• The Women’s Health Gap: 5 Cautionary Tales of Clinical Blunders

    Bio-IT World | Progress on women’s health, which was only truly recognized at the federal level when the Food and Drug Administration (FDA) asked for the inclusion of women in clinical trials in 1993, encountered a large obstacle earlier this year when the White House cut off a major funding initiative established by previous administrations intended to right the harms from decades of largely failing to include women in medical research. The move marks a succession of blind spot moments in the history of human research that have had damaging consequences for women.

    Nov 19, 2025

  • ASTRA Consortium Unites Asia-Pacific Scientists to Build Pan-Cancer Spatial Atlas

    Bio-IT World | Last week, The Garvan Institute of Medical Research in Australia, the University of Tokyo in Japan, and 10x Genomics announced an initiative to create a comprehensive pan-cancer spatial atlas. The Asia-Pacific Spatial Translational Research Alliance (ASTRA), a consortium that fosters collaboration in spatial research across the Asia-Pacific region, will use 10x Genomics’ Xenium spatial platform to map how cancer and immune cells communicate across 2,000 tumor samples.

    Nov 18, 2025

  • Why Are We Focused on Simulation-based Methods for Predicting Binding Affinity?

    Bio-IT World | Early computational drug discovery relies on accurate predictions of binding affinity. If we can accurately predict the affinity of molecule designs, we can dramatically reduce the number of compounds that we need to synthesize and test when optimizing new drug candidates.

    Nov 14, 2025

  • Why Overlooking Female Biology Still Impairs Drug Development

    Bio-IT World | Though gender equity efforts in research have made strides, progress has plateaued. Roughly two-thirds of pivotal clinical trials leading to the U.S. Food and Drug Administration (FDA) drug approvals now include women at rates proportional to their disease burden, but the problem is fundamental issues in not considering female biology.

    Nov 12, 2025

  • United Genetic, Epigenetic Readouts From The Same DNA Molecule

    Bio-IT World | Watchmaker Genomics has launched TAPS+, a next-generation technology that unites genetic and epigenetic readouts from the same DNA molecule. By capturing multiple biological dimensions in a single assay, TAPS+ delivers a richer, more comprehensive view of tumor biology.

    Nov 11, 2025

  • Revolutionizing ADC Manufacturing: How Single-Use Technologies Are Reshaping Biopharma Efficiency and Safety

    Bio-IT World | Antibody-drug conjugates (ADCs) are among the most promising and complex therapeutics in modern oncology. The global ADC market is growing at an extraordinary pace. Yet, this promise comes with complexity. Multi-step conjugations, long processing times, highly potent raw materials, and stringent quality requirements pose significant manufacturing challenges.

    Nov 6, 2025

  • DNA Nanotech Brings Precision Drug Monitoring to At-Home Use

    Bio-IT World | For millions of patients prescribed drugs with a narrow therapeutic window, safe dosing depends on therapeutic drug monitoring. But outside of hospital labs equipped with specialized machines and trained staff, monitoring drug concentrations in real time has been largely out of reach. DNA nanotechnology may hold the key to bringing this critical capability to the point of care—and even into patients’ homes.

    Nov 5, 2025