• ‘High-Risk, High-Reward’ Approach To Finding Alzheimer’s Disease Treatments

    Bio-IT World The quest to find new medicines for Alzheimer’s disease (AD) may finally make some headway, thanks to a Target Enablement to Accelerate Therapy Development for Alzheimer’s Disease (TREAT-AD) project that is taking a “high-risk, high-reward” approach to diversifying the drug development pipeline, according to Lara Mangravite, president of Sage Bionetworks. The Seattle-based nonprofit is partnered with Emory University and the Structural Genomics Consortium (SGC) on the initiative.

    Oct 19, 2020

  • FOXP3 Protein Inhibited, Blocking Factor D Protein May Prevent Inflammatory Response, App Crowdsources Drug Candidates: COVID-19 Updates

    Bio-IT World I Cloud-based tool, IDseq, allows tracking of emerging pathogens, scientist who discovered SARS captures detailed look of immune system response to COVID-19, SARS-CoV-2 may become endemic, ORF3B identified as viral factor that impairs immune response, age is an independent factor to virus susceptibility, group of 80 researchers warns against herd immunity approach, high dose favipiravir had significant effect on preventing and treating virus in hamster model, REGN-COV2 antibody ‘cocktail’ offers protection in pre-clinical trial on macaques. Plus: SARS-CoV antibodies effectively neutralize SARS-CoV-2 infection in cultured cells, international open access database aims to reduce duplication of ongoing COVID-19 research and more.

    Oct 15, 2020

  • Proving The Value Of Preventive Genomics

    Bio-IT World | The Bio-IT World Conference & Expo closed out with a plenary keynote presentation on preventive genomics by Robert Green, M.D., professor of medicine at Harvard Medical School and a physician-scientist who directs the G2P Research Program at Brigham and Women’s Hospital and the Broad Institute. Data-sharing difficulties were a recurring theme at this year’s conference but, as the COVID-19 Host Genetics Initiative has demonstrated, it is possible to combine genomic data to rapidly explore markers of disease, he says.

    Oct 14, 2020

  • Researcher-Driven Data Stewardship, Storage: Trends from the Trenches 2020

    Bio-IT World  | On its 10th anniversary, the annual Trends from the Trenches presentation from Chris Dagdigian, co-founder and principle consultant of BioTeam, and friends had lost none of its characteristic candor and punch—even in a virtual environment and even as Dagdigian successfully continued to limit his own speaking time.

    Oct 13, 2020

  • The Great Data Science Promise For COVID-19, Opioid Addiction

    Bio-IT World | The Bio-IT World Conference & Expo Virtual launched last week with an opening plenary keynote from Drs. Susan Gregurick, Associate Director for Data Science at NIH and Rebecca Baker, Director of the HEAL Initiative at NIH.

    Oct 11, 2020

  • Novel T Cell Subset, Nitric Oxide Effective Treatment Option, SoCal cases linked to New York: COVID-19 Updates

    Bio-IT World | MIT’s preprint reviewers debunk synthetic SARS-CoV-2 paper, genetic analysis of virus samples show most COVID-19 cases in Southern California early in the pandemic are linked to New York state via Europe, not directly from China, vaccines should not be affected by the dominant ‘G-strain’, severe cases of COVID-19 develop a novel T cell subset that can potentially kill B cells, and MS drug inhibits virus growth. Plus, NIH funds COVID-10 vaccine using bovine adenovirus.

    Oct 8, 2020

  • Bio-IT World Virtual: Gamifying Discovery, Human-in-the-Loop AI, New Data Commons Model

    Bio-IT World  Day two of the Bio-IT World Conference & Expo Virtual was highlighted by a plenary keynote on artificial intelligence (AI) and citizen science, a new data commons maturity model, guidance for FAIRifying data, augmented intelligence systems for biological data, and much more. 

    Oct 7, 2020