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A Turnaround for Toxicogenomics?
Nov 16, 2010, 04:05 AM by Michael CroftBio-IT World | With a 90% drug attrition rate in clinical trials due primarily to the high incidence of adverse effects, there is a huge financial incentive for drug companies to develop methods that will quickly eliminate toxic compounds from the drug pipelines.Full story -
Chinese Supercomputer Ranked Top in the World by Top500
Nov 16, 2010, 03:40 AM by Michael CroftFull storyInformationWeek | China bests the US in the most recent Top500 list of the fastest supercomputers in the world. China's Tianhe-1A system in Tianjin achieved 2.57 petaflops per second to earn first place.
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EMC Buys Isilon for $2.25 billion
Nov 16, 2010, 03:30 AM by Michael CroftFull storyBloomberg | EMC announced yesterday that it had purchased Isilon Systems for $2.25 billion, pushing it deeper into the external-storage market.
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Complete Genomics' IPO Less Than Expected
Nov 12, 2010, 01:50 AM by Michael CroftFull storyXconomy | Complete Genomics' IPO this week came in lower than they had expected. Originally predicting $12-$14 per share, the initial prices was $9 per share and stock fell 11% the first day of trading, closing at $8.03.
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Gene Mutation Determines Patient Response to AML
Nov 12, 2010, 00:45 AM by Michael CroftFull storyMed Page Today | Findings published in the New England Journal of Medicine pinpoint a gene with multiple mutations that seems to determine patient response to acute myeloid leukemia (AML).
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Futreal's Deeper and Wider Approach to Cancer Genomes
Nov 10, 2010, 08:40 AM by Michael CroftFull storyBio-IT World | Cancer researcher Andy Futreal at the Wellcome Trust Sanger Institute believes there is plenty of cause for optimism when it comes to sequencing cancer genomes. Speaking at the Frontiers in Cancer Science 2010 meeting in Singapore, Futreal catalogued the cancer advances over the past ten years of genome sequencing, and proposed future directions for the field.
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454 Enters Partnership for Sequencing Semiconductor
Nov 4, 2010, 04:55 AM by Michael CroftFull storyBio-IT World | DNA Electronics and 454 Life Sciences have entered a partnership to develop a low-cost, high-throughput, long read, high density DNA sequencing system. The technology is expected to build on 454's current pyrosequencing-based platform.
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Biomatters Launches Next Gen Analysis Server
Nov 3, 2010, 12:45 PM by Michael CroftFull storyBio-IT World | Biomatters launched their newest software package yesterday, Geneious Server, to analyze next-generation sequencing data, and it's already found customers in Centers for Disease Control and Prevention (CDC) in Atlanta and Walter Reed Army Institute of Research in Maryland.
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Lander’s Lessons Ten Years after the Human Genome Project
Nov 3, 2010, 02:00 AM by Michael CroftFull storyBio-IT World | If anyone was capable of distilling the lessons learned in the ten years since the first draft of the Human Genome Project in 2000, it was Broad Institute director Eric Lander in the opening address at the annual American Society of Human Genetics (ASHG) convention in Washington, D.C.
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Databases Down Under
Nov 2, 2010, 05:15 AM by Michael CroftFull storyBio-IT World | BRISBANE—At TRX10, Translational Research Excellence, held last month in Brisbane, amid a wide-ranging program covering everything from stem cell models to commercializing academic innovations, translational approaches to cancer and central nervous system disease to trial design, discussion turned to repositories for genetic and clinical data. Researchers encouraged one another to share raw data, analyses, and clinical findings to further research and enable advances in medicine.
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IPOs for the Next Generation
Nov 1, 2010, 02:25 AM by Michael CroftFull storyXconomy & Wall Street Journal Blog | Last week Pacific Biosciences raised $200 million through its IPO, a number in the middle of its expected range. The IPO was also good news for Complete Genomics, which released an amended IPO prospectus raising its self valuation to $12 to $14/share.
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Novartis Investing, Expanding in Cambridge
Oct 28, 2010, 11:35 AM by Michael CroftFull storyBoston Herald | Novartis is planning to add 300 new jobs and invest $600 million over the next five years to expand its research campus adjacent to the former Necco candy factory in Cambridge, Mass.
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The IP Picture for iPS Cells
Oct 28, 2010, 01:00 AM by Michael CroftFull storyBio-IT World Expert Commentary | An exciting recent advance in medicine has been the generation of induced pluripotent stem (iPS) cells which are derived from somatic cells, rather than embryos, through a process of “de-differentiation.” But the advance raises important intellectual property and patent questions.
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Sequence, Drugs and Rock n’ Roll: How Ozzy Osbourne Took a Bite Out Of His Genome
Oct 27, 2010, 14:30 PM by Michael CroftFull storyBio-IT World | Following the revelation in The Sunday Times that rock music legend Ozzy Osbourne has had his genome sequenced, Bio-IT World talks to the people at Cofactor Genomics, LIfe Technologies, and Knome who deciphered the Prince of Darkness' DNA.
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1000 Genomes Project Completes its First Map of Human Genetic Variation
Oct 27, 2010, 13:35 PM by Michael CroftFull storyThe Guardian | Researchers have unveiled results from the pilot phase of the 1000 Genome Project, which aims to sequence the genetic code of 2,500 people. It is the most complete inventory yet of the millions of variations between people's DNA.
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Former ImClone CEO Makes $100 Million Acquisition
Oct 26, 2010, 03:35 AM by Michael CroftFull storyReuters | Sam Waksal, former ImClone CEO, has announced that his drug company Kadmon Pharmaceuticals has bought Three Rivers Pharmaceuticals and its treatments for hepatitis C.
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Free Amazon Micro Instance
Oct 25, 2010, 04:35 AM by Michael CroftFull storyPC World | Amazon is offering free access to EC2 starting on Nov 1. The offer includes one year of access to a "micro instance", 750 hours' use per month.
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Placing the Target User First in Clinical Trial Technology
Oct 25, 2010, 04:30 AM by Michael CroftFull storyBio-IT World | Expert Commentary | In the past decade, clinical trial technology has undergone a series of evolutions in its design, capability and deployment. From the early days of remote data capture to full-suite clinical trial management solutions, this evolution is redefining clinical research. Yet despite its dominance, clinical research technology has suffered from significant resistance at the study site level, which can be traced to a deficit in one basic element: user-centered design.
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Chinese Chips
Oct 22, 2010, 00:00 AM by Michael CroftFull storyTechnology Review | Three new chips out of China might lead to a Chinese supercomputer that can compete on the international scale. The three newest members of the Godson processor family are a one-gigahertz, eight-core Godson 3B; the most powerful 16-core Godson 3C; and the one-gigahertz Godson 2H.
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2011 Bio-IT World Best Practices Open
Oct 18, 2010, 04:45 AM by Michael CroftFull storyBio-IT World | The 2011 Bio-IT World Best Practices competition has released its call for entries. Since 2003, Bio-IT World's Best Practices competition has been recognizing outstanding examples of technology and strategic innovation initiatives across the drug discovery enterprise. The deadline for entry is January 14, 2011, and the early bird deadline is December 19, 2010.


