Nov 18, 2014, 00:00 AM by Michael Croft

Pharmalot | Later today, the Tufts Center for the Study of Drug Development will release a report that will take yet another stab at determining the true cost of developing a medicine. In the meantime, Ed Silverman is running a poll.

Nov 18, 2014, 00:00 AM by Michael Croft

MUNICH, GERMANY - Nov 18, 2014 - Major opportunities are on the horizon for personalized medicine and clinical cancer research and treatment, according to Definiens, the global leader in Tissue Phenomics® for oncology diagnostics

Nov 17, 2014, 15:00 PM by Michael Croft

Computerworld | The latest Top500 list is out, but only one new system made it into the top ten. The Chinese Tiahne-2 has kept its number on position for the fourth time, even though it has not changed its computing power.

Nov 17, 2014, 11:00 AM by Michael Croft

Bio-IT World Roundup | The results of the IMPROVE-IT trial were announced today, a seven-year study looking at whether Merck's Vytorin and Zetia pills actually prevent heart attack. The answer: yes. At least some.

Nov 17, 2014, 00:00 AM by Michael Croft

NEW YORK, NY, UNITED STATES OF AMERICA - Nov 17, 2014 -  Medidata (NASDAQ: MDSO), the leading global provider of cloud-based solutions for clinical research in life sciences, today announced the completion of a method development project conducted in partnership with GlaxoSmithKline plc (GSK) to evaluate the impact of unifying mobile health (mHealth) devices with cloud-based technologies in a clinical trial setting

Nov 14, 2014, 12:00 PM by Michael Croft

Nature | Oak Ridge National Laboratory (ORNL) in Tennessee and the Lawrence Livermore National Laboratory in California announced today their plans to upgrade to a next-generation IBM supercomputer that will run at 150 petaflops.

Nov 14, 2014, 08:00 AM by Michael Croft

Mashable | Google has raised the stakes in the A.M. Turing Award, offering $1 million. The annual awards recognize "major contributions of lasting importance to computing," and until now have included a cash prize of $250,000.

Nov 14, 2014, 00:00 AM by Michael Croft

VAUGHAN, ON - Nov 14, 2014 - 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1, 11beta-HSD1) is an NADPH-dependent enzyme, which catalyses conversion of inactive glucocorticoids 11-dehydrocorticosterone and cortisone to active corticosterone and cortisol and vice versa

Nov 13, 2014, 08:00 AM by Michael Croft

Nov 12, 2014, 15:00 PM by Michael Croft

Bio-IT World | A sequencing study published tomorrow in the New England Journal of Medicine has further characterized the activity of the Niemann-Pick C1-like 1 protein (NPC1L1). Carriers of inactivating mutations of NPC1L1 were found to have a 53% lower risk of coronary heart disease and an average LDL cholesterol level 12 mg per deciliter lower than that of noncarriers.

Nov 12, 2014, 00:00 AM by Michael Croft

SALT LAKE CITY AND ST LOUIS, MO, US - Nov 12, 2014 - ST LOUIS and SALT LAKE CITY (Nov. 12, 2014) – ARUP Laboratories and PierianDx announced today a partnership that will result in faster and more efficient diagnostic genetic testing for thousands of patients across the U

Nov 10, 2014, 13:40 PM by Michael Croft

Bio-IT World News Brief | Evan Eichler of the University of Washington and colleagues have published a paper in Nature detailing a new whole human genome assembly, using the long-reading SMRT sequencing technology of Pacific Biosciences.

Nov 10, 2014, 11:10 AM by Michael Croft

Bio-IT World | Emmanuelle Charpentier and Jennifer Doudna, co-discoverers of the CRISPR-Cas9 mechanism that has swiftly become a groundbreaking tool in genetic engineering, are among this year's winners of the $3 million Breakthrough Prizes in the Life Sciences awarded by a coalition of tech billionaires.

Nov 7, 2014, 10:05 AM by Michael Croft

Bio-IT World | As a new crop of patient-facing genomic health companies adjusts to cheaper DNA data and more intense FDA oversight, Jorge Velarde, a former Illumina executive and the new CEO of BaseHealth, tells Bio-IT World what we can expect from this second wave of interest in our genomes' influence on health.

Nov 7, 2014, 00:00 AM by Michael Croft

- Nov 7, 2014 - CREB-binding protein (CREBBP, CBP) is a transcriptional coactivator of a broad range of transcription factors

Nov 6, 2014, 15:00 PM by Michael Croft

Technology Review | Google Genomics says it is storing at least 3,500 genomes at the rate of $25 per genome per year. The analytics cost extra.

Nov 6, 2014, 15:00 PM by Michael Croft

ReadWrite | One acquisition in the Big Data space could change everything, one analyst predicts, pointing out that if Oracle or Cisco were to snap up one of the Big Data start-ups the collateral damage would be severe.

Nov 6, 2014, 10:05 AM by Michael Croft

BetaBoston | Foundation Medicine, the largest and most visible provider of broad genetic tests for personalized cancer therapy, announced this week that Google will pay for its tests for anyone covered under Google health plans.

Nov 6, 2014, 00:00 AM by Michael Croft

THE WOODLANDS, TX, UNITED STATES - Nov 6, 2014 - MolecularHealth announced today that Medical Director Gabriel Bien-Willner, M.D., Ph.D., will speak at this year’s Personalized Medicine Conference

Nov 5, 2014, 09:05 AM by Michael Croft

Bio-IT World News Brief | AstraZeneca announced that it has acquired Definiens, a diagnostics company specializing in image analysis software, as part of a strategy to refine its immuno-oncology programs.