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George Church on 4D Omics, Natural Computing, and the BioWeatherMap
Bio-IT World | George Church opened the 20th Anniversary Bio-IT World Conference & Expo last night, speaking virtually to a packed room at Boston’s Hynes Convention Center while many more attendees tuned in online.
May 4, 2022
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Best of Show Awards Highlights New Products in Bio-IT
Bio-IT World | Bio-IT World is pleased to announce the competitors in the 2022 Best of Show competition with the Bio-IT World People’s Choice Award. Voting begins today.
May 3, 2022
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Follow the Money: Next-Gen Data-Driven Precision Medicine Development, DNA Synthesis Technology, More
Bio-IT World | Funding for programmable biology and chemistry in medicine development, DNA synthesis, immune-oncology cancer therapeutics, and more.
Apr 29, 2022
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Simultaneous CNV and Mutation Detection Method; AI-Enhanced Brain Imaging; More
Bio-IT World | AI and ML in clinical trials, metabolomics-based diagnostics, T-cell receptor engineering for cancer treatment, and cardiovascular disease drug development, new genomics efforts in Brazil, laboratory automation and risk management solutions, and more.
Apr 27, 2022
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James Cuff on Networks, Cloud, and the Problem that Drew Him Out of Retirement
Bio-IT World | James Cuff summarizes his career over the past 25 years or so, outlining where he’s seen updates in the space and which things have fundamentally stayed the same. He also shares about the problem that’s been bugging him for the past five years and the new company he’s joined that could fix it.
Apr 26, 2022
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PacBio Announces ML Methylation Calling, New Software, Consumables
Bio-IT World | Pacific Biosciences announced broad updates to its Sequel IIe and Sequel II Systems today including new capabilities in DNA methylation detection and workflow improvements promising a 50% decrease in NGS sequencing workflow and a 40% decrease in needed sample.
Apr 21, 2022
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Stanford: ‘Clinical Grade’ Long-Read Genome Sequencing Is Here
Bio-IT World | A Stanford team led by Euan Ashley, professor of medicine, genetics and biomedical data science, sequenced a patient’s genome in a snappy five hours and two minutes on a PromethION platform from Oxford Nanopore, an achievement ratified by the Genome in a Bottle Consortium of the National Institute of Science and Technology.
Apr 20, 2022
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Genomic Consortium Diversifies Data, Explores Genomics of Body Measurements
Bio-IT World | Genomic studies can benefit from leveraging diverse ancestries to make new discoveries about health and disease, write the authors of a new paper published in Human Genetics and Genomics Advances. They have launched a consortium focused on the genetics of Hispanic and Latin American populations.
Apr 19, 2022
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Whole Genome Covid-19 Sequencing Study Proves WGS Ready for Therapeutic Development
Bio-IT World | Last month an international team of researchers published whole genome sequencing results comparing thousands of individuals with critical Covid-19 to a control group, discovering and replicating 23 independent variants that significantly predispose an individual to critical Covid-19. The exercise yielded fruit for very large scale whole genome sequencing projects as well.
Apr 14, 2022
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Automated Data Cleaning and AI Pipelines for Increased Enterprise-Wide Adoption
Bio-IT World | The current data-rich era comes with a tremendous number of caveats. Large quantities of data are not necessarily high quality. Quality, in this case, can be used to describe the ease with which a user can obtain useful insights. Here we look at practices within a business that can maintain data integrity to prepare it for automated AI pipelines among other uses.
Apr 13, 2022
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The Right Questions: Bayer’s Approach to Data Challenges and COVID-19
Bio-IT World | The way Jeanne Kehren sees it, pharma either has data graveyards, or “We are building data lakes without thinking about getting a boat.” Neither option advances the life sciences mission. As SVP and CIO at Bayer, Kehren is working toward a new vision of how pharma uses data, what it means to ask the right question, and how the healthcare industry as a whole can serve patients. COVID-19, she said, has been both a magnifier of some of our challenges and an opportunity.
Apr 12, 2022
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Bio-IT World Names 2022 Innovative Practices Awards Winners
Bio-IT World | Bio-IT World today announced the 2022 Innovative Practices Awards winners. Four grand prize awards were granted to AstraZeneca, Guardant Health with IQVIA, Merck KGaA, Darmstadt, Germany, with Genedata, and Quantum Leap Healthcare Collaborative / University of California San Francisco with OpenClinica. The awards ceremony will be held during the plenary program on Tuesday, May 3, at the 2022 Bio-IT World Conference & Expo in Boston.
Apr 11, 2022
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Scientists Finally Finish The Quest For A Gapless Human Genome
Bio-IT World | There was no escaping last week’s announcement that the final 8% of the human genome—the equivalent of an entire DNA chromosome—has been sequenced, filling a gap left nearly 20 years after the Human Genome Project declared victory. More than 100 researchers from around the world collaborated on the initiative and many of them, and the institutions they represent, have weighed in on the feat.
Apr 7, 2022
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AI Betting Agents Weigh In On Reproducibility Of Research Findings
Bio-IT World | Penn State researchers have created synthetic “prediction markets” for speculating on the replicability of published studies with unparalleled accuracy. When betting on published social and behavioral science papers, about 90% of the time bot agents correctly “bought” papers that were eventually reproduced.
Apr 5, 2022
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Follow the Money: Single-Cell Analysis, Spatial Biology, Drug-Resistant Infection Treatments, 3D Genomics
Bio-IT World | Funds raised for life science company investment, AI-powered single-cell analysis, spatial biology, ML-based discovery of new anti-infectives, and real-time supply chain operations analysis.
Mar 31, 2022
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New Illumina Accelerator Start-Ups, Blood Test for Liver Cancer, Several New Collaborations, Software Offerings, More
Bio-IT World | A genomic network model is used to identify aurora kinase inhibitor-sensitive lung tumors, new Illumina Accelerator start-ups are announced, AI algorithms are being used to improve prostate cancer identification and treatment, and a blood-based DNA methylation test can detect liver cancer
Mar 30, 2022
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Digitization Vs. Digital Transformation at Alnylam
Bio-IT World | Jim Bilotta found his home in orphan diseases early in his career, driven by both personal experience and the “unbelievable” impact on patients and their families. Today, as Chief Information Officer, head of IT, at Alnylam, he is still pursuing that impact. In the latest episode of Bio-IT World’s Trends from the Trenches podcast, Bilotta and Trends from the Trenches host, Stan Gloss, discuss digital transformation at Alnylam, and how Bilotta views the distinction between digitization and digital transformation.
Mar 29, 2022
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How Life Science Companies Can Harness the Predictive Value of Data to Drive Deeper Process Understanding
Bio-IT World | As the biopharmaceutical industry begins to embrace advanced data collection and analysis tools, it finds itself facing a challenging question: How can drug manufacturers best harness all that data to improve capacity, reduce bottlenecks and cut costs? Establishing a strong digital backbone is the first critical step. From there, manufacturers need to figure out how to strengthen this digital backbone with technology that not only makes the data easily accessible, but also empowers manufacturers to analyze it and use it to make transformative predictions.
Mar 28, 2022
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Antibody That Opens Blood-Brain Barrier Might Also Ferry Lifesaving Drugs
Bio-IT World | A future where single-chain nanobodies and biologically active proteins might voyage through the blood-brain barrier to treat neurological conditions—including Alzheimer’s disease and brain tumors—recently came closer into view with the discovery of an antibody that succeeded in temporarily opening and resealing the crucial filtering mechanism in mice.
Mar 25, 2022
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Blueprint For Radically Open, Citizen Science Approach To Aging Research
Bio-IT World | Leonid Peshkin, Ph.D., is an unconventional man working at an Ivy League research university in a field he believes is rightfully viewed with “great skepticism” by mainstream biologists. The war on aging he is advancing puts to the test both interventions designed to extend healthspan (the period of life where one is healthy) and our understanding how the ravages of time get undone in the germline, an approach he likens to a Russian “Koschei” fairy tale where the secret to eternal health is in the egg.
Mar 23, 2022