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IBM Provides NIH Free Chemical Compound Database
Dec 8, 2011, 01:45 AM by Michael CroftFull storyBio-IT World | IBM, Bristol-Myers Squibb, DuPont, and Pfizer are providing the National Institutes of Health with a database of more than 2.4 million chemical compounds extracted from about 4.7 million patents and 11 million biomedical journal abstracts from 1976 to 2000. The chemical data should help researchers more easily visualize important relationships among chemical compounds to aid in drug discovery and support advanced cancer research.
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Helpful, Harmful, Confusing: Direct-to-Consumer Genomics
Dec 8, 2011, 01:20 AM by Michael CroftJAMA | James Evans, professor of genetics at the University of North Carolina, is concerned about exome sequencing services like those offered by 23andMe. In a commentary published yesterday in JAMA, Evans and UNC co-author Jonathan Berg argue that whole genome and whole exome sequencing technology “will routinely uncover both trivial and important medical results, both welcome and unwelcome."Full story -
Genomic Health Test Spares Women Unncessary Radiation
Dec 7, 2011, 11:25 AM by Michael CroftUSA TODAY | According to results presented at the San Antonio Breast Cancer Symposium, a new 12-gene test from Genomic Health could spare thousands of women diagnosed with ductal carcinoma in situ (DCIS) annually by predicting which cases are most likely to be aggressive — requiring both surgery and radiation — versus surgery alone.Full story -
NHGRI Funding Plan Includes Clinical Sequencing, Software and Disease Research
Dec 6, 2011, 11:40 AM by Michael CroftBio-IT World | The NHGRI has announced the latest iteration of its flagship genome sequencing program -- worth $416 million over four years -- that features initiatives in the study of rare inherited diseases, software development and accelerates the use of genome sequence information in the clinical arena.Full story -
Crescendo Bioscience’s Aspirations
Dec 5, 2011, 07:30 AM by Michael CroftFull storyBio-IT World | The Russell Transcript | The rise of personalized medicine—however broadly or narrowly we define it—has been stymied in part by a lack of effective biomarkers. Cancer is perhaps an early and growing exception. The trend to profile a specific patient’s tumor for markers to help physicians pick the best therapeutic regime is a good example of the growing sophistication of biomarkers and their long-term potential as the cost of performing such tests declines.
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H3 Biomedicine: Health, Hope and Heaps of Japanese Funding
Dec 2, 2011, 09:15 AM by Michael CroftFull storyBio-IT World | The dedication of oncology drug company H3 Biomedicine's sparkling new laboratories in the heart of Kendall Square is more notable for the liberating and possibly unique funding from Japan drug maker Eisai Co., which is provding $200 million over ten years to allow the company to focus on the science of drug discovery and development.
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Why It's Open Science for Allen Brain Institute
Dec 2, 2011, 03:20 AM by Michael CroftWall Street Journal | The Allen Institute for Brain Science chose to make all of its data freely available online in an effort to accelerate research on brain diseases. The institute decided in 2002 that the best way to propel neuroscience forward would be to build a molecular-level, three-dimensional map of the mouse brain and give it away.Full story -
How Data Handling Could Stall Genomic Medicine
Dec 1, 2011, 03:25 AM by Michael CroftNew York Times | BGI's sequencers are now producing the equivalent of 2,000 human genomes a day, and shipping the results to customers via FedEx. Data handling is now the major bottleneck of the genomics industry and it could delay the day when DNA sequencing is used in medicine.Full story -
Science in Thrall to FDA
Nov 30, 2011, 09:30 AM by Michael CroftBio-IT World | The Skeptical Outsider | Risk aversion is the inherent enemy of progress. In a free society we can each seek our own balance, accepting the consequences. But when entrenched interests are allowed to thwart attempts by innovators and entrepreneurs to challenge the status quo, we all pay the price. As America slides into malaise and decline, nowhere is this more evident than in our passive acceptance of the absolute power of the U.S. Food and Drug Administration—even in the face of certain death. It need not be so.Full story -
The British are Coming: Connecting People and Patients
Nov 29, 2011, 01:20 AM by Michael CroftBio-IT World | Why would a chemist who has worked for some of the leading bio-IT companies of the 15-20 years, including Celera Genomics, Applied Biosystems, D.E. Shaw Ventures and IBM, find himself working for the company formerly known as British Telecom? “I was just as surprised,” said Yury Rozenman, who is BT Global Services’ head of marketing strategy and solution development for life sciences.Full story -
Survey Says: Tool Up for Smarter Clinical Studies
Nov 28, 2011, 00:45 AM by Michael CroftFull storyBio-IT World | Separate industry surveys by information technology research and advisory firm Gartner and global software company ClearTrial make a strong case for clinical resource management tools in the cost-cutting arsenal of biopharmaceutical and medical device companies.
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Cycle Computing Announces BigScience Challenge Finalists
Nov 23, 2011, 00:05 AM by Michael CroftCompute Cycles Blog | Cycle Computing announced the finalists of the CycleCloud BigScience Challenge at Supercomputing 11. They will announce a grand prize winner who will recieve $12,5000 worth of computing time.Full story -
Washington University unveils 'GPS' cancer gene sequencing panel
Nov 22, 2011, 08:15 AM by Michael CroftWashington University | A new medical service called Genomics and Pathology Services at Washington University School of Medicine in St. Louis (GPS@WUSTL) plans to offer a new sequencing test for mutations in 28 cancer-associated genes, which can be ordered by physicians across the U.S. to simultaneously examine a group of genes likely to influence treatment of a patient’s tumor.Full story -
An Insider Perspective on PAREXEL
Nov 22, 2011, 02:40 AM by Michael CroftBio-IT World | Mark Goldberg, PAREXEL’s chief operating officer, recently sat down with Bio•IT World chief editor Kevin Davies to discuss the importance of convergence in Perceptive Informatics’ suite of eClinical offerings, and to share his insights on the future opportunities, trends, and challenges facing the industry.Full story -
Texas Congressman Seeks to Block FDA Regulating Genetic Tests
Nov 21, 2011, 09:40 AM by Michael CroftThe Hill | Letting the FDA regulate genetic tests would cripple innovation in a field with tremendous promise for patients and U.S. competitiveness, Rep. Michael Burgess (R-Texas) said last week at a policy forum co-sponsored by the American Clinical Laboratory Association.Full story -
Open Data and Patient Modeling in Europe
Nov 21, 2011, 09:15 AM by Michael CroftFull storyBio-IT World | HANNOVER, GERMANY—“The tools and library situation in bioinformatics is an open-source zoo,” said Misha Kapushesksy, functional genomics team leader with the European Bioinformatics Institute (EBI), during his presentation on the Gene Expression Atlas platform. If that’s so, attendees got quite a tour of menagerie at the third annual Bio-IT World Europe conference*, with much emphasis on open-source platforms and cloud deployments.
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Notes from the Floor: SC11
Nov 18, 2011, 04:30 AM by Michael CroftBio-IT World | This week’s Supercomputing 11 (SC11) conference in Seattle was full of news and product announcements across the industry, many of which featured companies active in life sciences. Here’s just a sampling of what caught Bio-IT World’s eye and ear.Full story -
Can Big Data Fix Healthcare?
Nov 17, 2011, 13:00 PM by Michael CroftForbes.com | "The era of Big Data in healthcare has arrived," says GNS Healthcare CEO and co-founder Colin Hill in his debut "Healthcare 2020" blog.Full story -
Perakslis, Mesirov and Leach Named Bio-IT World Expo 2012 Keynotes
Nov 17, 2011, 08:35 AM by Michael CroftFull storyBio-IT World | Bio-IT World has announced that Eric Perakslis (the newly appointed FDA CIO), Martin Leach (CIO, Broad Institute) and Jill Mesirov (chief informatics officer, Broad Institute) will be the featured keynote speakers at the 10th anniversary Bio-IT World Conference & Expo, which will be held in Boston on April 24-26, 2012.
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PerkinElmer Targets Holistic Data Solutions
Nov 17, 2011, 01:55 AM by Michael CroftFull storyBio-IT World | With its recent acquisitions of CambridgeSoft and Geospiza to name but two, PerkinElmer is signaling a new strategy that highlights data analysis and software as much as its traditional strengths in hardware and chemical analysis. Spearheading the new strategy is Dan Marshak, an accomplished cell biologist who has served as PerkinElmer’s chief scientific officer for five years. Marshak sat down with Bio•IT World chief editor Kevin Davies to discuss PerkinElmer’s evolving strategy from both business and scientific perspectives.