• Unchanging Rules Of Gene Expression Could Improve Drug Approval Odds

    Bio-IT World | Network theory holds that everything is connected—including if the “nodes” are human cells, genomes, proteomes, or transcriptomes. It is “pure, algorithm-run precision math,” and it could be an entirely new approach to big data science that could erase the declining odds that a drug entering clinical studies will exit a winner.

    Aug 13, 2021
  • Spanish Team Builds Neural Network to Predict Small Molecule Characteristics

    Bio-IT World | A team of researchers in Barcelona have gathered bioactivity information for a million molecules using deep machine-learning computational models and a database of experimental results. Both the experimental results and the machine learning tool are available to the community at bioactivitysignatures.org.

    Aug 11, 2021
  • AI in Healthcare: Lessons Learned From Moffitt Cancer Center, Mayo Clinic

    Bio-IT World | Until recently, Ross Mitchell served as the inaugural AI Officer at the Moffitt Cancer Center in Tampa, Florida. Now he’s offering consulting expertise borne of a long career applying AI to healthcare and health systems.

    Aug 10, 2021
  • Follow the Money: RNA Therapeutics, AI-Driven Therapy Design

    Bio-IT World | Deep Genomics nets cash for AI-designed RNA therapeutics, Strata advances personalized minimal residual disease (MRD) assays, Frontier Medicines goes after the proteome, and more.

    Aug 5, 2021
  • #BioIT21: Insider’s Guide to Making the Most of the Hybrid Program

    Bio-IT World | The Bio-IT World Conference and Expo will be happening both in-person and online this year—giving our community even more options for learning and connection. We’ve been busy marking our schedules and making our plans. Here are our best tips for making the most both the in person and online options.

    Aug 4, 2021
  • NVIDIA’s Synthetic Brain Images, Genomic Research Diversity, New Products

    Bio-IT World | Kings College London uses NVIDIA’s Cambridge-1 supercomputer to build synthetic brain images, Singapore researcher detect SARS-CoV-2 in wastewater, American Heart Association Issues statement on genomic research diversity, and biobank acquisitions. Plus new products from 10x Genomics, Paradigm4, Thermo Fisher, Cresset.

    Aug 3, 2021
  • Russia Will Introduce Special Digital Genetic Passports

    Bio-IT World | Russia plans to introduce special digital genetic passports that will contain genome sequencing of each citizen of the country—the data could be further used for the formation of genetic profiles and identification of susceptibility to diseases, according to recent statements made by some senior officials of the Russian federal government and analysts.

    Jul 29, 2021
  • Duke, Regeneron, Micronoma Named 2021 Bio-IT World Innovative Practices Winners

    Bio-IT World | Bio-IT World has announced the 2021 Innovative Practices Awards winners. Grand prize awards were granted to Duke Cancer Institute with University of California, San Francisco, Micronoma, and Regeneron Pharmaceuticals. Pure Storage and the Folding@home project received honorable mention recognition. All four groups will be presenting their projects at the 2021 Bio-IT World Conference & Expo in Boston in September.

    Jul 28, 2021
  • NHGRI Takes New, WGS Look at Mendelian Diseases

    Bio-IT World | The National Institutes of Health has made a five-year, nearly $80 million commitment to the establishment of a Mendelian Genomics Research Consortium of five clinical laboratories and one data coordinating center. The Consortium will build on previous National Human Genome Research Institute (NHGRI) work to develop new methods for identifying the genetic causes of single-gene diseases.

    Jul 27, 2021
  • Sema4 Begins Trading, Eyes Healthcare Partnerships, Liquid Biopsy

    Bio-IT World | The board members of both Sema4 and CM Life Sciences voted this week to approve the special purpose acquisition company. The resulting combined company, Sema4 Holdings Corp, will commence trading of its shares of common stock and warrants on the Nasdaq Global Select Market under the ticker symbols "SMFR" and “SMFRW” today or Monday.

    Jul 23, 2021
  • DeepMind Releases Open Protein Structure Database Including Complete Human Proteome

    Bio-IT World | DeepMind and the European Molecular Biology Laboratory (EMBL) today unveiled the most complete and accurate database of predicted protein structure models for the human proteome. The database includes about 350,000 protein structures and will be freely and openly available to the scientific community.

    Jul 22, 2021
  • PacBio Acquires Short-Read Sequencer Omniome for $800M

    Bio-IT World | Pacific Biosciences announced this morning that it has signed a definitive merger agreement under which it will acquire Omniome, a San Diego-based company developing a highly differentiated, proprietary short-read sequencing platform capable of delivering high accuracy.

    Jul 20, 2021
  • Pfizer’s Digital Strategy and Transformation

    Bio-IT World | Bill Leister, Pfizer’s Senior Vice President of Advanced Analytics and Data Platforms & Learning and Development, discusses the pandemic, platforms, and Pfizer’s digital vision.

    Jul 20, 2021
  • Why NLP Is the Key to Interpreting Unstructured Data in Pharma Drug Discovery

    Bio-IT World | Natural language processing can help the pharma industry assess the market potential of a new drug, as well as target patient populations more accurately for existing drugs. NLP is much faster than human processing and can standardize mass amounts of both qualitative and quantitative unstructured data quickly into usable information with actionable insights.

    Jul 19, 2021
  • Inflammatory Clock Measures ‘Universal’ Hallmark Of Aging

    Bio-IT World | Systemic chronic inflammation—a universally strong signal of ill health associated with all nine hallmarks of aging and diseases that collectively represent the leading causes of disability and mortality worldwide—can now be measured by an inflammatory clock of aging (iAge) developed by investigators at the Stanford University School of Medicine and the Buck Institute for Research on Aging. It is the first “actionable clock” that predicts multimorbidity, frailty, immunological health, and chronic diseases of aging.

    Jul 15, 2021
  • Strateos Makes Cloud Lab Software Available to In-House Labs

    Bio-IT World | Strateos has launched its SmartLab Software which enables research organizations of any size to manage scientific workflows in-house while integrating automation with a modular, cloud-based software platform.

    Jul 13, 2021
  • Strep A Vaccine Development No Longer ‘A Bridge Too Far’

    Bio-IT World | In at least two, placebo-controlled randomized trials getting underway in the next year, participants will be purposefully infected with a strain of group A streptococcus (Strep A) causing acute pharyngitis (strep throat) in a human challenge test of candidate vaccines intended to confer protection.

    Jul 8, 2021
  • Clonally-Derived Workflows: The Need For Wrap Around Data Packages For Regulatory Submissions

    Bio-IT World | As part of regulatory submissions commercial labs are required to demonstrate that their clonal-derivation process is sound and that the high-value master cell submitted, did indeed, start from a single cell. Process validation (is the process fit for purpose?) and subsequent verification (is the process still fit for purpose?) becomes the backbone of clonal assurance.

    Jul 7, 2021
  • Implantable Pharmacy-On-a-Chip Now Under Fasttrack Development

    Bio-IT World | A trio of universities are putting their heads together to engineer a wirelessly controlled bioelectronic implant intended to help soldiers adapt to new time zones or drastic changes in their work schedules by releasing peptide-based therapies to harmonize their central and peripheral circadian clocks.

    Jul 6, 2021
  • Follow the Money: AI-Powered Drug Discovery, Remote Access Labs

    Bio-IT World | Insilico Medicine closes a Series C for AI-powered drug discovery, while other investments fuel remote access labs, natural products, high throughput screening, and more.

    Jul 1, 2021