• Exploring the Changing Approach to Drug Safety

    Bio-IT World | Pharmacovigilance plays a critical role in drug safety. Pharmaceutical companies monitor newly licensed drugs, evaluate previously unreported adverse reactions, and balance drug effectiveness. We are evolving from manual pharmacovigilance to an era of precision pharmacovigilance, where a personalized approach to drug safety helps maximize the reach of new drugs and minimize adverse events.

    Feb 17, 2023

  • Natural Language Processing Designs Original Proteins From Scratch

    Bio-IT World | Using a natural language processing program developed by Salesforce Research, scientists have engineered artificial enzymes that look and fold just like natural proteins and function just as well. The artificial intelligence tool, called ProGen, allows information from the evolutionary record of multiple protein families to generate new enzymes that could prove therapeutically useful.

    Feb 16, 2023

  • New Zinc-Finger Technology Makes For Faster, Better Genetic Editing

    Bio-IT World | CRISPR-based approaches that rely on the enzyme Cas9 to cut DNA at precise locations has been the darling of genetics research over the past few years. The revolutionary gene-editing system can also produce a lot of off-target activity. And when delivered via adeno-associated virus vectors, Cas9 occupies so much space that little room is left for any other therapeutic cargo that might be needed.

    Feb 14, 2023

  • Bioassays Have An Integration Problem: Collaboration Will Be Key To Making Them FAIR

    Bio-IT World | Whilst life science companies have come to recognize data as their greatest asset, it is also their greatest challenge. Much of data is siloed in different formats and locations, making it difficult to discover, query, and share—rendering data essentially unusable. FAIR data must be rolled out across the entire industry if companies want to accelerate R&D and enable scientific queries to be answered more rapidly.

    Feb 10, 2023