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Aspera Speeds Data in Amazon Cloud
Mar 15, 2012, 04:55 AM by Michael CroftMarch 15, 2012 | SAN DIEGO—The directory of Aspera’s approximately 1,400 clients reads like the Fortune 500 list. These organizations use Aspera’s proprietary software to speed up the transfer of large volumes of data, which is significantly impacted by latency and packet loss. “We’ve solved the fundamental problem of moving big data over public and private networks,” Aspera’s Daniel Kumi, director of sales and business development, told an audience at CHI’s XGen Congress last week.Full story -
Dr. Watson: IBM's Clinical Genomics Platform
Mar 15, 2012, 03:45 AM by Michael CroftSmart Planet | IBM has launched an analytics platform using some of the natural language processing of Watson for use in a health care setting.Full story -
Clinical Genomics for Leukemia Patients
Mar 15, 2012, 02:35 AM by Michael CroftReuters | Two studies published in the New England Journal of Medicine explore genetic profiling's role in the treatment of AML, acute mylogenous leukemia.Full story -
VCF and the Genome Analysis Toolbox
Mar 14, 2012, 05:15 AM by Michael CroftBio-IT World | Inside the Box | We tend to take the extraordinary for granted. Roughly ten years ago we saw the first human genome sequence at a cost of roughly $3 billion. Now a person could have their genome sequenced in a few days for a few thousand dollars, turn around, and in a few more days compute how their sequence differs from any public sequence. This analysis might cost you just a few more dollars to rent the server. Let’s consider how one version of the bioinformatic part of this exercise might work.Full story -
Broad's Heng Li Wins 2012 Benjamin Franklin Award
Mar 14, 2012, 03:20 AM by Michael CroftFull storyBio-IT World | Heng Li, a research scientist at the Broad Institute, is the winner of the 2012 Benjamin Franklin Award for Open Access in the Life Sciences. Li made essential contributions to the next generation sequencing (NGS) field with tools like SAMtools, BWA, MAQ, TreeSoft and TreeFam.
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Data Rich, but Insight Poor
Mar 14, 2012, 02:45 AM by Michael CroftHuffington Post | After yet another story about genomics’ impending explosion, one editor wonders why a “data rich” environment is lauded as the answer.Full story -
Drug Company Helps Shift Treatment Focus
Mar 14, 2012, 01:35 AM by Michael CroftXconomy | Seattle Genetics’ first product, Adcetris, was approved by FDA in August. The drug targets a receptor in Hodgkin’s disease and anaplastic large cell lymphoma. The drug works, but the target market is small. So Seattle Genetics is launching a study to find other cancers with the same receptor.Full story -
Wisconsin Stem Cell Group Wins Cycle Computing $10,000 Challenge
Mar 13, 2012, 07:00 AM by Michael CroftBio-IT World | Victor Ruotti, a computational biologist at the Morgridge Institute for Research, University of Wisconsin-Madison, has won the 2012 CycleCloud BigScience Challenge. Ruotti will be awarded $10,000 of computation time on the Amazon cloud—the equivalent of eight hours on a 30,000-core cluster.Full story -
Phylo Proves Gamers' Advantage
Mar 13, 2012, 03:10 AM by Michael CroftNature | Gamers are proving themselves adept and untangling genomic problems once again. Data from the online game Phylo has helped tackle a problem in comparative genomics and was published in PLoS One.Full story -
Reflections on Ten Years of Bio-IT
Mar 12, 2012, 02:10 AM by Michael CroftBio-IT World | To mark the 10th anniversary of Bio-IT World’s launch in March 2002, we have invited dozens of prominent scientists and bio-IT professionals, many of whom have featured in our pages and our conferences over the years, to reflect on the most transformative changes they have witnessed over the past decade.Full story -
Bayer Drug Approvals and Growth in Asia Pacific
Mar 9, 2012, 02:20 AM by Michael CroftBio-IT World | SINGAPORE--Bayer’s focus in Asia Pacific has continued to grow in the last year, with the company experiencing 9.4% growth across Asia in 2011. Singapore, Vietnam, and Pakistan each enjoyed more than 26% growth in 2011, while markets in Malaysia and Indonesia grew by 14% and 13% respectively.Full story -
Progress and Problems in Clinical Genomics Sequencing at XGen Congress
Mar 8, 2012, 05:55 AM by Michael CroftBio-IT World | SAN DIEGO—Two leaders in the clinical application of whole genome sequencing offered further signs of progress in a pair of keynote talks at the 2012 XGen Congress. Rick Wilson, director of The Genome Institute (TGI) at Washington University, St Louis, and Elizabeth Worthey, bioinformatician at the Medical College of Wisconsin (MCW), shared new findings on the sequencing of cancer and pediatric cases. Although encouraging, Worthey in particular expressed some strong cautionary notes that are hampering current efforts in ending diagnostic odysseys.Full story -
Mutation Variability Across Single Tumors
Mar 8, 2012, 02:25 AM by Michael CroftBloomberg | A study published today in the New England Journal of Medicine shows that mutations in different parts of the same tumor can vary wildly. A single biopsy, then, may not give doctors enough information to identify mutations that should be targeted by drugs.Full story -
Computer-Aided Treatment Plans
Mar 8, 2012, 00:10 AM by Michael CroftXconomy | MolecularHealth has released a decision-support software platform for oncologists. The platform takes all the information a doctor has--including a patient's entire genome if it's been sequenced--and scans the available data and the medical literature and gives the oncologist a ranked list of treatment options.Full story -
Pharma's Missing Innovation
Mar 7, 2012, 03:45 AM by Michael CroftAtlantic | Sanofi CEO said the pharma is reducing its internal research capacity not because it's cheaper (though it is) but to take advantage of the best ideas in science.Full story -
Five Reasons Illumina Should Stay Independent
Mar 6, 2012, 03:00 AM by Michael CroftXconomy | The Illumina-Roche acquisition dance continues and Luke Timmerman says that if the low-ball takeover happens, it would be, "bad for Illumina shareholders, bad for the genetic tools industry, bad for science..."Full story -
Generic Drug Debates
Mar 6, 2012, 00:20 AM by Michael CroftHuffington Post | A tenent of Obama's health care plan was cheaper generic drug options, but that's proving easier said than done. Approving biosimilars is a complex and drawn-out process.Full story -
CDC Budget Cuts Could Put Agency at Risk
Mar 5, 2012, 00:30 AM by Michael CroftNature | President Obama's cuts in CDC funding could spell disaster for the agency. The CDC has had its overall budget cut by 20% since 2010. Some of the cuts are meant to be made up by other government spending, but some of those sources' budgets are not yet approved by Congress.Full story -
The Myth of the Low-Hanging Fruit
Mar 5, 2012, 00:10 AM by Michael CroftForbes | The "low-hanging fruit" that fueled biotech and pharma in the past is a myth, says John LaMattina. R&D isn't emerging from a golden age of discovery; research has always been hard and the blockbusters of yesterday came at the expense of "spectacular failures."Full story -
The Statin-Diabetes Link
Mar 5, 2012, 00:05 AM by Michael CroftNew York Times | The Food and Drug Administration warned last week that statins could be causing a sharp increase in Type 2 diabetes and contributing to memory loss among users.Full story