    Mar 31, 2015, 00:00 AM by Michael Croft
    ReadWrite | It involves dissidents hacking ways around the Great Firewall.
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  • Choosing the cloud that’s right for you

    Mar 31, 2015, 00:00 AM by Michael Croft
    Computerworld | There are degrees of commitment to the cloud, and more than one cloud model to consider.
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  • New York Genome Center Launches First LDT, Whole Exome Sequencing

    Mar 30, 2015, 14:00 PM by Michael Croft
    Bio-IT World News Brief | The New York Genome Center (NYGC) announced today that it has received approval from the New York State Department of Health to offer clinical whole exome sequencing for individuals with constitutional disorders. This is the first laboratory-developed test, or LDT, from the Center to be cleared for clinical diagnostic use.
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  • Kapa Biosystems Launches Inhibitor-Resistant qPCR Reagent Kit to Accelerate Workflows and Improve Target Amplification and Quantification of Crude Samples

    Mar 30, 2015, 00:00 AM by Michael Croft
    WILMINGTON, MA - Mar 30, 2015 - Kapa Biosystems, Inc. today announced the launch of the KAPA PROBE FORCE qPCR Kit, which contains an inhibitor-resistant DNA polymerase and master mix for improved direct target amplification and quantification of crude samples with real-time PCR
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  • Horizon Pays $1.1 Billion for Hyperion’s Rare Disease Drugs

    Mar 30, 2015, 00:00 AM by Michael Croft
    Xconomy | Big buyout for an orphan drug company. Hyperion's two therapies treat urea cycle disorder, and earned the company $113.6 million in 2014.
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  • GigaScience Paper Demonstrates Pathogen Detection on the MinION

    Mar 27, 2015, 11:00 AM by Michael Croft
    Bio-IT World News Brief | A team of researchers led by Andy Kilianski of Maryland’s Edgewood Chemical Biological Center has published a paper demonstrating the use of the MinION nanopore sequencer to accurately identify strains of bacteria and viruses.
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  • Certara Supported Risk Assessment Research Wins Outstanding Paper Award

    Mar 27, 2015, 00:00 AM by Michael Croft
    PRINCETON, NJ - Mar 27, 2015 - Certara®, the global biosimulation technology-enabled drug development and drug safety consulting company, today announced that the Toxicological Sciences article, entitled “Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-throughput Toxicity Testing,” using its Simcyp® Simulator, has been selected by the Risk Assessment Specialty Section (RASS) of the Society of Toxicology (SOT) as its “Best Published Paper Advancing the Science of Risk Assessment
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  • New Crop of Biotechs from Y Combinator

    Mar 26, 2015, 09:05 AM by Michael Croft
    Tech Crunch | This week marked Demo Day for budding companies incubated in Silicon Valley accelerator Y Combinator, which began putting out feelers for biotech startups last year and is now moving with more confidence into the biomedical field.
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  • Emerald Opens Cloud Lab Facility

    Mar 25, 2015, 16:00 PM by Michael Croft
    Bio-IT World News Brief | Emerald Therapeutics is opening its first Emerald Cloud Lab (ECL) production facility, ECL-1, in the biotech corridor of South San Francisco. The robotics life sciences laboratory was announced last year, though plans were already underway for a move to South San Francisco. Since then, the company built a new production facility from the ground up and installed over $3 million of scientific instrumentation.  
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  • deCODE Publishes Largest Human Genome Population Study

    Mar 25, 2015, 14:00 PM by Michael Croft
    Bio-IT World | With a package of four papers published today in Nature Genetics, deCODE genetics presents the largest set of  human genomes from one population, and findings including a set of complete human knockouts, a new timeline for the common Y-chromosome ancestor, and loss-of-function variants that confer Alzheimer’s disease risk.
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  • Systematic Overhaul Recommended for Human Brain Project

    Mar 24, 2015, 12:30 PM by Michael Croft
    Nature News | An independent committee reviewing the goals and practices of Europe's Human Brain Project (HBP) has substantially sided with critics of the effort, proposing major changes to the HBP's governance and to its central mission of creating a computer simulation of the human brain.
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  • Thomson Reuters Names Most Promising Drugs of 2015

    Mar 23, 2015, 00:00 AM by Michael Croft
    PHILADELPHIA, PA, UNITED STATES - Mar 23, 2015 - The Intellectual Property and Science business of Thomson Reuters, the world’s leader in intelligent information for businesses and professionals, today released the 2015 edition of its annual Drugs to Watch report
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  • New Online Tool Creates Guide RNAs for CRISPR Gene Editing

    Mar 20, 2015, 11:30 AM by Michael Croft
    Bio-IT World | Horizon Discovery, a Cambridge, UK-based research supply company with a focus on gene editing experiments, has launched a free online tool to design guide RNA for CRISPR experiments.
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  • CRISPR in the Germline

    Mar 20, 2015, 10:25 AM by Michael Croft
    Bio-IT World News Brief | There is a renewed urgency to public conversations about the ethics of genome editing, thanks to the emergence of CRISPR, a gene engineering technology so effective and easy to use that scientists are racing to keep up with its potential applications.
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  • Albumin Fusion Protein Production Services Are Available in Creative BioMart Now

    Mar 20, 2015, 00:00 AM by Michael Croft
    SHIRLEY, NY, UNITED STATES - Mar 20, 2015 - March 20, 2015-Creative BioMart, a leading supplier for reagents in the biotechnology field, today has added novel Albumin Fusion Protein Production Services to its protein expression services
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  • Hsp90 Focused Library from OTAVA

    Mar 20, 2015, 00:00 AM by Michael Croft
    - Mar 20, 2015 - Nowadays, a number of highly potent and pharmaceutically improved heat shock protein 90 (Hsp90) inhibitors are undergoing clinical trials
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  • The Right Drug the First Time

    Mar 19, 2015, 11:10 AM by Michael Croft
    Bio-IT World | Scientists in the growing field of pharmacogenetics believe that new DNA tests can protect patients from adverse drug responses and ineffective prescriptions. Yet it's been an uphill battle to convince payers, medical centers, and clinicians to embrace these tests in mainstream medicine.
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