• Scientists Finally Finish The Quest For A Gapless Human Genome

    Bio-IT World | There was no escaping last week’s announcement that the final 8% of the human genome—the equivalent of an entire DNA chromosome—has been sequenced, filling a gap left nearly 20 years after the Human Genome Project declared victory. More than 100 researchers from around the world collaborated on the initiative and many of them, and the institutions they represent, have weighed in on the feat.

    Apr 7, 2022

  • AI Betting Agents Weigh In On Reproducibility Of Research Findings

    Bio-IT World | Penn State researchers have created synthetic “prediction markets” for speculating on the replicability of published studies with unparalleled accuracy. When betting on published social and behavioral science papers, about 90% of the time bot agents correctly “bought” papers that were eventually reproduced.

    Apr 5, 2022

  • Follow the Money: Single-Cell Analysis, Spatial Biology, Drug-Resistant Infection Treatments, 3D Genomics

    Bio-IT World | Funds raised for life science company investment, AI-powered single-cell analysis, spatial biology, ML-based discovery of new anti-infectives, and real-time supply chain operations analysis.

    Mar 31, 2022

  • New Illumina Accelerator Start-Ups, Blood Test for Liver Cancer, Several New Collaborations, Software Offerings, More

    Bio-IT World | A genomic network model is used to identify aurora kinase inhibitor-sensitive lung tumors, new Illumina Accelerator start-ups are announced, AI algorithms are being used to improve prostate cancer identification and treatment, and a blood-based DNA methylation test can detect liver cancer

    Mar 30, 2022

  • Digitization Vs. Digital Transformation at Alnylam

    Bio-IT World | Jim Bilotta found his home in orphan diseases early in his career, driven by both personal experience and the “unbelievable” impact on patients and their families. Today, as Chief Information Officer, head of IT, at Alnylam, he is still pursuing that impact. In the latest episode of Bio-IT World’s Trends from the Trenches podcast, Bilotta and Trends from the Trenches host, Stan Gloss, discuss digital transformation at Alnylam, and how Bilotta views the distinction between digitization and digital transformation.

    Mar 29, 2022

  • How Life Science Companies Can Harness the Predictive Value of Data to Drive Deeper Process Understanding

    Bio-IT World | As the biopharmaceutical industry begins to embrace advanced data collection and analysis tools, it finds itself facing a challenging question: How can drug manufacturers best harness all that data to improve capacity, reduce bottlenecks and cut costs? Establishing a strong digital backbone is the first critical step. From there, manufacturers need to figure out how to strengthen this digital backbone with technology that not only makes the data easily accessible, but also empowers manufacturers to analyze it and use it to make transformative predictions.

    Mar 28, 2022

  • Antibody That Opens Blood-Brain Barrier Might Also Ferry Lifesaving Drugs

    Bio-IT World | A future where single-chain nanobodies and biologically active proteins might voyage through the blood-brain barrier to treat neurological conditions—including Alzheimer’s disease and brain tumors—recently came closer into view with the discovery of an antibody that succeeded in temporarily opening and resealing the crucial filtering mechanism in mice.

    Mar 25, 2022

  • Blueprint For Radically Open, Citizen Science Approach To Aging Research

    Bio-IT World | Leonid Peshkin, Ph.D., is an unconventional man working at an Ivy League research university in a field he believes is rightfully viewed with “great skepticism” by mainstream biologists. The war on aging he is advancing puts to the test both interventions designed to extend healthspan (the period of life where one is healthy) and our understanding how the ravages of time get undone in the germline, an approach he likens to a Russian “Koschei” fairy tale where the secret to eternal health is in the egg.

    Mar 23, 2022

  • All of Us Program Releases 100K Diverse Whole Genomes

    Bio-IT World | Nearly 100,000 highly diverse whole genome sequences are now available through the National Institutes of Health's All of Us Research Program, the NIH announced today. About 50% of the data is from individuals who identify with racial or ethnic groups that have historically been underrepresented in research. This data will enable researchers to address yet unanswerable questions about health and disease, leading to new breakthroughs and advancing discoveries to reduce persistent health disparities.

    Mar 18, 2022