• Has Validation In An Agile Software Development Environment Come Of Age?

    Bio-IT World Contributed Commentary | Today it is accepted that agile software development can work well within a formal project and most software vendors supplying the pharmaceutical industry have an agile aspect to their Software Development Life Cycle (SDLC).

    Dec 12, 2019
  • Precision Medicine: Setting a Strong Foundation to Accelerate Progress

    Bio-IT World Contributed Commentary | Precision medicine depends on data—more specifically, on our ability to analyze and act on it from the bench to the bedside and back again. And, we’ve long understood that our ability to direct data—both structured and unstructured—when and where it’s most needed is foundational to advancing and unlocking the promise of precision medicine.

    Dec 11, 2019
  • Clockwork: Scientists Tinker with the Inner Workings of Circadian Rhythm

    Bio-IT World | The human clock is increasingly being thrown off-kilter by our modern lifestyles—TVs in bedrooms, electronic books in bed, smartphones sitting on nightstands. These types of technologies, and other disruptors like jet lag or third shift work, can wreak havoc on our bodily rhythm and, along with it, bodily processes. Circadian dysfunction has been linked to a higher risk of health issues like obesity, diabetes, and certain forms of cancer. Enter circadian rhythm research.

    Dec 9, 2019
  • Asia-wide Genome Mapping Project Reveals Insights Into Asian Ancestry, Genetic Diversity

    Bio-IT World News Brief | In their first study reported in Nature this week, the GenomeAsia 100K consortium analyzed the genomes of 1,739 people, which represents the widest coverage of genetic diversity in Asia to date.

    Dec 6, 2019
  • To Advance Polygenic Risk Scores, Large Studies Need Better Genotyping Tools

    Bio-IT World Contributed Commentary | A decade ago, the concept of a polygenic risk score had not even been cited in a genomics publication. Today, it’s almost impossible to pick up a human genetics journal or attend a conference without hearing about these new biomarkers.

    Dec 5, 2019
  • The Nose Knows: Developing Artificial Intelligence Sniffers

    Bio-IT World | When you think of artificial intelligence, what comes to mind? A computer brain? Computer vision? Auditory language processing? What about smell? It’s an area of research IBM is busy exploring.

    Dec 4, 2019
  • Benchling: Enabling the Next Generation of Data and Workflow Tracking

    Bio-IT World Benchling’s value proposition is easy to see. For researchers—whether in an academic lab, small biotech, or big pharma—keeping track of research using paper lab notebooks, email, and spreadsheets is cumbersome and inefficient. But the challenges to science are much bigger than just misplaced notes or forgotten results. The real value, says Saji Wickramasekara, comes from enabling a new level of collaboration and data provenance.

    Dec 2, 2019
  • HudsonAlpha, Vanderbilt, Thermo Scientific, and More: News From November 2019

    Bio-IT World | November featured exciting new, products, and partnerships from around the bio-IT community from innovating companies, organizations, and universities, including HudsonAlpha, Vanderbilt, Thermo Scientific, and more.

    Nov 27, 2019
  • Explosion Of Interest In Organ-On-A-Chip Technology

    Bio-IT World | Organ-on-a-chip models were practically nonexistent a decade ago, but significant advances are now being made every few months.

    Nov 25, 2019
  • Follow The Money: Investments and Funding Rounds for November

    Bio-IT World | Some of the latest funding updates from across life sciences, clinical trials, the diagnostics industries.

    Nov 22, 2019
  • Hesperos: A CRO For Body-On-A-Chip Enthusiasts

    Bio-IT World | Operationally, Hesperos works much like a contract research organization that delivers study results back to sponsoring companies, with its specialty being integration assistance to drug developers interested in using a multiorgan model for their preclinical efficacy and toxicity studies.

    Nov 22, 2019
  • Organs On Chips Will Make Drugs Safer—And More Precise

    Bio-IT World | The emergence of organ-on-a-chip systems to expedite drug discovery and toxicology studies is a process more than three decades in the making.

    Nov 21, 2019
  • Will Organ-On-A-Chip Models Be Viable Alternatives to Animal Testing?

    Bio-IT World | A new testing technology is of great interest to pharmaceutical companies looking to better understand the effects of medicines—especially the unintended consequences of their administration—and will facilitate study of not only toxicity, but also the mechanism by which drugs work and the timing of their delivery and physiological response.

    Nov 20, 2019
  • TOP500 Supercomputers List Announced

    TOP500 | The 54th edition of the TOP500 saw China and the US maintaining their dominance of the list, albeit in different categories.

    Nov 18, 2019
  • Reducing Wasted Life Science Research By Using Factorial Experiments

    Bio-IT World Contributed Commentary | To combat the waste of life science research, Sridhar Iyengar advocates building comprehensive lab monitoring and information systems that, using "AI", can "correlate fluctuations in many different variables" to deviations in observed results. There is, however, another completely different approach to tease out from the "myriad factors": factorial experimentation, in particular, 2-level screening experiments.

    Nov 18, 2019
  • Oxford Nanopore Develops Pore-C, Couples Chromatin Conformation Capture With Long Read Tech

    Bio-IT World News Brief | Last week Weill Cornell Medicine and Oxford Nanopore published a pre-print describing Pore-C, a new nanopore sequencing technique which couples chromatin conformation capture with Oxford Nanopore Technologies long reads to directly sequence multi-way chromatin contacts without amplification.

    Nov 14, 2019
  • Tumor Organoids For High-Throughput Drug Screening

    Bio-IT World | Interest is growing among oncology researchers in using tumor organoids to mimic cancer characteristics and drug responses in humans.

    Nov 13, 2019
  • OptraHEALTH, InformedDNA Partner To Expand Access To Genetics Experts

    Bio-IT World News Brief | OptraHEALTH and InformedDNA today announced that they will partner to offer access to InformedDNA’s board-certified genetic counselors through GeneFAX’s AI-enabled CounselorConnect platform.

    Nov 8, 2019
  • Healthy Gut Microbiome Reference Database Initiated

    Bio-IT World | A group of researchers describe an initial baseline healthy gut microbiome reference database and put forth a prototype reporting template. The goal behind the work is to map the healthy gut microbiome so that they and other researchers can use the data to develop disease-specific prediction models.

    Nov 6, 2019
  • Microsoft + The Jackson Laboratory Using AI To Fight Cancer

    The AI Blog | Jackson Lab is using AI from Project Hanover to find the most relevant cancer-related info from the thousands of research papers published each day.

    Oct 31, 2019